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Chapter 16 Concepts

QuestionAnswer
1. What cells make up the mononuclear phagocytic system? Monocytes & macrophages 644
2. Virus-infected cells release what Interferons. 644
3. What type of phagocytic cells are circulating in the blood? What cells function as phagocytes Monocytes & neutrophils. 644
4. What is the effect of interleukin-1 secretion? Fever 647
5. Mucus, tears, saliva, and hair are all examples of what type of defense against potential pathogens? Mechanical barriers 643
6. What defense mechanism responds to the presence of foreign antigens by initiating a cascade of reactions, resulting in inflammation and enhanced phagocytosis in the area? Complement system 655
7. Discuss responses to a pathogen are slow and fast Fast: innate immune response; slow: adaptive immune response. 642
8. Discuss innate and adaptive immune response? Innate: immediate, nonspecific defense; adaptive: slower, specific response. 643
9. Following a tissue transplant, discuss patient requirements and advocacy Typically need to take medications to surppress their immune system Immunosuppressive drugs; 659
10. What cell types are primarily responsible for immunity? Lymphocytes and macrophages
11. T lymphocytes are responsible for what aspect of defense against infection? Cellular immune response
12. What type of immunoglobulin is the most abundant of the circulating antibodies? Immunoglobulin G (IgG). 661
13. What type of immune resistance will a person develop after contracting and fighting off an infection? Naturally acquired active immunity 663
14. What is the target of cytotoxic T cells? Cancer cells & virally infected cells
15. How do cytotoxic T cells destroy their targeted cells? by releasing perforin which puts holes in the cell membranes of the targeted cells 645
16. How can newborns can be protected against certain digestive and respiratory infections ? When they receive IgA via their mothers milk
17. Antigen-presenting cells engulf and digest an antigen, then insert antigen fragments on their cell surfaces in association with__________. Class 2 MHC proteins
18. Rheumatic fever, Graves' disease, and systemic lupus erythematosus are examples of Autoimmune disorders. 654
19. What is the relationship between antigens and antibodies? The presence of an antigen triggers the production of antibodies 652
20. What is the function of plasma cells? To produce antibody molecules 644
21. What occurs during a primary immune response? The plasma antibody concentration increases, peaking at about 10-12 days after exposure to antigen 657
22. What is the result of a cellular immune response? T cells attach directly to the cells displaying foreign antigens and destroy them
23. How does a vaccine produce its effects? By stimulating a primary immune response 648
24. Following contact with its targeted antigen, a B cell will divide and differentiate into__________ which produce and secrete antibodies. Plasma cells. 637
25. Antibody actions against antigens include__________ in which the antibodies bind to antigen, forming an insoluble complex that can be phagocytized. Precipitation 636
27. If a vaccine is given to most people in a population, it can halt the spread of an infection because of__________. Herd immunity. 665
28. When does aging of the lymphatic system begin? Before birth 656
29. What part of an antibody molecule binds to its targeted antigen? The ends of the molecule consisting of both light and heavy chain variable regions 638
30. Anaphylactic shock is a risk with what type of hypersensitivity? Type I hypersensitivity
31. What are pathogens Disease-causing agents 635
32. What is the role of lymphatic system in body fluids Moves excess tissue fluid from the interstitium to the bloodstream 664
33. What are the structures of lymphatic vessels Most similar to a vein 666
34. The flow of lymph from collecting ducts Lymph enters the vein and becomes apart of the plasma 666
35. Where would we see increase/decrease in lymph formation Increased hydrostatic pressure in tissue fluid 638
36. How does lymph differ from plasma Lymph contains only WBC & plasma contains RBC & WBC 658
37. List the functions of the lymphatic system Transporting the products of lipid digestion from the intestine to the liver, protecting the body organs from infection, returning interstitial fluid to the bloodstream 661
38. Tissue fluid is formed when? When fluid is forced out of blood plasma
39. Lymph is formed when? When fluid enters lymph capillaries
40. Region of a lymph node through which blood vessels and nerves pass is called Hilum. 637
41. Cervical lymph nodes filter how? Drains upper limb to the mammary gland 650
42. Describe the function and characteristics of the spleen It resembles a large lymph node divided into lobules & can filter blood
43. Which hormones stimulate T lymphocytes Thymosin 659
44. How can innate and adaptive defenses be characterized Innate: Nonspecific and fast; Adaptive: specific and slow
45. Redness and swelling how it affects injured tissue/infection Increased blood flow and capillary permeability 643
46. How does antibody molecule bind to its targeted antigen Complementary shapes in variable regions. 655
47. What happens with anaphylactic shock causes type 1 hypersensitivity; severe allergic reaction 641
48. How do viruses differ from other pathogens They are not capable of reproducing outside a living cell; requiring host
 



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