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Respiratory
Respirstory
| Question | Answer |
|---|---|
| Antihistamines | • Cause pupil dilation (mydriasis) and bronchoconstriction. • Decrease renal drug clearance, especially in cardiac and kidney disease. • Contraindicated in hypertension, BPH, COPD, and asthma due to bronchoconstriction risk. • Adverse reactions: s |
| Decongestants | • Reduce nasal swelling for sinus drainage (relieve congestion). • Used for common cold, allergic rhinitis, and sinusitis. • Example: Sudafedrine (Afrin). • Contraindicated in glaucoma, heart disease, hypertension, diabetes, hypothyroidism, stroke |
| Antitussives | • Depress cough center in the brain to relieve cough. • Opioids: Codeine, hydrocodone; Non-opioids: Tessalon Pearls. • Used to relieve cough, particularly for cancer patients with dry cough. • Adverse reactions: sedation, constipation, liver/renal |
| Mucolytics | • Reduce the thickness (viscosity) of secretions, making mucus easier to expel. • Used for cystic fibrosis (thick mucus), acetaminophen overdose. • Example: Mucomyst. • Adverse reactions: drowsiness, bronchospasm, stomatitis, hypotension. • Nurs |
| Expectorants | • Increase and thin secretions to help cough up mucus. • Used for productive cough, chronic lung diseases (COPD, emphysema, asthma, chronic bronchitis, pulmonary fibrosis). • Example: Guaifenesin (Mucinex). • Adverse reactions: dizziness, headache |
| Bronchodilators | • Relax smooth muscle to dilate bronchi, promoting easier breathing. • Used for bronchospasm, asthma, bronchitis, emphysema. • Example: Albuterol (short-acting). • Contraindicated in uncontrolled hypertension, arrhythmias. • Adverse reactions: tac |
| Xanthine Derivatives | • Stimulate CNS and promote bronchodilation; prevent/relieve asthma and bronchospasm. • Example: Theophylline (therapeutic level 10–20). • Contraindicated in allergies, uncontrolled dysrhythmias. • Adverse reactions: tachycardia, palpitations, EKG |
| Inhaled Corticosteroids | • Reduce airway inflammation and hyper-responsiveness (long-term asthma control). • Examples: Flovent, Pulmicort, Atrovent. • Contraindicated in drug/glucocorticoid allergy, fungal infection. • Adverse reactions: adrenal suppression, yeast infecti |
| Leukotriene Modifiers | • Decrease leukotriene production to reduce airway inflammation. • Used for chronic asthma (age 12+), not for acute attacks. • Example: Singulair. • Contraindicated in drug allergy; interactions decrease effectiveness. • Adverse reaction: dyspepsi |
| Mydriasis | pupil dilation |
| BPH | benign prostatic hyperplasia |
| COPD | chronic obstructive pulmonary disease |
| Bronchoconstriction | narrowing of airways |
| Bronchodilation | widening of airways |
| Xanthine derivatives | CNS stimulants for bronchodilation (e.g., theophylline |
| Adrenal suppression | reduced adrenal function due to steroids |
| Leukotriene modifiers | drugs that reduce airway inflammation by blocking leukotriene |