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GI 2
| Generic | Brand | Pharmacologic Category | Common Indication | Key Side Effects | Boxed Warnings | Other Notes |
|---|---|---|---|---|---|---|
| famotidine (PO, IV) | Pepcid | H2 blocker | GERD, erosive esophagitis, SUP | HA, constipation, D/, mental status changes | --- | --- |
| dexlansoprazole (PO) | Dexilant | PPI | GERD, PUD, erosive esophagitis, SUP | abd pain, N/, bone fracture, vitamin B12 deficiency, hypomagnesemia | increased risk of C. diff infection | --- |
| esomeprazole (PO, IV) | Nexium | PPI | GERD, PUD, erosive esophagitis, SUP | abd pain, N/, bone fracture, vitamin B12 deficiency, hypomagnesemia | increased risk of C. diff infection | --- |
| lansoprazole (PO, IV) | Prevacid | PPI | GERD, PUD, erosive esophagitis, SUP | abd pain, N/, bone fracture, vitamin B12 deficiency, hypomagnesemia | increased risk of C. diff infection | --- |
| omeprazole (PO) | Prilosec | PPI | GERD, PUD, erosive esophagitis, SUP | abd pain, N/, bone fracture, vitamin B12 deficiency, hypomagnesemia | increased risk of C. diff infection | --- |
| pantoprazole (PO, IV) | Protonix | PPI | GERD, PUD, erosive esophagitis, SUP | abd pain, N/, bone fracture, vitamin B12 deficiency, hypomagnesemia | increased risk of C. diff infection | --- |
| sucralfate (PO) | Carafate | GI protectant | PUD | constipation, bezoar formation | --- | --- |
| metoclopromide (PO, IV) | Reglan | D2 antag. | Gastroparesis, GERD, N/V | drowsiness, dystonia, akathisia, EPS, QTc, /D, hyperprolactinemia | tardive dyskinesia, DNU >12 weeks | CI w/ obstruction, perforation, hemorrhage |
| ondansetron (PO, IV) | Zofran | Selective 5-HT3 antag. | N/V | HA, fatigue, constipation, QTc | --- | --- |
| promethazine (PO,IM, IV, PR) | Phenergan | H1 antag. | Motion sickness, N/V | drowsiness, dry mouth, blurred vision, QTc, EPS | respiratory depression <2yo, can cause peripheral extravasation | --- |
| meclizine (PO) | Bonine | H1 antag. | Motion sickness, vertigo | drowsiness, dry mouth, blurred vision | --- | --- |
| diphenoxylate and atropine (PO) | Lomotil | Antidiarrheal | Diarrhea | N/, confusion, drowsiness, dizziness, xerostomia, tachycardia, urinary retention | --- | DNU for infectious diarrhea, DNU peds <6 |