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infectious diseases
animal health W8
| Question | Answer |
|---|---|
| infection | Invasion and multiplication of micro-organisms in body tissues |
| casual agents | • Normally grouped according to aetiological agents e.g. bacterial, viral ect • Not all microorganisms are pathogenic • Some are commensals • Symbiotic • Many are free living |
| pathogen - | microorganism capable of causing disease |
| infectious disease - | diseased caused by biological agent |
| contagious - | an infectious disease that is spread from one animal to another |
| resident microflora | • many microorganisms are useful • Also known as commensals • They live on + within the body and usually cause no harm • Prevent the colonisation of more harmful microorganisms • May provide service to the host e.g fermentation of fibre in the gut |
| non contagious diseases | not all diseases are passes onto other individuals commensals (often bacteria) may gain advantage in the affected host + cause disease |
| non contagious diseases | • Cat bite abscesses • Wound infections • Bacterial skin infection (pyoderma) • Bladder infection (bacterial cystitis) |
| in order for pathogens to trigger disease they will need to - | • Penetrate the hosts defences (through physical barriers) • Multiply within the host • Overcome the hosts initial defences (through the innate immunity) • Cause harm to the host |
| when pathogens cause harm to the host this is when | clinical signs |
| the capacity of an infection to cause disease is determined by | 1. The infective dose 2. The virulence of the agent 3. The susceptibility of the host |
| the hosts susceptibility may be increased | • Age : very young or very old • Stress • Pre-existing disease • Genetic predisposition • Immunosuppression • Drug administration – can increase or decrease • Nutritional status |
| based on the balance between the infectivity of the pathogen and the hosts susceptibility there are a number of outcomes | • The immune system wins! • Subclinical infection may occur • The pathogen wins and the patient loses = DISEASE |
| the defence system - | - urine - gastric PH - commensal bacteria - integument - self cleansing processes |
| transmission - | is defined as the transfer of an infection from one animal to another |
| direct transmission - | pathogens spread via direct contact particularly important for pathogens that are fragile and do not survive in the environment - bites, scratches, grooming and licking |
| indirect transmission | mechanical vectors also known as fomites, some pathogens can survive on inanimate objects and be passes around in the enviromet |
| biological vectors are organisms that | carry infections agents from one host to another the pathogen becomes infective (develops and multiplies) within the vector before infecting the final host |
| indirect transmission - vehicles of transmission - Substances that are normally taken in by the body but pathogens may have attached to them | • Water – may be contaminated by faeces or urine • Air – may be contaminated by airborne pathogens • Food – may be contaminated by faeces |
| horizontal transmission | - The disease is spread to other members of the same species e.g covid 19 large groups of animals or humans |
| transmission may occur at several stages of the disease process | • During the incubation period • During the time the animal is showing clinical signs |
| after the animal has partially or fully recovered vertical transmission - | • Dam to offspring • If the Dam is infected at the time of conception or during pregnancy. • In utero or via the colostrum • Disease is passed from one generation to the next |
| what does carriers mean | this means the animal may continue to shed infective agents following recovery despite showing minimal or no signs of disease |
| carriers | • Convalescent carriers • Healthy carriers • Most commonly shed during periods of stress • Continuous excreters • Intermittent excreters |
| preventative methods that can be put in place to reduce the risk of disease transmission | • Disinfection and cleaning protocols • Careful and correct waste disposal • Good personal hygiene • Isolation, barrier nursing and quarantine • Good husbandry • Controlling disease vectors • Vaccination • education • PPE |