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Module 4 & 5
Advanced pathophysiology
| QuestionMonocytes that migrate | Answer |
|---|---|
| macrophages | Monocytes that migrate from the blood into tissues are called ____These cells are of central importance in initiating inflammation and recruitment of other leukocytes to areas of need. _ . |
| Autoimmunity is a failure of self-tolerance | true |
| Activation of the complement cascade by the classical pathway begins with | C1 binding to the antigen antibody complex |
| A person with type B blood | A person with type B blood has B antigens and anti-A antibodies, thus they will react with a Type II hypersensitivity reaction if given A blood. |
| The body’s inflammatory response is always the same, regardless of cause. | This is true: increased permeability, recruitment and emigration of leukocytes, and phagocytosis of antigens and debris. |
| The geriatric population is more vulnerable to disease due to | Decreased ability to respond to new antigens |
| Activated kinins cause | Vasodilation vascular permeability and pain |
| The coagulation cascade is linked to the complement and kinin systems by activated factor X. | False. The coagulation cascade is linked to the complement and kinin systems by activated factor XII (Hageman factor). |
| Cells that display normal __________ on their cell surfaces are protected from natural killer (NK) cell cytotoxicity. | major histocompatability complex |
| Natural killer cells and phagocytic cells are mediators of innate defenses. | I |