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Pain/Heme/Onc 2

Pain, Hematology and Oncology 2

GenericBrandPharmacologic CategoryCommon IndicationsKey Side EffectsUS Boxed WarningsOther Notes
hydrocodone and acetaminophen (PO) Lortab, Vicodin, Norco Opioid and nonopioid analgesic combination Pain dizziness, drowsiness, nausea, vomiting, constipation, pruritus, respiratory depression (dose-related) risk of addiction, abuse/misuse, neonatal induced w/drawl syndrome; concomitant w/benzos, alcohol (CNS depressants) lead to profound sedation, respiratory depression, and death
oxycodone and acetaminophen (PO) Percocet, Endocet, Roxicet Opioid and nonopioid analgesic combination Pain dizziness, drowsiness, nausea, vomiting, constipation, pruritus, respiratory depression (dose-related) risk of addiction, abuse/misuse, neonatal induced w/drawl syndrome; concomitant w/benzos, alcohol (CNS depressants) lead to profound sedation, respiratory depression, and death; CYP3A4i can inc [Oxy]; hepatotoxicity
codeine and acetaminophen (PO) Tylenol with Codeine #3, Tylenol with Codeine #4 Opioid and nonopioid analgesic combination Pain dizziness, drowsiness, nausea, vomiting, constipation, pruritus, respiratory depression (dose-related) risk of addiction, abuse/misuse, neonatal induced w/drawl syndrome; concomitant w/benzos, alcohol (CNS depressants) lead to profound sedation, respiratory depression, and death
naloxone (IV, IM, SQ, intranasal) Narcan Opioid antagonist Opioid overdose opioid withdrawal syndrome in opioid-dependent populations, pain potentially life-threatening respiratory depression (when combined with other CNS and respiratory depressants); addition of naloxone to buprenorphine reduces possibility of parenteral misuse by producing opioid withdrawal symptoms when injected
buprenorphine and naloxone (SL) Suboxone Partial opioid agonist and opioid antagonist Opioid use disorder headache, opioid withdrawal syndrome in opioid-dependent populations, pain, diaphoresis, constipation potentially life-threatening respiratory depression (when combined with other CNS and respiratory depressants); addition of naloxone to buprenorphine reduces possibility of parenteral misuse by producing opioid withdrawal symptoms when injected
ferrous sulfate (PO) * FeroSul, SlowFe Iron supplement Iron deficiency anemia nausea, stomach upset, constipation (dose-related), dark and tarry stools Accidental overdose of iron is leading cause of fatal poisoning in children under 6 years old
cyanocobalamin (vitamin B12) (PO, IM, SL, intranasal) * --- Water-soluble vitamin Vitamin B12 deficiency (manifests as macrocytic anemia)
folic acid (PO) * --- Water-soluble vitamin Folic acid deficiency (manifests as macrocytic anemia), prevention of neural tube defects in pregnancy
Created by: Jimmy57J
 

 



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