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Pharm II W1
Histamineâ‚‚Blocker Therapy
| Question | Answer |
|---|---|
| Which conditions are histamine2 blockers used to treat? | Gastric ulcer, Duodenal ulcer, Gastroesophageal reflux disease |
| Which statement regarding the pharmacodynamics of cimetidine is accurate? | The elimination half-life of cimetidine is 1.5 to 2 hours. |
| Which statement regarding the pharmacokinetics of ranitidine is accurate? | The drug undergoes hepatic metabolism. |
| Which instructions would the nurse provide Mr. Evans about when to take the prescribed ranitidine? | Take it at bedtime, or after evening meal. |
| Before administering cimetidine to a 27-year-old female patient, which patient parameters would a nurse ensure have been assessed? | Hepatic function, Renal function, Pregnancy status, Fluid and electrolyte status |
| Which respiratory complication associated with cimetidine is a concern, as the drug increases gastric pH? | Pneumonia |
| Which effect would a nurse anticipate may occur if a patient taking phenytoin is given cimetidine? | Increased effect of phenytoin |
| With which medical condition would a nurse expect the health care provider to reduce the dosage of ranitidine due to potential accumulation of the drug? | Kidney disease |
| Which outcome is anticipated as a result of histamine2 receptor blockers obstructing histamine2 receptors in the parietal cells in the stomach? | Decrease in hydrogen ions and gastric acid |
| Which comparison between cimetidine and ranitidine is accurate? | Ranitidine is more potent than cimetidine. |
| Which patients would a nurse determine will likely receive a dosage reduction in cimetidine for gastroesophageal reflux disease? | A 71-year-old patient with hypertension A 58-year-old patient with chronic kidney disease |
| Which patients would a nurse recommend against use of ranitidine? | A patient who is breastfeeding A patient who is in her second trimester of pregnancy |
| Which effect would a nurse anticipate may occur if a patient with warfarin is given cimetidine? | Increased anticoagulant effect |
| Which teaching point will a nurse share with a 63-year-old male patient who has been prescribed ranitidine for gastroesophageal reflux disease (GERD)? | Ranitidine should be separated from any other drugs the patient may be taking by at least 1 hour |
| Which monitoring parameters would a nurse ensure are evaluated when a 73-year-old patient who is newly prescribed cimetidine returns for a follow-up? | Lung sounds Liver function Renal function Mental status change |