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Top Drugs
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| Term | Definition |
|---|---|
| lisinopril (brand) | zestril |
| lisinopril (class) | angiotensin converting enzyme (ACE) inhibitor |
| lisinopril (category) | antihypertensive |
| lisinopril (BMA) | inhibits the conversion of angiotensin I to angiotensin II, causing vasodilation and reduction in the release of aldosterone |
| amlodipine (brand) | norvasc (tab), norliqva (soln), katerzia (susp) |
| amlodipine (class) | calcium channel blocker |
| amlodipine (category) | antihypertensive |
| amlodipine (BMA) | inhibits the influx of calcium ions into vascular smooth muscle and cardiac muscle, resulting in decreased peripheral vascular resistance and reduced blood pressure |
| losartan (brand) | cozaar |
| losartan (class) | angiotensin II receptor blocker (ARB) |
| losartan (category) | antihypertensive |
| losartan (BMA) | selectively blocks the binding of angiotensin II to the AT1 receptor, preventing vasoconstriction and reducing the secretion of aldosterone |
| hydrochlorothiazide (brand) | microzide, hydrodiuril, aquazide h |
| hydrochlorothiazide (class) | thiazide diuretic |
| hydrochlorothiazide (catergory) | antihypertensive |
| hydrochlorothiazide (BMA) | inhibits sodium reabsorption in the distal tubules causing increased excretion of sodium and water, as well as potassium and hydrogen ions |
| furosemide (brand) | lasix |
| furosemide (class) | loop diuretic |
| furosemide (catergory) | antihypertensive |
| furosemide (BMA) | inhibits the reabsorption of sodium and chloride in the ascending loop of Henle and distal renal tubule |
| atenolol (brand) | tenormin |
| atenolol (class) | beta blocker |
| atenolol (category) | antihypertensive |
| atenolol (BMA) | selectively blocks beta 1 adrenergic receptors in the heart decreasing heart rate and contractility |
| bisoprolol (brand) | cardicor |
| bisoprolol (class) | beta blocker |
| bisoprolol (category) | antihypertensive |
| bisoprolol (BMA) | selectively blocks beta 1 adrenergic receptors in the heart decreasing heart rate and contractility |
| carvedilol (brand) | coreg |
| carvedilol (class) | beta blocker with alpha blocking activity |
| carvedilol (category) | antihypertensive |
| carvedilol (BMA) | nonselectively blocks beta adrenergic receptors and alpha 1 adrenergic receptors, leading to decreased heart rate, contractility, and increased vasodilation |
| propranolol (brand) | inderal |
| propranolol (class) | beta blocker |
| propranolol (cateogory) | antihypertensive |
| propranolol (BMA) | nonselectively blocks beta adrenergic receptors, reducing heart rate and contractility |
| nifedipine (brand) | procardia |
| nifedipine (class) | calcium channel blocker |
| nifedipine (category) | antihypertensive |
| nifedipine (BMA) | inhibits the influx of calcium ions into vascular smooth muscle and cardiac muscle, resulting in decreased peripheral vascular resistance and reduced blood pressure |
| hydralazine (brand) | apresoline |
| hydralazine (class) | vasodilator |
| hydralazine (category) | antihypertensive |
| hydralazine (BMA) | directly relaxes arteriolar smooth muscle, reducing peripheral vascular resistance |
| valsartan (brand) | diovan |
| valsartan (class) | angiotensin II receptor blocker (ARB) |
| valsartan (category) | antihypertensive |
| valsartan (BMA) | selectively blocks the binding of angiotensin II to the AT1 receptor, preventing vasoconstriction and reducing the secretion of aldosterone |
| olmesartan (brand) | benicar |
| olmesartan (class) | angiotensin II receptor blocker (ARB) |
| olmesartan (category) | antihypertensive |
| olmesartan (BMA) | selectively blocks the binding of angiotensin II to the AT1 receptor, preventing vascoconstriction and reducing the secretion of aldosterone |
| enalapril (brand) | vasotec |
| enalapril (class) | angiotensin converting enzyme (ACE) inhibitor |
| enalapril (category) | antihypertensive |
| enalapril (BMA) | inhibits the conversion of angiotensin I to angiotensin II, causing vasodilation and reduction in the release of aldosterone |
| clonidine (brand) | catapres |
| clonidine (class) | alpha 2 adrenergic agonist |
| clonidine (category) | antihypertensive |
| clonidine (BMA) | stimulates alpha 2 adrenergic receptors in the brainstem, reducing sympathetic outflow and decreasing blood pressure |
| diltiazem (brand) | cardizem |
| diltiazem (class) | calcium channel blocker |
| diltiazem (category) | antihypertensive |
| diltiazem (BMA) | inhibits the influx of calcium ions into vascular smooth muscle, leading to vasodilation and reduced heart rate |
| verapamil (brand) | calan, verelan |
| verapamil (class) | calcium channel blocker |
| verapamil (category) | antihypertensive |
| verapamil (BMA) | inhibits the influx of calcium ions into vascular smooth muscle, leading to vasodilation and reduced heart rate |
| metoprolol (brand) | lopressor (tartrate), toprol XL (succinate) |
| metoprolol (class) | beta blocker |
| metoprolol (category) | antihypertensive |
| metoprolol (BMA) | selectively blocks beta 1 adrenergic receptors in the heart and smooth muscle, decreasing heart rate and contractility |
| spironolactone (brand) | aldactone |
| spironolactone (class) | potassium sparing diuretic; aldosterone receptor antagonist |
| spironolactone (category) | antihypertensive |
| spironolactone (BMA) | competes with aldosterone in the distal renal tubules, increasing sodium and water excretion while conserving potassium and hydrogen ions; may block the effect of aldosterone on arteriolar smooth muscle as well |
| chlorthalidone (brand) | hemiclor, thalitone |
| chlorthalidone (class) | thiazide diuretic |
| chlorthalidone (category) | antihypertensive |
| chlorthalidone (BMA) | inhibits sodium reabsorption in the distal tubules causing increased excretion of sodium and water, as well as potassium and hydrogen ions |
| simvastatin (brand) | zocor |
| simvastatin (class) | HMG- CoA Reductase Inhibitor (statin) |
| simvastatin (category) | antilipemic |
| simvastatin (BMA) | inhibits HMG-CoA reductase, reducing cholesterol synthesis and increasing LDL update from the blood |
| rosuvastatin (brand) | crestor |
| rosuvastatin (class) | HMG-CoA Reductase Inhibitor (Statin) |
| rosuvastatin (category) | antilipemic |
| rosuvastatin (BMA) | inhibits HMG-CoA reductase, reducing cholesterol synthesis and increasing LDL update from the blood |
| atorvastatin (brand) | lipitor |
| atorvastatin (class) | HMG-CoA Reductase Inhibitor (Statin) |
| atorvastatin (category) | antilipemic |
| atorvastatin (BMA) | inhibits HMG-CoA reductase, reducing cholesterol synthesis and increasing LDL update from the blood |
| pravastatin (brand) | pravachol |
| pravastatin (class) | MHG-CoA Reductase inhibitor (statin) |
| pravastatin (BMA) | inhibits HMG-CoA reductase, reducing cholesterol synthesis and increasing LDL update from the blood |
| fenofibrate (brand) | tricor |
| fenofibrate (class) | fibric acid derivative |
| fenofibrate (category) | antilipemic |
| pravastatin (category) | antilipemic |
| fenofibrate (BMA) | activates peroxisome proliferator-activated receptor alpha (PRAR-alpha), leading to increased lipolysis and elimination of triglyceride-rich particles |
| niacin (brand) | niaspan (DSD), niacor |
| niacin (class) | nicotinic acid |
| niacin (category) | antilipemic |
| niacin (BMA) | inhibits lipolysis in adipose tissue, reduces hepatic VLDL synthesis, and increased HDL levels |
| omega-3-acid ethyl esters (brand) | lovaza |
| omega-3-acid ethyl esters (class) | omega-3 fatty acid |
| omega-3-acid ethyl esters (category) | antilipemic |
| omega-3-acid ethyl esters (BMA) | reduces hepatic triglyceride synthesis and increases plasma lipoprotein lipase activity |
| ezetimibe (brand) | zetia |
| ezetimibe (class) | cholesterol absorption inhibitor |
| ezetimibe (category) | antilipemic |
| ezetimibe (BMA) | inhibits the absorption of cholesterol at the brush border of the small intestine |
| evolocumab (brand) | repatha |
| evolocumab (class) | PCSK9 inhibitor |
| evolocumab (category) | antililpemic |
| evolocumab (BMA) | inhibits proprotein convertase subtilisin/kexin type 9 (PCSK 9) which degrades LDL receptors; increases the number of LDL receptors available to clear LDL |
| alirocumab (brand) | praluent |
| alirocumab (class) | PCSK 9 inhibitor |
| alirocumab (category) | antilipemic |
| alirocumab (BMA) | inhibits proprotein convertase subtilisin/kexin type 9 (PCSK 9) which degrades LDL receptors; increases the number of LDL |
| inclisiran (brand) | leqvio |
| inclisiran (class) | small interfering ribonucleic acid (siRNA) agent |
| inclisiran (category) | antililpemic |
| inclisiran (BMA) | inhibits the synthesis of proprotein convertase subtilisin/E47kexin type 9 (PCSK9), increasing the number of LDL receptors available to clear LDL |
| warfarin (brand) | coumadin |
| warfarin (class) | vitamin k antagonist |
| warfarin (category) | anticoagulant |
| warfarin (BMA) | inhibits the synthesis of vitamin k dependent clotting factors II, VII, IX, and X |
| rivaroxaban (brand) | Xarelto |
| rivaroxaban (class) | direct factor Xa inhibitor |
| rivaroxaban (category) | anticoagulant |
| rivaroxaban (BMA) | inhibits factor Xa, preventing the conversion of prothrombin to thrombin |
| apixaban (brand) | eliquis |
| apixaban (class) | direct factor Xa inhibitor |
| apixaban (BMA) | inhibits factor Xa, preventing the conversion of prothrombin to thrombin |
| apixaban (category) | anticoagulant |
| heparin (brand) | hep-lock |
| heparin (class) | anticoagulant |
| heparin (category) | anticoagulant |
| heparin (BMA) | enhances the activity of antithrombin III, inhibiting thrombin and factor Xa |
| enoxaparin (brand) | lovenox |
| enoxaparin (class) | low molecular weight heparin |
| enoxaparin (category) | anticoagulant |
| enoxaparin (BMA) | enhances the activity of antithrombin III, inhibiting thrombin and factor Xa |
| amiodarone (brand) | Nexterone (soln), Pacerone (tab) |
| amiodarone (class) | Class III Antiarrhythmic |
| amiodarone (category) | antiarrhythmic |
| amiodarone (BMA) | inhibits potassium channels responsible for repolarization of the cardiac cell membrane; prolongs the action potential and refractory period of cardiac celia |
| sotalol (brand) | betapace |
| sotalol (class) | class III antiarrhythmic |
| sotalol (category) | antiarrhythmic |
| sotalol (BMA) | nonselectively blocks beta adrenergic receptors and potassium channels to prolong the action potential and refractory period of cardiac cells |
| lidocaine (brand) | xylocaine |
| lidocaine (class) | local anesthetic; class 1b antiarrhythmic |
| lidocaine (category) | antiarrhythmic |
| lidocaine (BMA) | inhibits sodium channels, inhibiting nerve impulse conduction |
| digoxin (brand) | lanoxin |
| digoxin (class) | cardiac glycoside |
| digoxin (category) | antiarrhythmic |
| digoxin (BMA) | affects parasympathetic stimulation, slowing conduction through the AV node and slowing heart rate |
| dofetilide (brand) | tikosyn |
| dofetilide (class) | class III antiarrhythmic |
| dofetilide (category) | antiarrhythmic |
| dofetilide (BMA) | inhibits potassium channels responsible for repolarization of the cardiac cell membrane; prolongs the action potential and refractory period of cardiac cells |
| metformin (brand) | glucophage |
| metformin (class) | biguanide |
| metformin (category) | antidiabetic |
| metformin (BMA) | decreases hepatic glucose production, decreases intestinal absorption of glucose, and improves insulin sensitivity by increasing peripheral glucose uptake |
| insulin glargine (brand) | Lantus, Basaglar, Toujeo, and Semglee |
| insulin glargine (class) | long acting insulin |
| insulin glargine (caterogry) | antidiabetic |
| insulin glargine (BMA) | functions as basal glycemic control by regulating glucose metabolism; stimulates glucose uptake in skeletal muscle and fat and inhibits hepatic glucose productions |
| insulin lispro (brand) | Humalog, Admelog, and Lyumjev |
| insulin lispro (class) | rapid acting insulin |
| insulin lispro (category) | antidiabetic |
| insulin lispro (BMA) | functions as bolus glycemic control by regulating glucose metabolism; stimulates glucose uptake in skeletal muscle and fat and inhibts hepatic glucose production |
| insulin aspart (brand) | Novolog, Fiasp, and Merilog |
| insulin aspart (class) | rapid acting insulin |
| insulin aspart (category) | antidiabetic |
| insulin aspart (BMA) | functions as bolus glycemic control by regulating glucose metabolism; stimulates glucose uptake in skeletal muscle and fat and inhibits hepatic glucose production |
| liraglutide (brand) | Victoza, and Saxenda |
| liraglutide (class) | GLP-1 Receptor Agonist |
| liraglutide (category) | antidiabetic |
| liraglutide (BMA) | activates glucagon like peptide 1 (GLP-1) receptor to enhance glucose-dependent insulin secretion, decrease inappropriate glucagon secretion, slow gastric emptying, and decrease food intake |
| semaglutide (brand) | Ozempic, and Wegovy |
| semaglutide (class) | GLP-a Receptor Agonist |
| semaglutide (category) | antidiabetic |
| semaglutide (BMA) | activated GLP-1 receptor to enhance glucose dependent inulin secretion, decrease inappropriate glucagon secretion, slow gastric emptying, and decrease good intake |
| dulaglutide (brand) | Trulicity |
| dulaglutide (class) | GLP-1 Receptor Agonist |
| dulaglutide (catergory) | antidiabetic |
| dulaglutide (BMA) | activate GLP-1 receptor to enhance glucose dependent insulin secretion, decrease inappropriate glucagon secretion, slow gastric emptying, and decrease food intake |