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BioChemistry ETC

College Biochemistry ETC Spring 2023 UML

Complex III oxidizes CoQ and reduces cytochrome c (reductase)
cytochrome c transfers electrons from Complex III to Complex IV
Complex IV transfers electrons from cytochrome c to O2
Complex I accepts electrons from NADH and reduces Coenzyme Q (UQ)
What enters Complex I? NADH from inside the mitochondria
Complex II succinate dehydrogenase and reduces coenzyme Q
Coenzyme Q accepts electrons from Complex I and II
flavoprotein Complex I
What pathway does NADH take to get to O2? NADH to Complex I to Coenzyme Q to Complex III to cytochrome c to Complex IV to O2 to form H2O
What pathway does FADH@ take to get to O2? FADH to Complex II to Coenzyme Q to Complex III to cytochrome c to Complex IV to O2 to form H2O
ATP Synthase Proton gradient is used to synthesize ATP with this membrane protein
ATP Synthase Structure composed of F1 and F0 units
F0 unit a and b subunits anchor to membrane, subunit c makes a ring and is the rotor of the motor, proton flows through a-c causes c to rotate
F1 unit alpha and beta subuinits form alternate pattern in the hexamer formed
F1 Hexamer 6 ATP-binding sites with each site at the interface of adjacent subunits.
Created by: ihipoli
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