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ID Quiz 2

GenericBrandDrug ClassIndicationMOAAEC/IBBWROA
Ampicillin + Sulbactam Unasyn Pencillin, antibiotic Bacterial Infections Inhibits bacterial cell wall synthesis Allergy to any beta-lactam abx, mononucleosis, hypersensitivity rxn, caution in liver impairment due to reported hepatotoxicity IM, IV
Cefazolin Ancef Cephalosporin , 1st gen Biliary tract, bloodstream, bone and genital, respiratory tract, skin and soft tissue, and urinary tract infections. Endocarditis tx. Surgical prophylaxis Inhibits bacterial cell wall synthesis Caution in patients with hx of seizure, high levels - particularly in renal impairment - may increase risk, or hypersensitivity to beta-lactams or PCNs IM, IV
Cefepime Maxipime Cephalosporin, 4th gen Intra-abdominal infection, neutropenic fever, mod-severe pneumonia, skin and soft tissue infection, complicated UTI Inhibits bacterial cell wall synthesis Severe neurologic rxns, including seizures and nonconvulsive status. Risk may be increased with renal impairment. Hypersensitivity to PCNs or beta-lactams IM, IV
Cefoxitin Mefoxin Cephalosporin, 2nd gen Sepsis, surgical prophylaxis, and bloodstream, bone and joint, gynecological, intraabdominal, lower respiratory tract, skin and soft tissue, and urinary tract infections. Inhibits bacterial cell wall synthesis Pts <3 mo, higher doses associated with eosinophilia and elevated AST IM, IV
Ceftriaxone Rocephin Cephalosporin, 3rd gen Bloodstream, bone and joint, uncomplicated gonococcal, mild-mod intra-abdominal, lower respiratory tract, skin and soft tissue, and complicated urinary tract infections. Bacterial meningitis, acute otitis media, colorectal surgical prophylaxis Inhibits bacterial cell wall synthesis Hyperbilirubinemic neonates, concurrent use with IV calcium containing solutions in neonates IM, IV
Cefuroxime Zinacef, Ceftin Cephalosporin, 2nd gen Bone and joint, lower respiratory tract, skin and structure infections (impetigo), and urinary tract infections. Acute COPD exacerbation, early Lyme disease, acute otitis media, septicemia, acute bacterial sinusitis, group A strep, & surgical prophylaxis Inhibits bacterial cell wall synthesis Tablets and oral suspension not 1:1. Hypersensitivity to beta-lactams IM, IV
Clarithromycin Biaxin Macrolide antibiotic Acute exacerbation of COPD, H. pylori eradication, mycobacterial (non-TB) infection, otitis media, CAP, acute bacterial rhinosinusitis, skin/skin structure infection, or group A streptococcal pharyngitis Binds to 50S ribosomal subunit, resulting in inhibition of protein synthesis Potentially significant interactiosn may exist with CYP3A4 metabolism, including some statins. Hx of QT prolongation or ventricular arrhythmias. Oral
Fidaxomicin Dificid Macrolide antibiotic C. diff Inhibits RNA polymerase sigma subunit resulting in inhibition of protein synthesis Do not use for systemic inefctions, absorption is negligible Oral
Gentamicin Garamycin Aminoglycoside antibiotic Serious, dermatologic or ophthlamic infections Inhibits protein synthesis D/c if nephrotoxicity May cause neurotoxicity such as neuromuscular blockade and respiratory paralysis, especially when given after anesthesia or NM blockers. Risk factors include pre-existing renal impairment, concomitant nephrotoxic med, advanced age, dehydration. IM, IV, ophthalmic, topical
Imipenem + Cilastatin Primaxin Carbapenem antibiotic Gram-negative bactermia blood stream, bone and joint, gynecologic, intra-abdominal, mod-severe skin and soft tissue, and urinary tract infections. Endocarditis and penumonia. Inhibits bacterial cell wall synthesis CNS adverse effects including confusional states and seizures (myclonic). May decrease serum conc of divalproex IV
Linezolid Zyvox Oxazolidinone Vancomycin resistant enterococcal infections, pneumonia, and skin and skin structure infections Binds to 23S ribosomal RNA of 50S subunit Avoid use in patients with other serotonergic drugs which may reduce linezolid's metabolism unless clinically appropriate and under close monitoring. IV, oral
Meropenem Merrem Carbapenem antibiotic Intra-abdominal infection, bacterial meningitis, mod-severe skin and skin structure infection Inhibits bacterial cell wall synthesis Use with caution in pts with renal impairment. Increased risk of seizure and thrombocytopenia have been reported in pts with renal impairment. Dosage adj required with CrCl <50 mL/min. IV
Moxifloxacin Fluoroquinolone antibiotic Mild-moderate CAP, bacterial conjunctivitis Inhibits DNA gyrase, topoisomerase IV avoid use in pts who experience serious adverse reactions of tendonitis, tendon rupture, etc. May increase risk of tendonitis, tendon rupture, peripheral neuropathy, and CNS effects. IV, ophthalmic
Penicillin V Potassium Pen VK Penicillin antibiotic Erysipelas, acute simple plaque-associated gingivitis, pneumococcal infections, group A streptococcus, group A pharyngitis streptococcus Inhibits bacterial cell wall synthesis Prolonged use may result in fungal or bacterial superinfection Oral
Piperacillin + Tazobactam Zosyn Penicillin antibiotic Intra-abdominal infections, pelvic infection, CAP, skin and soft tissue infection Inhibits bacterial cell wall synthesis Hypersensitivity to PCNs or beta-lactams. Risk of nephrotoxicity increased when given w/ vanco. IV
Tobramycin Tobradex Aminoglycoside antibiotic Bloodstream infections, bone infections, intra-abdominal infections, bacterial meningitis, pneumonia, skin and skin structure infections, complicated UTI Inhibits protein synthesis D/c if signs of nephrotoxicity, ototoxicity May cause nephrotoxicity, neuromuscular blockade, respiratory paralysis, ototoxicity (tinnitus or vertigo) IM, IV, ophthalmic, oral inhalation
Vancomycin Vancocin, Firvanq Glycopeptide antibiotic C. diff, endocarditis, enterocolitis, staphylococcal infection Blocks glycopeptide polymerization through binding tightly to D-alanyl-D-alanine portion of cell wall precursor Solutions containing dextrose may be C/I in patients with allergy to corn or corn products. The formulation containing the excipients PEG 400 and NADA is not recommended for use during pregnancy due to fetal malformations in animal studies. IV
Created by: hmariner1
 

 



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