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MSK

GenericBrandPharmacologic CategoryCommon IndicationKey Side EffectsBoxed WarningsOther Notes
tizanidine (PO) Zanaflex a2 agonist Spasticity drowsiness, hypotension, dizziness, xerostomia, weakness --- ---
hydroxychloroquine (PO) Plaquenil Aminoquinolone RA, SLE, malaria /D, retinal toxicity, rash --- associated w/ cardiomyopathy, BMS, QT prolongation, and neuromuscular effects
colchicine (PO) Colcrys Antigout agent Gout N/V/D, BMS, myopathy (including rhabdomyolysis) --- ---
diclofenac (PO) Voltaren NSAID OA, RA, acute pain N/D, dyspepsia, abd pain, flatulence ↑CV thrombotic effects, MI, and stroke; ↑GI ADRs, e.g. ulceration, bleeding, perforation ↓renal blood flow and compromise existing renal fxn (renal disease, HF, cirrhosis)
ibuprofen (PO) Motrin, Advil NSAID OA, RA, acute pain N/D, dyspepsia, abd pain, flatulence ↑CV thrombotic effects, MI, and stroke; ↑GI ADRs, e.g. ulceration, bleeding, perforation ↓renal blood flow and compromise existing renal fxn (renal disease, HF, cirrhosis)
meloxicam (PO) Mobic NSAID OA, RA, acute pain N/D, dyspepsia, abd pain, flatulence ↑CV thrombotic effects, MI, and stroke; ↑GI ADRs, e.g. ulceration, bleeding, perforation ↓renal blood flow and compromise existing renal fxn (renal disease, HF, cirrhosis)
indomethacin (PO) Indocin NSAID OA, RA, acute pain, gout N/D, dyspepsia, abd pain, flatulence ↑CV thrombotic effects, MI, and stroke; ↑GI ADRs, e.g. ulceration, bleeding, perforation ↓renal blood flow and compromise existing renal fxn (renal disease, HF, cirrhosis)
naproxen (PO) Naprosyn, Anaprox, Aleve NSAID OA, RA, acute pain, gout N/D, dyspepsia, abd pain, flatulence ↑CV thrombotic effects, MI, and stroke; ↑GI ADRs, e.g. ulceration, bleeding, perforation ↓renal blood flow and compromise existing renal fxn (renal disease, HF, cirrhosis)
ketorolac (PO, IV) Toradol NSAID Pain N/D, dyspepsia, abd pain, flatulence ↑CV thrombotic effects, MI, and stroke; ↑GI ADRs, e.g. ulceration, bleeding, perforation ↓renal blood flow and compromise existing renal fxn (renal disease, HF, cirrhosis)
celecoxib (PO) Celebrex NSAID, COX-2 selective OA, RA, acute pain N/D, dyspepsia, abd pain, flatulence ↑CV thrombotic effects, MI, and stroke; ↑GI ADRs, e.g. ulceration, bleeding, perforation ↓renal blood flow and compromise existing renal fxn (renal disease, HF, cirrhosis)
diclofenac (topical) Voltaren Gel NSAID OA, RA, acute pain pruritis, rash --- ---
cyclobenzaprine (PO) Flexiril, Amrix, Fexmid MSK relaxant Muscle Spasm drowsiness, dizziness, xerostomia, fatigue --- use may cause prolonged cardiac arrhythmias and tachycardia
baclofen (PO) --- MSK relaxant Spasticity drowsiness --- ---
methocarbamol (PO) Robaxin MSK relaxant Muscle Spasm drowsiness --- ---
lidocaine (transdermal, IV) Lidoderm (transdermal), Xylocaine (IV) Topical analgesic (transdermal), antiarrhythmic (IV) Pain (transdermal), ventricular arrhythmias (IV) (transdermal): dermatitis, erythema, urticaria, skin depigmentation, skin edema (IV): bradycardia --- patch 12 hours on 12 hours off; patch may be cut
allopurinol (PO) Zyloprim XO inhib. Gout N/D, rash, leukopenia, thrombocytopenia --- rare risk with severe (maybe fatal) allopurinol hypersensitivity syndrome (Asian populations)
succinylcholine (IV) Anectine Depolarizing neuromuscular blocking agent Neuromuscular blockade for intubation procedures hyperkalemia, myalgia, malignant hyperthermia (rare) acute rhabdo and hyperkalemia → cardiac arrest and death in peds w/ undiagnosed skeletal muscle disease ---
etanercept (SQ) Enbrel Anti-TNF-a inhib. RA infection, j-site rxn, HA, N/ serious infections, malignancies such as lymphomas ---
adalimumab (SQ) Humira Anti-TNF-a inhib. RA, CD/UC infection, j-site rxn, HA, N/ infection, injection site reaction, HA, N/ ---
Created by: aarel01
 

 



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