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The genetic code
| Term | Definition |
|---|---|
| The Genetic code has 3 features | Degenerate Universal Non overlapping |
| What is a start codon | At the start of every gene there is a start codon TAC in DNA or AUG in mRNA. This codes for the amino acid methionine. This methionine is later removed from the protein if it is not actually needed for the structure. |
| What stop codons | At the end of every gene there are 3 bases that do no code for an amino acid and is known as a "stop codon". These stop codons mark the end of a polypeptide chain and cause ribosomes to detach and therefore stop translation. |
| What are the stop codons | ATT, ATC, ACTT, DNA |
| The feature degenerate has | 20 amino acids that the genetic code has to be able to code for. There are four DNA bases and therefore three bases are needed to make enough combinations to code for at least 20 amino acids. This can be proven mathematically. |
| Examples 1 bases coded for a amino acids | If one base coded for one amino acid this would only allow for 4 amino acids to be coded for. This is insufficient to code for 20 amino acids |
| Example 2 bases coded for a amino acids | If 2 bases coded for one amino acid this would allow for 16 amino acids to be coded for. This is insufficient to code for 20 amino acids |
| Example 3 bases coded for amino acids | If 3 bases coded for one amino acid this would allow for 64 amino acids to be coded for |
| What does degenerate mean | In the genetic code this is when multiple codons can code for the same amino acid. |
| Why is a degenerate a advantage | This is an advantage as if a point mutation occurs even though the triplet of bases will be different it may still code for the same amino acid and therefore have no effect |
| Define the genetic code Universal ` | The same codon codes for the same amino acids in all organisms this is why the genetic code is described |
| What is the advantage of universal | This means that genetic engineering is possible |
| Define what is non overlapping | Each base in a gene is only part of one triplet that codes for one amino acid. Therefore each codon or triplet of bases is read as a discrete unit |
| Why is non overlapping a advantage | This is an advantage as if a point mutation occurs it will only affect one codon and therefore one amino acid. |
| What is a intron | These are sections of DNA that do not code for amino acids. Introns are found in eukaryotic DNA but not in prokaryotic DNA. These get removed spliced out of mRNA molecules |
| What are exons | Exons are the sections of DNA that do code for amino acids |
| Differences between genome and proteome | The genome is an organisms complete set of DNA in one cell Proteome is the full range of proteins in one cell The genome should never change The proteome of the cell is constantly changing depending on which proteins are currently needed |