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Nerve Impulse
| Question | Answer |
|---|---|
| Describe what is meant by the resting membrane potential. | No net flow of ions across the membrane. |
| Define an action potential. | Wave of electrical excitation along a neuron’s plasma membrane. |
| State the effect of depolarisation on the membrane potential. | more positive value inside neurone |
| Describe what happens to the membrane potential during repolarisation. | more negative value inside neurone |
| Define what is meant by a nerve impulse in terms of the membrane potential | Change in the membrane potential of the neurone’s plasma membrane resulting in depolarisation. |
| State one way of degrading neurotransmitters in the synapse | enzymes OR reuptake protein into presynaptic neuron. |
| Explain why it is necessary to degrade neurotransmitters in the synapse. | Prevents continual stimulation of nerve impulse by neurotransmitter degradation. |
| Step the order of channel proteins involved in a nerve impulse. | 1. Ligand gated Na channel 2. Voltage gated Na channel 3. Voltage gated K channel. |
| Which two channels contribute to depolarisation. | 1. Ligand gated Na channel 2. Voltage gated Na channel |
| Which channel protein contributes to repolarisation. | Voltage gated K channel |
| State the first step in nerve transmission following release of neurotransmitter into the synapse. | Neurotransmitters bind to their ligand gated channel on post synaptic membrane |
| Describe the result of a neurotransmitter binding to its ligand gated channel. | This causes an influx of positive Na ions into cell. |
| State what is required for voltage gated Na channels to open. | Sufficient Na ion movement into neurone OR membrane depolarised beyond threshold value |
| State what type of Na channel is responsible for the large rapid depolarisation of the membrane. | Voltage gated Na channel |
| State what type of channel causes repolarisation of the membrane potential. | Voltage gated K channels. |
| State how the ion concentration gradients are restored following repolarisation. | Na/K pump |
| Name the ion and the direction of movement that causes depolarisation in a nerve impulse. | Na ions entering the cell. |
| Name the ion and the direction of movement that causes repolarisation in a nerve impulse. | K ions leaving the cell. |