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Stem cell HH
learn about stem cells
| Question | Answer |
|---|---|
| Are stem cells specialised or unspecialised | unspecialised (undifferentiated) |
| State the two roles of stem cells. | 1. self renewal of more stem cells 2. differentiation to produce specialised cells |
| Name the process where stem cells make more stem cells | self renewal/mitosis |
| Name the process by which stem cells make specialised cells. | differentiation |
| Define differentiation (2 marks) | Certain genes are turned ON and other genes are turned off (1 mark) To produce specific proteins of that cell type (1 mark) |
| Name the two forms of stem cells | 1. embryonic 2, tissue stem cells |
| Give two examples of tissue stem cells | 1,. liver 2. muscle 3. heart 4. bone marrow |
| State the role of tissue stem cells | Growth/repair/replacement of cells. |
| Which type of stem cell is multipotent | Tissue |
| Explain what is meant by a pluripotent cell. | Can differentiate into ANY cell type. |
| Which type of stem cell is pluripotent | Embryonic stem cell |
| Describe an ethical issue with embryonic stem cell research. | Destroys the embryo |
| Describe an advantage of embryonic stem cell research | 1. may offer cures to incurable disease 2. avoids animal testing |
| If a stem cell makes specialised cells of many different tissues is the stem cell a)pluripotent b) multipotent pluripotent | |
| If a stem cell makes only a few types of specialised cells of one tissue the stem cell is said to be a) pluripotent b) multipotent | multipotent |
| Using model cells to study disease is an example of a A) therapeutic use b) research use | research use |
| Using stem cells in corneal transplants is an example of a A) therapeutic use b) research use | therapeutic use |
| Using stem cells as model cells in drug testing is an example of a A) therapeutic use b) research use | research use |
| Using stem cells in skin grafts is an example of a A) therapeutic use b) research use | therapeutic use |
| Using stem cells in bone marrow transplants is an example of a A) therapeutic use b) research use | therapeutic use |
| Using stem cells to study cell growth or differentiation is an example of A) therapeutic use b) research use | research use |
| Somatic stem cells undergo what process (es) | mitosis only |
| Germline stem cells undergo what processes | mitosis AND meiosis |
| Name the type of cell division where gametes are made by germline cells. | meiosis |
| Name the type of cell division by which germline stems self renew. | mitsosi |
| Are haploid or diploid cells made in mitosis | diploid. |
| Are haploid or diploid cells made in meiosis | haploid |
| Are gametes haploid or diploid | haploid |
| Are germline cells haploid or diploid | diploid |
| Name the female and male germline cells. | female = ovaries male = testes |
| Another term for a body cell like the liver cells is a) somatic b) germline | somatic |
| Are somatic cells haploid or diploid | diploid |
| In tumour formation excessive cell division is caused by | failure to respond to regulatory signals |
| In tumour formation cell division is a) too high b) too low | too high |
| The term for a mass of abnormal cells is a | tumour |
| What causes a tumour at a secondary site | tumour cells failing to adhere together and spreading to another organ |
| Explain the importance of differentiation. | Saves energy as only turn ON genes that are needed to express specific proteins |
| State the number of PAIRS of homologous chromosomes in diploid cells. | 23 |
| Describe what the first meiotic division separates. | homologous chromosomes |
| Describe what the second meiotic division separates | chromatids |
| State the number of chromosomes in haploid cells. | 23 |
| Cells not involved in reproduction are termed | somatic cells. |