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Chapter 16 Concepts
| Question | Answer |
|---|---|
| 1. What cells make up the mononuclear phagocytic system? | Monocytes & macrophages 644 |
| 2. Virus-infected cells release what | Interferons. 644 |
| 3. What type of phagocytic cells are circulating in the blood? What cells function as phagocytes | Monocytes & neutrophils. 644 |
| 4. What is the effect of interleukin-1 secretion? | Fever 647 |
| 5. Mucus, tears, saliva, and hair are all examples of what type of defense against potential pathogens? | Mechanical barriers 643 |
| 6. What defense mechanism responds to the presence of foreign antigens by initiating a cascade of reactions, resulting in inflammation and enhanced phagocytosis in the area? | Complement system 655 |
| 7. Discuss responses to a pathogen are slow and fast | Fast: innate immune response; slow: adaptive immune response. 642 |
| 8. Discuss innate and adaptive immune response? | Innate: immediate, nonspecific defense; adaptive: slower, specific response. 643 |
| 9. Following a tissue transplant, discuss patient requirements and advocacy | Typically need to take medications to surppress their immune system Immunosuppressive drugs; 659 |
| 10. What cell types are primarily responsible for immunity? | Lymphocytes and macrophages |
| 11. T lymphocytes are responsible for what aspect of defense against infection? | Cellular immune response |
| 12. What type of immunoglobulin is the most abundant of the circulating antibodies? | Immunoglobulin G (IgG). 661 |
| 13. What type of immune resistance will a person develop after contracting and fighting off an infection? | Naturally acquired active immunity 663 |
| 14. What is the target of cytotoxic T cells? | Cancer cells & virally infected cells |
| 15. How do cytotoxic T cells destroy their targeted cells? | by releasing perforin which puts holes in the cell membranes of the targeted cells 645 |
| 16. How can newborns can be protected against certain digestive and respiratory infections ? | When they receive IgA via their mothers milk |
| 17. Antigen-presenting cells engulf and digest an antigen, then insert antigen fragments on their cell surfaces in association with__________. | Class 2 MHC proteins |
| 18. Rheumatic fever, Graves' disease, and systemic lupus erythematosus are examples of | Autoimmune disorders. 654 |
| 19. What is the relationship between antigens and antibodies? | The presence of an antigen triggers the production of antibodies 652 |
| 20. What is the function of plasma cells? | To produce antibody molecules 644 |
| 21. What occurs during a primary immune response? | The plasma antibody concentration increases, peaking at about 10-12 days after exposure to antigen 657 |
| 22. What is the result of a cellular immune response? | T cells attach directly to the cells displaying foreign antigens and destroy them |
| 23. How does a vaccine produce its effects? | By stimulating a primary immune response 648 |
| 24. Following contact with its targeted antigen, a B cell will divide and differentiate into__________ which produce and secrete antibodies. | Plasma cells. 637 |
| 25. Antibody actions against antigens include__________ in which the antibodies bind to antigen, forming an insoluble complex that can be phagocytized. | Precipitation 636 |
| 27. If a vaccine is given to most people in a population, it can halt the spread of an infection because of__________. | Herd immunity. 665 |
| 28. When does aging of the lymphatic system begin? | Before birth 656 |
| 29. What part of an antibody molecule binds to its targeted antigen? | The ends of the molecule consisting of both light and heavy chain variable regions 638 |
| 30. Anaphylactic shock is a risk with what type of hypersensitivity? | Type I hypersensitivity |
| 31. What are pathogens | Disease-causing agents 635 |
| 32. What is the role of lymphatic system in body fluids | Moves excess tissue fluid from the interstitium to the bloodstream 664 |
| 33. What are the structures of lymphatic vessels | Most similar to a vein 666 |
| 34. The flow of lymph from collecting ducts | Lymph enters the vein and becomes apart of the plasma 666 |
| 35. Where would we see increase/decrease in lymph formation | Increased hydrostatic pressure in tissue fluid 638 |
| 36. How does lymph differ from plasma | Lymph contains only WBC & plasma contains RBC & WBC 658 |
| 37. List the functions of the lymphatic system | Transporting the products of lipid digestion from the intestine to the liver, protecting the body organs from infection, returning interstitial fluid to the bloodstream 661 |
| 38. Tissue fluid is formed when? | When fluid is forced out of blood plasma |
| 39. Lymph is formed when? | When fluid enters lymph capillaries |
| 40. Region of a lymph node through which blood vessels and nerves pass is called | Hilum. 637 |
| 41. Cervical lymph nodes filter how? | Drains upper limb to the mammary gland 650 |
| 42. Describe the function and characteristics of the spleen | It resembles a large lymph node divided into lobules & can filter blood |
| 43. Which hormones stimulate T lymphocytes | Thymosin 659 |
| 44. How can innate and adaptive defenses be characterized | Innate: Nonspecific and fast; Adaptive: specific and slow |
| 45. Redness and swelling how it affects injured tissue/infection | Increased blood flow and capillary permeability 643 |
| 46. How does antibody molecule bind to its targeted antigen | Complementary shapes in variable regions. 655 |
| 47. What happens with anaphylactic shock | causes type 1 hypersensitivity; severe allergic reaction 641 |
| 48. How do viruses differ from other pathogens | They are not capable of reproducing outside a living cell; requiring host |