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Endo 1
Endo 1 (Endocrine 1)
| Generic | Brand | Pharmacologic Category | Common Indication | Key Side Effects | US Boxed Warnings | Other Notes |
|---|---|---|---|---|---|---|
| empagliflozin (PO) | Jardiance | Sodium-glucose cotransporter inhibitor 2 (SGLT2 inhibitor) | Type 2 DM, HF, CKD | genital mycotic infections, UTI | ||
| metformin (PO) | Glumetza, Fortamet | Biguanide | Type 2 DM, PCOS | diarrhea, nausea, vomiting, Vitamin B12 defeciency | lactic acidosis | CI eGFR<30 |
| sitagliptin (PO) | Januvia, Zituvio | Dipeptidyl peptidase (DPP-4) inhibitor | Type 2 DM | headache, nasopharyngitis | ||
| glimepiride (PO) | Amaryl | Sulfonylurea | Type 2 DM | hypoglycemia, weight gain | ||
| glipizide (PO) | Glucotrol, Glucotrol XL | Sulfonylurea | Type 2 DM | hypoglycemia, weight gain | ||
| pioglitazone (PO) | Actos | Thiazolidinedione (TZD) | Type 2 DM | edema, weight gain, upper respiratory tract infection | may exacerbate congestive heart failure and CI in NYHA Class III and IV | |
| liraglutide (SQ) | Victoza, Saxenda | Glucagon-like peptide-1 (GLP-1) receptor agonist | Type 2 DM, chronic weight management | nausea, vomiting, diarrhea, constipation | may increase risk of thyroid c-cell tumor | |
| insulin glargine (SQ) | Lantus, Toujeo, Basaglar | Insulin, long acting | Type 1 DM, type 2 DM | hypoglycemia, weight gain | ||
| insulin NPH (SQ) | Humulin N, Novolin N | Insulin, intermediate acting | Type 1 DM, type 2 DM | hypoglycemia, weight gain | ||
| insulin aspart (SQ) | Novolog | Insulin, rapid acting | Type 1 DM, type 2 DM | hypoglycemia, weight gain | ||
| insulin lispro (SQ) | Humalog | Insulin, rapid acting | Type 1 DM, type 2 DM | hypoglycemia, weight gain | ||
| insulin regular (SQ, IV) | Humulin R, Novolin R | Insulin, short-acting | Type 1 DM, type 2 DM, DKA | hypoglycemia, weight gain | ||
| dapagliflozin (PO) | Farxiga | Sodium-glucose cotransporter inhibitor 2 (SGLT2 inhibitor) | Type 2 DM, HF, CKD | genital mycotic infections, UTI | ||
| dulaglutide (SQ) | Trulicity | Glucagon-like peptide-1 (GLP-1) receptor agonist | Type 2 DM | nausea, vomiting, diarrhea, pancreatitis | may increase risk of thyroid c-cell tumor | |
| semaglutide (PO, SQ) | SQ: Ozempic, Wegovy PO: Rybelsus | Glucagon-like peptide-1 (GLP-1) receptor agonist | Type 2 DM, chronic weight management | nausea, vomiting, diarrhea, constipation, pancreatitis | may increase risk of thyroid c-cell tumor, CI in personal of family history of medullary thyroid cancer | |
| tirzepatide (SQ) | Mounjaro, Zepbound | Dual GLP-1 and glucose-dependent insulinotropic polypeptide (GIP) agonist | Type 2 DM, chronic weight management | nausea, vomiting, diarrhea, constipation, increased heart rate, pancreatitis | may increase risk of thyroid c-cell tumor |
Created by:
Jimmy57J