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ID 4

ID 4 (Infectious Diseases 4)

GenericBrandPharmacologic CategoryCommon IndicationKey Side EffectsUS Boxed WarningsOther Notes
terbinafine (PO, topical *) Lamisil Allylamine antifungal Onychomycosis nausea, abdominal pain, diarrhea, elevated hepatic transaminases, headache
acyclovir (PO, IV) Zovirax Antiviral Herpes simplex virus nausea, increased hepatic transaminases, crystalluria vesicant
valacyclovir (PO) Valtrex Antiviral Herpes simplex virus nausea, increased hepatic transaminases
fluconazole (PO, IV) Diflucan Azole antifungal Vulvovaginal candidiasis, oropharyngeal candidiasis nausea, abdominal pain, diarrhea, QTc prolongation, elevated hepatic transaminases
ketoconazole (PO, topical *) Nizoral Azole antifungal Fungal infections nausea, abdominal pain, diarrhea, QTc prolongation, increased hepatic transaminases serious hepatotoxicity, including cases with a fatal outcome or requiring liver transplantation, have occurred; may cause QTc prolongation and drug interactions leading to QTc prolongation
oseltamivir (PO) Tamiflu Neuraminidase inhibitor antiviral Influenza nausea, vomiting, neuropsychiatric events (i.e., confusion, delirium, hallucinations) in pediatric patients (rare)
nystatin (PO) --------- Polyene antifungal Oropharyngeal candidiasis no major side effects
nystatin (topical) Nystop Polyene antifungal Cutaneous and mucocutaneous fungal infections burning, itching only use oral solutions for thrush
micafungin (IV) Mycamine Echinocandin antifungal Invasive candidiasis no major side effects
betamethasone and clotrimazole (topical) Lotrisone Glucocorticoid and azole antifungal Cutaneous fungal infections burning, itching, dryness, skin atrophy do not use for diaper dermatitis; adrenal suppression with long-term use over large areas of skin
nirmatrelvir + ritonavir (PO) Paxlovid Antiviral COVID-19 diarrhea, dysgeusia significant drug interactions; strong CYP3A4 inhibitor
remdesivir (IV) Veklury Antiviral COVID-19 hyperglycemia, renal impairment
emtricitabine + tenofovir disoproxil fumarate (PO) Truvada Nucleoside/Nucleotide Reverse Transcriptase Inhibitor (NRTI) HIV, PreP, PEP decreased bone mineral density, kidney injury, nausea, diarrhea post treatment acute exacerbation of hepatitis B, risk of drug resistance with use for preexposure prophylaxis
Emtricitabine (NRTI) + tenofovir alafenamide (NRTI) + bictegravir (INSTI) (PO Biktarvy Nucleoside/Nucleotide Reverse Transcriptase Inhibitor (NRTI) and Integrase Strand Transfer Inhibitor (INSTI) HIV increased serum bilirubin, headache, weight gain, insomnia, diarrhea, nausea post treatment acute exacerbation of hepatitis B take oral INSTI’s 2 hours before or 6 hours after products containing calcium, aluminum, magnesium, or iron
Created by: Jimmy57J
 

 



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