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DRUG ICARDS

Metoprolol

QuestionAnswer
Mechanism of action Metoprolol is an immediate release beta blocker. It antagonises beta 1 receptors in the heart causing a decrease in the heart rate, cardiac output and blood pressure
Indications -Adults with moderate cardiovascular compromise as a result of atrial fibrillation, where the ventricular rate is predominantly greater than 130 BPM
Contraindications (2) -Known severe allergy -Hypotension. Metoprolol will further reduce the blood pressure
Cautions (6) - First degree heart block - Known sick sinus syndrome without internal pm - Previous second or third degree heart block without internal pm - Asthma or COPD. - Heart failure - Pregnancy
Use in pregnancy -Safety has not been demonstrated, must seek clinical advice -May be administered if the patient is breatfeeding
Dosage 25mg
administration Onset Duration usual preparation PO 10-20 mins 4-6 hrs 50 mg tablets
Pharmacokinetics - Metoprolol is absorbed within the gastrointestinal tract and metabolised in the liver - There are no significant effects from liver impairment on acute administration
Common interactions -The blood pressure effect will be potentiated by other medicines that lower the heart rate or lower blood pressure
Additional information - Patients with chronic or paroxysmal atrial fibrilation/atrial flutter may be prescribed a beta blocker. Personnel should still administer metoprolol as indicated, even if the patient has taken their own beta blocker
Created by: nicolaprice01
 

 



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