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Nerve Impulse
| Question | Answer |
|---|---|
| Explain what is meant by reaching threshold at the synapse. | minimum number of receptors that have to bind to their receptor to generate an impulse. |
| In the presynaptic neuron the neurotransmitter is held in a | vesicle |
| What causes the vesicle to move to the membrane and fuse with it | An electrical impulse along the axon |
| After the neurotransmitter is released into the synapse it then | diffuses across synapse and binds to post synaptic receptors |
| State one way the neurotransmitter is removed from the synapse | enzyme or reuptake protein into pre synaptic neuron |
| Explain why it is important to remove the neurotransmitter from the synapse | To prevent repeated stimulation |
| Name two neurotransmitters | 1, endorphin 2, dopamine 3, noradrenaline 4. acetylcholine |
| The neurotransmitter that reduces pain intensity is | endorphin |
| The neurotransmitter associated with pleasure is | dopamine |
| Dopamine activates which part of the brain to reinforce pleasurable behaviour | reward pathway |
| State an activity that would cause endorphins to be produced | 1. sex 2. prolonged exercise 3. eating food |
| Name the chemical that mimicks the neurotransmitter at a synapse by binding to the receptor | agonist |
| Name the chemical that binds to and blocks the neurotransmitter binding | antagonist |
| Apart from an agonist drug, state another way the dopamine levels can be elevated in the synapse | 1. enzyme inhibitor 2. reuptake inhibitor |
| Addiction is caused by | antagonists |
| Agonist drugs long term cause | tolerance |
| Antagonist drugs block receptors resulting in | sensitisation of receptors |
| Agonist drugs taken repeatedly result in | desensitisation of receptors |
| Which process results in cravings; addiction OR tolerance | addiction |
| Name one way illegal drugs affect neurotransmission | 1.mood 2. behaviour 3.emotion 4. cognition |
| Which process results in you needing to take more drug to get the same effect | tolerance (desensitised receptors require more drug) |
| Illegal drugs activate the reward pathway releasing which neurotransmitter | dopamine |
| Converging pathways enable threshold to be reached when there is a weak stimulus by | summation of weak stimuli |