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Cardio 3

GenericBrandPharmacologic CategoryCommon IndicationKey Side EffectsBoxed WarningsOther Notes
dabigatran (PO) Pradaxa Anticoagulant, direct thrombin inhibitor AF (stroke prevention), VTE bleeding, dyspepsia premature stopping ↑thrombotic events; ↑epidural or spinal hematoma in pt undergoing spinal puncture swallow whole, dispense and store in original packaging, discard after 4 months
apixaban (PO) Eliquis Anticoagulant, factor Xa inhibitor AF (stroke prevention), VTE bleeding premature stopping ↑thrombotic events; ↑epidural or spinal hematoma in pt undergoing spinal puncture ---
rivaroxaban (PO) Xarelto Anticoagulant, factor Xa inhibitor AF (stroke prevention), VTE, PAD bleeding premature stopping ↑thrombotic events; ↑epidural or spinal hematoma in pt undergoing spinal puncture ---
warfarin (PO) Coumadin, Jantoven Anticoagulant, vitamin K antagonist AF (stroke prevention), VTE bleeding bleeding risk narrow TI; monitoring recommended, dose dependent tablet colors, vit. K intake recommended, many DDIs
enoxaparin (SQ) Lovenox Anticoagulant, low molecular weight heparin ACS, VTE bleeding, hyperkalemia, HIT ↑epidural or spinal hematoma in pt undergoing spinal puncture do not expel air bubble from syringe prior to injection
heparin (IV, SQ) --- Anticoagulant ACS, VTE bleeding, hyperkalemia, HIT --- ---
clopidogrel Plavix Antiplatelet agent CAD, stroke bleeding diminished effectiveness in poor metabolizers ---
ticagrelor (PO) Brilinta Antiplatelet agent ACS bleeding, dyspnea sometimes fatal bleeding, DNE mg ASA daily due to reduced effectiveness ---
aspirin (PO) Bayer, Bufferin, Ecotrin Antiplatelet agent ACS, stable angina, pain, stroke dyspnea, heartburn, bleeding --- CI w/ allergy, Reye's syndrome in <18; tinnitus w/ OD
nitroglycerin (SL) Nitrostat Vasodilator ACS, stable angina HA, flushing, syncope, dizziness --- DNU w/ PDE-5 inhibs, tachyphylaxis; can aggrevate angina by hypertrophic cardiomyopathy
alteplase (intracatheter, IV) Cathflo (intracatheter), Activase (IV) Fibrinolytic Catheter clearance (intracatheter), STEMI, ischemic stroke, PE (IV) bleeding --- CI in pts w/ severe uncontrolled HTN
Created by: aarel01
 

 



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