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Neuro/Psych 3

Neurological and Psychiatric Disease 3

GenericBrandPharmacologic CategoryCommon IndicationKey Side EffectsUS Boxed WarningsOther Notes
lithium (PO) Lithobid Antimanic agent Bipolar disorder tremor, acne, hypothyroidism, weight gain, polyuria, polydipsia ability to promptly monitor levels is necessary narrow therapeutic index drug (toxicity may occur at concentrations close to therapeutic range; therapeutic drug monitoring is recommended)
sumatriptan (PO, intranasal, SQ) Imitrex Antimigraine Migraine fatigue, somnolence, dizziness, chest tightness CI in ischemic heart disease, history of stroke or TIA, peripheral vascular disease, and uncontrolled hypertension
haloperidol (PO, IV, IM) Haldol First-generation antipsychotic Schizophrenia sedation, EPS, parkinsonism, xerostomia, orthostatic hypotension, weight gain, QTc prolongation elderly patients with dementia-related psychosis treated with antipsychotic drugs at increased risk of death
clozapine (PO) Clozaril Second-generation antipsychotic Treatment-resistant schizophrenia sedation, xerostomia, urinary retention, constipation, orthostatic hypotension, sialorrhea, hyperglycemia, weight gain may cause severe neutropenia, orthostatic hypotension, bradycardia, & syncope, seizures, fatal myocarditis & cardiomyopathy; elderly patients with dementia-related psychosis treated with antipsychotic drugs at increased risk of death risk of neutropenia requires monitoring of absolute neutrophil count (ANC) to receive prescription
aripiprazole (PO, IM) Abilify Second-generation antipsychotic Schizophrenia, bipolar disorder, MDD (adjunct to antidepressants) akathisia, restlessness, sedation, EPS, xerostomia, urinary retention, constipation, orthostatic hypotension antidepressants increase the risk of suicidal thinking and behavior in children, adolescents and young adults; elderly patients with dementia-related psychosis treated with antipsychotic drugs at increased risk of death
quetiapine (PO) Seroquel, Seroquel XR Second-generation antipsychotic Schizophrenia, bipolar disorder, MDD (adjunct to antidepressants) sedation, EPS, xerostomia, urinary retention, constipation, orthostatic hypotension antidepressants increase the risk of suicidal thinking and behavior in children, adolescents and young adults; elderly patients with dementia-related psychosis treated with antipsychotic drugs at increased risk of death
olanzapine (PO, IM) Zyprexa Second-generation antipsychotic Schizophrenia, bipolar disorder, MDD (adjunct to antidepressants) sedation, EPS, xerostomia, urinary retention, constipation, orthostatic hypotension, weight gain elderly patients with dementia-related psychosis treated with antipsychotic drugs at increased risk of death
risperidone (PO, IM) PO: Risperdal IM: Risperdal Consta Second-generation antipsychotic Schizophrenia sedation, EPS, xerostomia, urinary retention, constipation, orthostatic hypotension, weight gain elderly patients with dementia-related psychosis treated with antipsychotic drugs at increased risk of death
rizatriptan (PO) Maxalt Antimigraine Migraine fatigue, somnolence, dizziness, chest tightness CI in ischemic heart disease, history of stroke or TIA, peripheral vascular disease, and uncontrolled hypertension
lurasidone (PO) Latuda Second-generation antipsychotic Schizophrenia, bipolar disorder, MDD (adjunct to antidepressants) sedation, EPS, xerostomia, urinary retention, constipation, orthostatic hypotension, weight gain antidepressants increase the risk of suicidal thinking and behavior in children, adolescents and young adults; elderly patients with dementia-related psychosis treated with antipsychotic drugs at increased risk of death CI with strong 3A4 inhibitors and inducers
Created by: Jimmy57J
 

 



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