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CV 4
CV 4 (Cardiovascular Disease 4)
| Generic | Brand | Pharmacologic Category | Common Indications | Key Side Effects | US Boxed Warnings | Other Notes |
|---|---|---|---|---|---|---|
| amiodarone (PO, IV) | Pacerone, Nexterone | Antiarrhythmic | AF (rhythm control), ventricular fibrillation (VF), ventricular tachycardia (VT) | hypothyroidism, hyperthyroidism, pulmonary toxicity, hepatotoxicity | life-threatening arrhythmias, pulmonary toxicity, hepatotoxicity | many drug interactions |
| ezetimibe (PO) | Zetia | Cholesterol absorption inhibitor | Dyslipidemia | diarrhea | ||
| fenofibrate (PO) | Tricor, Trilipix | Fibric acid derivative | Hypertriglyceridemia | dyspepsia, myopathy/rhabdomyolysis, elevated hepatic transaminases | ||
| gemfibrozil (PO) | Lopid | Fibric acid derivative | Hypertriglyceridemia | dyspepsia, myopathy/rhabdomyolysis, elevated hepatic transaminases | ||
| atorvastatin (PO) | Lipitor | HMG-CoA reductase inhibitor | Dyslipidemia, CAD, stroke | myopathy/rhabdomyolysis | avoid excessive grapefruit juice intake, avoid in pregnancy and breastfeeding | |
| lovastatin (PO) | Altoprev | HMG-CoA reductase inhibitor | Dyslipidemia, CAD, stroke | myopathy/rhabdomyolysis | avoid excessive grapefruit juice intake, avoid in pregnancy and breastfeeding | |
| pravastatin (PO) | Pravachol | HMG-CoA reductase inhibitor | Dyslipidemia, CAD, stroke | myopathy/rhabdomyolysis | avoid excessive grapefruit juice intake, avoid in pregnancy and breastfeeding | |
| rosuvastatin (PO) | Crestor | HMG-CoA reductase inhibitor | Dyslipidemia, CAD, stroke | myopathy/rhabdomyolysis | avoid excessive grapefruit juice intake, avoid in pregnancy and breastfeeding | |
| simvastatin (PO) | Zocor | HMG-CoA reductase inhibitor | Dyslipidemia, CAD, stroke | myopathy/rhabdomyolysis | avoid excessive grapefruit juice intake, avoid in pregnancy and breastfeeding | |
| omega-3 ethyl esters (PO)* | Lovaza | Omega-3 fatty acids | Hypertriglyceridemia | dyspepsia, eructation, fishy aftertaste | can prolong bleeding time when used with other medication that can increase bleeding risk, use caution with fish/shellfish allergy | |
| icosapent ethyl (PO)* | Vascepa | Omega-3 fatty acids | Hypertriglyceridemia | eructation, arthralgia | can prolong bleeding time when used with other medication that can increase bleeding risk, use caution with fish/shellfish allergy |