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ID 2
ID 2 (Infectious Diseases 2)
| Generic | Brand | Pharmacologic Category | Common Indications | Activity Against | Key Side Effects | US Boxed Warnings | Other Notes |
|---|---|---|---|---|---|---|---|
| meropenem (IV) | Merrem | Carbapenem | DFI, IAI, Meningitis, HAP | Pseudomonas aeruginosa, ESBL-producing Enterobacteriaceae | diarrhea, hypersensitivity reactions, seizures with excessive doses | ||
| ertapenem (IV) | Invanz | Carbapenem | DFI, IAI | ESBL-producing Enterobacteriaceae | diarrhea, hypersensitivity reactions, seizures with excessive doses | ||
| ciprofloxacin (PO, IV) | Cipro | Fluoroquinolone antibiotic | Pyelonephritis, HAP, VAP | Pseudomonas aeruginosa, atypicals, Enterobacteriaceae | QTc prolongation, tendon rupture, increased hepatic transaminases, photosensitivity | may cause serious adverse reactions including tendinitis and tendon rupture, peripheral neuropathy, and CNS effects; may exacerbate muscle weakness in patients with myasthenia gravis | take 2hr before or 6hr after products with divalent/trivalent cations:dairy products, calcium-fortified juices, multivitamins, mineral supplements; increased risk of aortic dissection or rupture, dysglycemias, CNS side effects: disorientation/delirium |
| levofloxacin (PO, IV) | Levaquin | Fluoroquinolone antibiotic | Pyelonephritis, HAP, VAP, CAP | Pseudomonas aeruginosa, Streptococcus pneumoniae, atypicals, Enterobacteriaceae | QTc prolongation, tendon rupture, increased hepatic transaminases, photosensitivity | may cause serious adverse reactions including tendinitis and tendon rupture, peripheral neuropathy, and CNS effects; may exacerbate muscle weakness in patients with myasthenia gravis | take 2hr before or 6hr after products with divalent/trivalent cations:dairy products, calcium-fortified juices, multivitamins, mineral supplements; increased risk of aortic dissection or rupture, dysglycemias, CNS side effects: disorientation/delirium |
| moxifloxacin (ophthalmic, PO, IV) | Ophthalmic: Vigamox, PO, IV: Avelox | Fluoroquinolone antibiotic | Ophthalmic: bacterial conjunctivitis, PO, IV: CAP | Streptococcus pneumoniae, atypicals, tuberculosis | QTc prolongation, tendon rupture, increased hepatic transaminases, photosensitivity | may cause serious adverse reactions including tendinitis and tendon rupture, peripheral neuropathy, and CNS effects; may exacerbate muscle weakness in patients with myasthenia gravis | take 2hr before or 6hr after products with divalent/trivalent cations:dairy products, calcium-fortified juices, multivitamins, mineral supplements; increased risk of aortic dissection or rupture, dysglycemias, CNS side effects: disorientation/delirium |
| azithromycin (PO, IV) | Zithromax, Z-Pak, Zmax | Macrolide antibiotic | CAP | Chlamydia trachomatis, atypicals | diarrhea, QTc prolongation | ||
| fidaxomicin (PO) | Dificid | Macrolide antibiotic | CDI | Clostridioides difficile | nausea | do not use for systemic infections (no systemic absorption) | |
| doxycycline (PO, IV) | Vibramycin | Tetracycline antibiotic | SSTI, CAP, tickborne diseases | MRSA, atypicals | esophagitis, photosensitivity | may cause permanent gray-brown discoloration of teeth and/or enamel hypoplasia when given to children; take 2hr before or 6hr after products containing divalent/trivalent cations:dairy products, calcium-fortified juices, multivitamins, mineral supplements | |
| minocycline (PO, IV) | Minocin | Tetracycline antibiotic | SSTI, acne | MRSA | photosensitivity, DILE | may cause permanent gray-brown discoloration of teeth and/or enamel hypoplasia when given to children; take 2hr before or 6hr after products containing divalent/trivalent cations:dairy products, calcium-fortified juices, multivitamins, mineral supplements |