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ID Quiz 1
| Generic | Brand | Drug Class | Indication | MOA | AE | C/I | BBW | ROA |
|---|---|---|---|---|---|---|---|---|
| Amoxicillin | Amoxil, Moxatag | Penicillin antibiotic, beta-lactam | Bacterial infections | Inhibits cell wall synthesis | N/V/D, rash | Allergy to any beta-lactam | N/A | Oral, enteral feeding |
| Amoxicillin + Clavulanate | Augmentin (ES, XR) | Penicillin antibiotic, beta-lactam | Bacterial infections | Inhibits cell wall synthesis | N/V/D, rash | Allergy to any beta-lactam | N/A | IV (canada), oral, enteral feeding |
| Azithromycin | Zithromax | Macrolide antibiotic | Bacterial infections | Inhibits protein synthesis | N/V/D, abdominal pain | Allergy to any macrolide antibiotic | N/A | IV, oral, enteral feeding tube, ophthalmic |
| Cefdinir | Omnicef | Cephalosporin, 3rd gen | Bacterial infections | Inhibits cell wall synthesis | N/D, HA, abdominal pain | Caution if allergic to PCN antibiotics | N/A | Oral |
| Cephalexin | Keflex | Cephalosporin, 1st gen | Bacterial infections | Inhibits cell wall synthesis | N/V/D, rash, headache, dizziness | Caution if allergic to PCN antibiotics | N/A | Oral, enteral feeding tube |
| Ciprofloxacin | Cipro (XR) | Fluoroquinolone antibiotic | Bacterial infections | Inhibits DNA gyrase | Dizziness, sweating, headache, nervousness, confusion, rash, tendonitis | Patients > 60 yo, heart arrhythmias, HTN, myasthenia gravis | May increase risk of tendonitis and tendon ruptures in the elderly | IV, oral, enteral feeding |
| Clindamycin | Cleocin | Lincosamide | Bacterial infections | Inhibits protein synthesis | N/V/D, rash, abdominal pain, itching, rash, metallic taste | Neonates, UC | Risk of severe diarrhea and C. Diff infection | IM, IV, oral, topical, intravaginal enteral feeding tube |
| Doxycycline | Doryx, Monodox, Periostat, Vibramycin | Tetracycline antibiotic | Bacterial infections | Inhibits protein synthesis | N/V/D, loss of appetite | Pregnancy, lactation, pts < 8 yo | Risk of severe diarrhea and C. Diff infection | IV, oral, intrapleural (off-label) |
| Hydroxychloroquine | Plaquenil | DMARDs | RA, malaria, Covid-19 (investigational) | Unknown | N/V, dizziness, ataxia, HA, abdominal pain, vomiting, vision changes | Retinal or vision problems | Prescribers must be familiar with complete prescribing guidelines before use | Oral |
| Levofloxacin | Levaquin | Fluoroquinolone antibiotic | Bacterial infections | Inhibits DNA gyrase | N/V/D, rash, HA, dizziness | Pts > 60 yo, QT prolongation, aortic aneurysm hx or risk, HTN, PVD | May increase risk of tendonitis and tendon ruptures in the elderly | IV, oral, ophthalmic, oral inhalation, enteral feeding |
| Metronidazole | Flagyl (ER) | Nitroimidazol, 1st gen | Bacterial infections, amebiasis | Inhibits nucleic acid synthesis | N/V/D, stomach discomfort, rash, HA, dizziness, metalic taste | 1st trimester pregnancy, alcohol use during or after 14 days of use | Carcinogenic in mice, avoid unnecessary use | IV, oral, topical, intravaginal |
| Minocycline | Minocin, Solodyn | Tetracycline antibiotic | Bacterial infections | Inhibits nucleic acid synthesis | N/V/D, stomach discomfort, rash, HA, dizziness, metalic taste | Pregnancy, lactation | N/A | IV, oral, topical |
| Mupirocin | Centany | Antibiotic, topical | Impetigo, secondary skin infections, MRSA decolonization | Reversibly binds to isoleucyl-tRNA synthetase, inhibiting protein synthesis | HA, stinging sensation, pruritis, rhinitis, cough, dysgeusia, pharyngitis, skin rash | N/A | N/A | Topical |
| Nitrofurantoin | Furadantin, Macrodantin, Macrobid | Imidazolidinedione | Bacterial skin infections | Inhibits DNA, RNA, protein and cell wall synthesis | N, burning, headache, rash, itching | Large open wounds | N/A | Oral |
| Sulfamethoxazole + Trimethoprim | Bactrim (DS), Sulfatrim | Sulfonamide antibiotic | Bacterial infection | PABA competitor - inhibits folic acid synthesis | N/V/D, headache, rash, itching, photosensitivity | Allergy to any sulfonamides, pt < 2 mo, anemia | N/A | IV, oral, enteral feeding tube |
| Phenazopyridine | Azo, Pyridium | Analgesic, urinary | Symptom relief of UTI | Unknown | Discoloration of urine, skin, and eyes | GFR < 50 mL/min, D/c if skin develops yellow color | N/A | Oral |
| Rifaximin | Xifaxan | Antibiotic, rifamycin | IBS-D, hepatic encephalopathy, traveler's diarrhea | Irreversibly binds to RNA polymerase, inhibiting RNA and protein synthesis | N/A | N/A | N/A | Oral |