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CNS 3
| Generic Name | Brand Name | Pharmacology Category | Common Indications | Side Effects |
|---|---|---|---|---|
| lithium (PO) | Lithobid | Antimanic agent | Bipolar disorder | tremor, acne, hypothyroidism, weight gain, polyuria, polydipsia US Boxed Warning: ability to promptly monitor levels is necessary |
| sumatriptan (PO, intranasal, SQ) | Imitrex | Antimigraine | Migraine | fatigue, somnolence, dizziness, chest tightness Other Notes: CI in ischemic heart disease |
| haloperidol (PO, IV, IM) | Haldol | First generation antipsychotic | Schizophrenia | sedation, EPS, parkinsonism, xerostomia, orthostatic hypotension, weight gain, QTc prolongation US Boxed Warning: elderly patients with dementia-related psychosis treated with antipsychotic drugs at increased risk of death |
| clozapine (PO) | Clozaril | Second generation antipsychotic | Treatment resistant schizophrenia | sedation, xerostomia, urinary retention, constipation, orthostatic hypotension, sialorrhea, hyperglycemia, weight gain US Boxed Warning: may cause neutropenia |
| aripiprazole (PO, IM) | PO/IM: Abilify, IM: Aristada | Second generation antipsychotic | Schizophrenia, bipolar disorder, MDD, (adjunct to antidepressants) | sedation, EPS, xerostomia, urinary retention, constipation, orthostatic hypotension US Boxed Warning: antidepressants increase the risk of suicidal thinking and behavior in children |
| quetiapine (PO) | Seroquel, Seroquel XR | Second generation antipsychotic | Schizophrenia, bipolar disorder, MDD, (adjunct to antidepressants) | sedation, EPS, xerostomia, urinary retention, constipation, orthostatic hypotension US Boxed Warning: antidepressants increase the risk of suicidal thinking and behavior in children |
| olanzapine (PO, IM) | Zyprexa | Second generation antipsychotic | Schizophrenia, bipolar disorder, MDD, (adjunct to antidepressants) | sedation, EPS, xerostomia, urinary retention, constipation, orthostatic hypotension, weight gain US Boxed Warnings: elderly patients with dementia-related psychosis treated with antipsychotic drugs at increased risk of death |
| risperidone (PO, IM) | PO: Risperdal, IM: Risperdal Consta | Second generation antipsychotic | Schizophrenia | sedation, EPS, xerostomia, urinary retention, constipation, orthostatic hypotension, weight gain US Boxed Warnings: elderly patients with dementia-related psychosis treated with antipsychotic drugs at increased risk of death |
| rizatriptan (PO) | Maxalt | Antimigraine | Migraine | fatigue, somnolence, dizziness, chest tightness Other Notes: CI in ischemic heart disease |
| lurasidone (PO) | Latuda | Second generation antipsychotic | Schizophrenia, bipolar disorder, MDD, (adjunct to antidepressants) | sedation, EPS, constipation, orthostatic hypotension, weight gain Boxed Warning: Increased risk of suicidal ideation Other Notes: CI with strong CYP3A4 inhibitors and inducers |