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Bio exam 4
| Question | Answer |
|---|---|
| prokaryotic genome | single celled organisms, one double stranded circular DNA molecule. Resides in the nucleoid |
| Eukaryotic genome | multicellular organisms, several linear double stranded DNA molecules in the form of chromosomes. Resides in the nucleus |
| chromosomes; linear chunks of DNA Genes; found on chromosomes codes for traits traits; what we see | distinguish between chromosomes, genes, and traits |
| describe the mechanisms of chromosome compaction | starts as double helix, wrapped around histone proteins to form a nucleosome, DNA condenses into chromatin, DNA is copied then condenses into chromosome for cell division, two identical chromatids called sister chromatids are formed |
| G1 Phase | first gap, cell is preparing |
| S phase | DNA synthesis, DNA is duplicated |
| G2 phase | energy is replenished, organelles reproduce and cytoskeleton break down |
| prometaphase | nuclear envelope fragments. microtubules begin to interact with chromosomes at kinetochore. protein complex that assemble on DNA at centromeres. |
| prophase | DNA condenses into chromosomes, mitotic spindle begins to form, structure made of microtubules and associated proteins, centrosomes move towards poles |
| metaphase | centrosomes are at opposite ends microtubules align chromosomes along the metaphase plate. no nuclear envelope |
| anaphase | microtubules contract (get smaller), separation of sister chromatids, each copy is pulled toward a separate pole (side of the cell), cell elongates, no nuclear envelope |
| telophase | nuclear envelope reforms, chromosomes decondense back to chromatin, spindle microtubules are gone. |
| cytokinesis in animals | actin filaments contract around the equator of the cell, constrict from outside in, forms two individual daughter cells |
| cytokinesis in plants | cell wall prevents constriction, cell wall materials are delivered to center of cell to form a cell plate, the plate grows to create two daughter cells |
| describe G0 | cell retirement, cell is alive but not dividing. enter G0 phase if it does not pass G1 checkpoint |
| internal mechanisms | protein regulators, negative/positive regulators |
| external mechanisms | growth factors, anchorage dependence, density dependent inhibition |
| G1 checkpoint | is the cell big enough |
| G2 checkpoint | were any mistakes made |
| M checkpoint | all chromosomes must be attached to spindle microtubules and at metaphase plate |
| protooncogenes + tumor suppressors | describe the molecules that control the cell cycle through positive and negative regulation |
| because checkpoints are not being checked causes tumors | Describe how cancer is caused by uncontrolled cell growth |
| makes proteins that inhibit cell division or cause apoptois | describe how tumor suppressors function |
| proto-oncogenes | make proteins that stimulate cell division advance the cell cylce |
| they don't suppress tumors, they don't check the cell | explain how mutant tumor suppressors cause cancer |
| Meiosis one | seperation of homolgous chromosomes |
| meiosis 2 | separation of sister chromatids |
| meiosis has homologos chromosomes, Meiosis is a process where a single cell divides twice to produce four cells containing half the original amount of genetic information. | explain the differences between meiosis and mitosis |
| crossing over, independent assortment, random fertilization | explain the mechanisms within the meiotic process that produce genetic variation among the haploid gametes |
| variation is good because we get new combos of alleles that increase survival and the ability to produce offspring | identify variation among offspring as a potential evolutionary advantage o sexual reproduction |
| diploid dominant, haploid dominant, alternation of generations | describe the three different life cycle types among sexually reproducing multicellular organisms |
| protein regulators | used to stop or start parts of the cell cycle |
| negative regulators | stop the advancement of the cell cycle |
| positive regulators | promote the advancement of the cell cycle |
| pedigree | a family tree that describes the interrelationships of parents and children across generations |
| square | male |
| shaded in square | affected male |
| circle | female |
| shaded in circle | affected female |
| diamond | gender unkown |
| slash through unshaded shape | dead male/femal |
| slash through shaded shape | affected dead male/female |