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Immune System
| Question | Answer |
|---|---|
| Name the 3 types of non specific defences | 1. physical barriers 2. chemical secretions 3. inflammatory response |
| Describe a physical barrier | Closely packed epithelial cells in respiratory/digestive system. |
| State two examples of chemical secretions | 1. tears 2. salvia 3. mucus 4. hydrochloric acid |
| State the name of the white blood cells that release histamine in the inflammatory response | mast cells |
| Explain why blood flow increases after histamine release | vasodilation of arterioles OR increased capillary permeability |
| Explain the importance of increased blood flow to an area of inflammation/infection | phagocytes AND clotting factors brought to area |
| Describe the process of phagocytosis | Phagocyte engulfs pathogen and digestive enzymes destroy pathogen |
| Explain how phagocytes accumulate at the site of infection | phagocytes release cytokines to cause more phagocytes to accumulate |
| State the type of white blood cell in the specific immune system | Lymphocytes |
| Which type of lymphocyte does apoptosis | T lymphocytes |
| Define apoptosis | Programmed cell death |
| Describe what happens after a specific T lymphocyte binds to a specific pathogen | protein diffuses into infected cell |
| Describe the impact of protein being released into the cell during apoptosis | Activates self destructive enzymes which calls self death |
| Describe what is meant by autoimmune disease | When T lymphocytes react to self antigens destroying the body's own cells. |
| Describe the impact of HIV on the immune system. | Destroys T lymphocytes |
| Explain why those with HIV are more susceptible to opportunistic infections | They have a weakened immune system |
| Name the cells that survive long term after clonal selection of B and T lymphocytes | B and T lymphocytes |
| Describe one way s secondary response to same antigens differ | 1. faster response 2. higher concentration of antibodies produed 2. antibodies stay higher for longer. |
| Repeated B or T lymphocyte cell division following binding to a specific antigen is called | Clonal selection |
| State the protein B lymphocytes produce that is specific to a particular antigen | antibody |
| When antibodies bind to specific antigens forming an antibody antigen complex this | renders antigens harmless |
| Describe what happens after an antibody antigen complex is formed | Phagocytes accumulate due to cytokines causing phagocytosis |
| State what type of lymphocytes causes allergy | B lymphocytes |
| Explain how B lymphocytes cause allergy | Hypersensitive and react to antigens on harmless substances. |