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APC1Quiz5 Musculoske

Musculoskeletal

BrandGenericCategoryIndicationsSide EffectsUS Boxed WarningsOther Notes
Zanaflex tizanidine (PO) Alpha2 agonist Spasticity drowsiness, hypotension, dizziness, xerostomia, weakness
Plaquenil hydroxychloroquine (PO) Aminoquinolone RA, SLE, malaria retinal toxicity, rash, diarrhea long-term use has been associated with cardiomyopathy, bone marrow suppression, QT prolongation, and neuromuscular effects (i.e. myopathy, palsies, and progressive weakness)
Voltaren Gel (OTC) diclofenac (topical) NSAID OA pruritus, rash
Voltaren diclofenac (PO) NSAID OA, RA, acute pain diarrhea, dyspepsia, abdominal pain, flatulence, nausea may increase the risk of serious (and potentially fatal) cardiovascular thrombotic events, MI, and stroke; may increase the risk for serious (and potentially fatal) gastrointestinal adverse events including ulceration, bleeding, and perforation may reduce renal blood flow and compromise existing renal function (avoid in patients with renal disease, heart failure, and cirrhosis)
Motrin, Advil (all OTC) ibuprofen (PO) NSAID OA, RA, acute pain diarrhea, dyspepsia, abdominal pain, flatulence, nausea may increase the risk of serious (and potentially fatal) cardiovascular thrombotic events, MI, and stroke; may increase the risk for serious (and potentially fatal) gastrointestinal adverse events including ulceration, bleeding, and perforation may reduce renal blood flow and compromise existing renal function (avoid in patients with renal disease, heart failure, and cirrhosis)
Mobic meloxicam (PO) NSAID OA, RA, acute pain diarrhea, dyspepsia, abdominal pain, flatulence, nausea may increase the risk of serious (and potentially fatal) cardiovascular thrombotic events, MI, and stroke; may increase the risk for serious (and potentially fatal) gastrointestinal adverse events including ulceration, bleeding, and perforation may reduce renal blood flow and compromise existing renal function (avoid in patients with renal disease, heart failure, and cirrhosis)
Indocin indomethacin (PO) NSAID OA, RA, acute pain, gout diarrhea, dyspepsia, abdominal pain, flatulence, nausea may increase the risk of serious (and potentially fatal) cardiovascular thrombotic events, MI, and stroke; may increase the risk for serious (and potentially fatal) gastrointestinal adverse events including ulceration, bleeding, and perforation may reduce renal blood flow and compromise existing renal function (avoid in patients with renal disease, heart failure, and cirrhosis)
Naprosyn, Anaprox, Aleve (all OTC) naproxen (PO) NSAID OA, RA, acute pain, gout diarrhea, dyspepsia, abdominal pain, flatulence, nausea may increase the risk of serious (and potentially fatal) cardiovascular thrombotic events, MI, and stroke; may increase the risk for serious (and potentially fatal) gastrointestinal adverse events including ulceration, bleeding, and perforation may reduce renal blood flow and compromise existing renal function (avoid in patients with renal disease, heart failure, and cirrhosis)
Toradol keterolac (PO, IV) NSAID Pain diarrhea, dyspepsia, abdominal pain, flatulence, nausea may increase the risk of serious/fatal cardiovascular thrombotic events, MI, and stroke; may increase the risk for serious/fatal gastrointestinal adverse events including ulceration, bleeding, and perforation indicated for short term use (≤ 5 days) may reduce renal blood flow and compromise existing renal function (avoid in patients with renal disease, heart failure, and cirrhosis)
Celebrex celecoxib (PO) NSAID, COX-2 selective OA, RA, acute pain diarrhea, dyspepsia, abdominal pain, flatulence, nausea may increase the risk of serious (and potentially fatal) cardiovascular thrombotic events, MI, and stroke; may increase the risk for serious (and potentially fatal) gastrointestinal adverse events including ulceration, bleeding, and perforation may reduce renal blood flow and compromise existing renal function (avoid in patients with renal disease, heart failure, and cirrhosis)
Flexeril, Amrix, Fexmid cyclobenzaprine (PO) Skeletal muscle relaxant Muscle spasm drowsiness, dizziness, xerostomia, fatigue use may cause prolonged cardiac arrhythmias, and tachycardia; CI within 14 days of MAOI therapy
--- baclofen (PO) Skeletal muscle relaxant Spasticity drowsiness
Robaxin methocarbamol (PO) Skeletal muscle relaxant Muscle spasm drowsiness
Transdermal: Lidoderm (OTC) IV: Xylocaine lidocaine (transdermal, IV) Transdermal: topical analgesic IV: antiarrhythmic Transdermal: pain IV: ventricular arrhythmias Transdermal: dermatitis, erythema, urticaria, skin depigmentation, skin edema IV: bradycardia patch may remain in place for up to 12 hours in any 24-hour period, patch may be cut
Colcrys colchicine (PO) Antigout agent Gout diarrhea, nausea, vomiting, bone marrow suppression, myopathy (including rhabdomyolysis)
Zyloprim allopurinol (PO) Xanthine oxidase inhibitor Gout diarrhea, nausea, rash, leukopenia, thrombocytopenia rare association with severe (and potentially fatal) allopurinol hypersensitivity syndrome (risk highest in certain Asian populations)
Anectine succinylcholine (IV) Depolarizing neuromuscular blocking agent Neuromuscular blockade for intubation for procedures hyperkalemia, myalgia, malignant hyperthermia (rare) acute rhabdomyolysis and hyperkalemia leading to cardiac arrest and death in pediatric patients with undiagnosed skeletal muscle disease
Enbrel etanercept (SQ) Anti-tumor necrosis factor alpha inhibitor RA infection, injection site reaction, headache, nausea serious infections, malignancies such as lymphoma
Humira adalimumab (SQ) Anti-tumor necrosis factor alpha inhibitor RA, Crohn's Disease, Ulcerative Colitis infection, injection site reaction, headache, nausea serious infections, malignancies such as lymphoma
Created by: salmouie
 

 



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