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EAS

The different reactants and products of electrophilic aromatic substitution

TermDefinition
Nitration (NO2) HNO3, H2SO4
NH2 --> Amide acyl halide, pyridine
Sulfonation (HSO3) SO3, H2SO4
Halogenation X2, FeX3
NO2 --> NH2 Sn / HCl
Friedel-Crafts acylation acyl chloride + AlCl3
Friedel-Craft alkylation alkyl chloride + AlCl3
NH2 --> amide anhydride
amide --> NH2 NaOH
OH --> ester acyl halide
ketone --> OH NaOH
Diazonium salt formation (N(triple)N) HNO2 + H3O (only works on NH2)
DZS --> Cl CuCl
DZS --> Br CuBr
DZS --> cyano group (CN) CuCN
DZS --> I KI
DZS --> OH H2SO4, H2O, heat
DZS --> F HBF4, heat
DZS --> H (removal of substituent group) H3PO2
HSO3 --> H (removal of HSO3) H2O, heat
aldehyde / ketone --> H (removal) NH2-NH2 / KOH
Created by: ddaniel728
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