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CMN 572 Test 3
| Question | Answer |
|---|---|
| GLP-1 medication that lowers blood glucose, reduces appetite and suppresses appetite. | Semaglutide (Ozempic) |
| Long-acting insulin with an onset of 2-3 hours and duration of 24+ hours. | Lantus (Glargine) |
| Long-acting insulin with an onset of 1 hour and duration of 18-24 hours. | Levemir |
| Long-acting insulin with an onset of 30-90 mins and duration of 42+ hours | Tresiba |
| Side effects of Semaglutide | N/V/D |
| Biguanide medication that inhibits Vitamin B12 | Metformin |
| Side effects of Actos | Weight gain, bladder cancer, edema and anemia |
| Rapid-acting insulins: Novolog/Humalog | Onset of 10-15 mins, peak in 1-2 hours, duration 3-5 hours |
| TSH normal range | 0.4-4.0mIU/L |
| Complications of DM | Neuropathy, retinopathy and nephropathy |
| Which is a true statement regarding gynecomastia in boys? a. It is very uncommon b. It usually resolves in 2 years c. It is more common in females | b. It usually resolves in 2 years |
| Which of the following is a physical finding of hypothyroidism? a. bradycardia b. tachycardia c.hyperreflexive DTR's | a. bradycardia |
| Which diabetic medication aids in CV disease? | SGLT-2 Inhibitor: Empagliflozin (Jardiance 10-25mg q morning) |
| A1C target goal for T2DM | <7.0% |
| 1. Which of the following is the drug of choice for maintenance in Addison’s Disease a. Propanolol b. PTU c. Hydrocortisone | c. Hydrocortisone |
| 3. Which of the following is a long-acting insulin? a. Januvia (sitagliptin) b. Trulicity (dulaglutide) c. Lantus | c. Lantus |
| Increase in TSH, decrease in T4 | Hypothyroidism |
| Decrease in TSH, increase in T3, increase in T4 | Hyperthyroidism |
| Which injectables are non-insulins? | Trulicity, Victoza, Ozempic, Mounjaro |
| 2. Which is true regarding ozempic (semaglutide)? a. Common reaction nausea, vomiting and diarrhea b. GLP-1 receptor agonist c. Both are correct | c. Both are correct |
| 4. Which medication is held with a CT scan with contrast a. Metforman (glucophage) b. Actos (pioglitzone c. hydrocortisone | a. Metformin (glucophage) |
| TSH > 4.0mIU/L, normal T4, asymptomatic | Subclinical hypothyroidism |
| Most common cause of Hypothyroidism in the US | Hashimoto’s (autoimmune) thyroiditis |
| Affects females 5-8x more than males, especially women > 40 | Hypothyroidism |
| 5.Which is true regarding farxiga? a. It is approved for T1DM b. It is a sodium-glucose co-transporter 2 inhibitor c. It decreases thyroxine | b. It is a sodium-glucose co-transporter 2 inhibitor |
| What is the best screening test for hypothyroidism and hyperthyroidism? | TSH |
| 6. First-line medication for hypothyroidism? a. Levothyroxine (synthroid) b. Methimazole (tapazole) c. amiodarone | a. Levothyroxine |
| 7. Which of the following statement is true regarding TSH (thyroid stimulating hormone) a. TSH is elevated in hypothyroidism b. TSH is normal in hypothyoidism c. TSH is decreased in hypothyroidism | a. TSH is elevated in hypothyroidism |
| 9. According to ADA guidelines, which would be an acceptable fasting blood glucose level for a non-pregnant adult with diabetes? a. 168 b. 115 c. 194 | b. 115 |
| Lab values for prediabetes | AIC 5.7-6.4 Fasting plasma glucose 100-125mg/dL 2hr plasma glucose during 75g OGTT 140-199mg/dL |
| Features of Diabetes Insipidus? | Polyuria, polydipsia, dehydration, low BP |
| What is the initial dose of Levothyroxine (Synthroid)? | 25-50mcg/d |
| If TSH remains elevated after beginning treatment for hypothyroidism, should you increase or decrease the medication dose? | Decrease medication dose |
| Most common in women 20s-40s | Grave’s Disease |
| Clinical manisfestations of hyperthyroidism | Weight loss, palpitations, nervousnesss, heat intolerance, brittle nails, amenorrhea, loose stools, sweating, a-fib, exophthalmos, hyperreflexia |
| Clinical manifestations of hypothyroidism | Weight gain, depression, muscle cramps, constipation, cold intolerance, Raynaud’s Syndrome, goiter, bradycardia, hyporeflexive DTR, coarse, thinning hair |
| Treatment for hyperthyroidism , 60mg once or twice daily,max 320mg/day | Propranolol ER |
| Hyperthyroidism treatment, 300-600mg/day QID, favored for pregnancy and breastfeeding | PTU |
| Hyperthyroidism treatment, 30-60mg/day, preferred if receiving Iodine tx, must d/c 4 days prior to treatment, associated with birth defects | Tapazole |
| Most commonly due to excessive doses of corticosteroids | Cushings Syndrome (Hypercortisolism) |
| Clinical manifestations of Cushings Syndrome | Central obesity, “moon” face, buffalo hump |
| Diagnostic test for Cushings Syndrome | Dexamethasone suppression test |
| Clinical manifestations of Addisons Disease | Bronze pigmentation of skin, weight loss, hypoglycemia, fatigue |
| This lab is not useful in the diagnosis of hypothyroidism | T3 |
| This lab is not useful in the diagnosis of hypothyroidism | T3 |