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Med Tech chpt. 8
| Question | Answer |
|---|---|
| A systemic effect occurs | Throughout the body via the blood |
| Which is an enteral route of administration? | Oral |
| Orally administered drugs can be lost (i.e., not reach the systemic circulation) by which mechanism (3)? | Degration due to stomach acidity, first-pass matabolism retarded dissolution |
| Which dosage form does not have a disintigration and dissolution step as part of its oral absorption process? | Oral solutions |
| _______ tablets are placed under the tongue | Sublingual |
| which nonaqueous oral solution has 10 grams of drug per 100mL of solution? | potent tincture |
| Which is a disadvantage of an oral suspension formulation? | Unpleasant oral texture |
| Which is an "Injection independant" parenteral route of administration? | Inhalation |
| Which injectable route is the most rapid acting? | Intravenous |
| syringability refers to the properties of a suspension while being_______ | Drawn from a container into a syringe |
| while intravenous (IV) administration device would be appropriate to inject a small volume of medication (e.g., 5mL) over 1-2 minutes | Syringe and needle |
| When an antibiotic injection is given in a small volume of solution that is connected to a main IV fluid bag, this is known as an | IV piggyback |
| Which listing of parenteral routes is the expected order of absorption rates from fastest to slowest | IV>IM>SC |
| Needles for intramuscular injection are generally _____ inches long and _____ G | 1 to 1.5, 19-22 |
| When considering subcutaneous (SC) administration, which listing is the expected order of absorption rates from fastest to slowest | IM>SC>Oral |
| Co-administering epinephrine with subcutaneously (SC) administered drug is ecpected to ____ | decreas regional blood flow and decrease the subcutaneous absorption of the drug |
| The usual site for an intradermal injection is the | anterior surface of the forearm |
| What percentage is an administered opthalmic dose is lost due to spillage from the eye? | 80% |
| Systemic absorption of a drug administered as an opthalmic formulation can occur when____ | the drug is absorbed through the conjunctiva |
| when untranassaly adminitering a drug with an MDI aerosol, ____ | breath in as the MDI is actuated |
| A drug administered by inhalation using a medtered dose inhaler(MDI) areosol. Which pathway withh the drug follow? | Mouth, Trachea, bronchioles, alveoli |
| What size particle is expected to reach the alveolar sacs after inhalation administration? | 0.6 micron |
| What dermal formulation is a suspension? | lotions |
| Glycerinated gelatin is the preferred vaginal suppository base because it______ | Dissolves slowly in vaginal mucus secretions |
| intrauterine devices (IUDs) provide long term_____ | contraception protection |
| (T or F) A syrup is an oral dosage for caracterized by high sucrose content | T |
| (T or F) A spirit is an alcoholic or hydroalcoholic solution of volatile substances | T |
| (T or F) An oral liquid formulation where one liquid is dispersed throughout another liquid in the form os small droplets is called emulsion | T |
| (T or F)A gel is a unit dosage form for sublingual administration | F |
| (T or F)Thrombus can occur if excess air is injected into the veins | F |
| (T or F) injectability refers to the properties of a suspension while being injected | T |
| (T or F)A hematoma can result at one site if intramuscular (IM) sites of an injection are not changed or rotated | T |
| (T or F)A scar is produced at the site of an intradermal (ID) injection | F |
| (T or F) The average drop size of an eyedropper is 50 microliters which is the same as the average tear volume of the eye | F |
| (T or F) When inhaling a drug in an MDI areosol, shake the areosol before use | T |
| the ______ in the barrier to drug absorption after dermal administration | Stratum corneum |
| Particles the size of _____ microns are expected to reach the alveolar sacs after inhalation administration | 0.6 |
| An oral formulation where the drug does not completely dissolve in the solvent is called a/an _____ | suspension |
| the tear colume in the eye turns over about every _______ minutes | 2-3 |
| intradermal injections are generally administered in the ______ | anterior surface of the forearm |
| The maximum fluid volume that can be subcutaneously injected in _____ mL | 2 |
| The alcoholic content of the most common elixers ranges between ___% and _____% | 5%-40% |
| _____ form three-dimensional network of particles that restrict the movement of the solvent | Gels |
| Rectal suppositories can sooth inflammed hemorrhoidal tissues or | Laxatation |
| Insulin is usually administered by ______ injection in the home setting | subcutaneous |