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BioChemistry ETC
College Biochemistry ETC Spring 2023 UML
| Question | Answer |
|---|---|
| Complex III | oxidizes CoQ and reduces cytochrome c (reductase) |
| cytochrome c | transfers electrons from Complex III to Complex IV |
| Complex IV | transfers electrons from cytochrome c to O2 |
| Complex I | accepts electrons from NADH and reduces Coenzyme Q (UQ) |
| What enters Complex I? | NADH from inside the mitochondria |
| Complex II | succinate dehydrogenase and reduces coenzyme Q |
| Coenzyme Q | accepts electrons from Complex I and II |
| flavoprotein | Complex I |
| What pathway does NADH take to get to O2? | NADH to Complex I to Coenzyme Q to Complex III to cytochrome c to Complex IV to O2 to form H2O |
| What pathway does FADH@ take to get to O2? | FADH to Complex II to Coenzyme Q to Complex III to cytochrome c to Complex IV to O2 to form H2O |
| ATP Synthase | Proton gradient is used to synthesize ATP with this membrane protein |
| ATP Synthase Structure | composed of F1 and F0 units |
| F0 unit | a and b subunits anchor to membrane, subunit c makes a ring and is the rotor of the motor, proton flows through a-c causes c to rotate |
| F1 unit | alpha and beta subuinits form alternate pattern in the hexamer formed |
| F1 Hexamer | 6 ATP-binding sites with each site at the interface of adjacent subunits. |