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Respiratory Drugs
MS1 Respiratory Drugs
| Question | Answer |
|---|---|
| Norepinephrine | |
| Epinephrine | Vasoconstriction for local anesthesiaControl of HemorrhageHemostasis During SurgeryStress Incontinence |
| Tyramine | Displaces NE from vessicles into synaptic cleft |
| Amphetamine | |
| Cocaine | Competative inhibitor of neuronal uptakeIncreases NE in synaptic cleft |
| Tricyclic Antidepressants- e.g. Imipramine, amitryptiline | Competative inhibitor of neuronal uptake |
| Reserpine | Inhibits neuronal uptake into synaptic vessicles - depletes NE |
| MAO inhibitors | First antidepressantsIncrease NE levels |
| COMT inhibitors | Inhibit Catechol-O-methyltransferaseUsed in therapy for Parkinson'sTolcapone-TasmarEntacapone |
| Isoproterenol | Bronchospasm (Beta 2) |
| Phenylephrine | alpha-receptor agonistDecongestion of mucous membranesHypotensionParoxysmal Atrial TachycardiaMydriasis |
| clonidine | HypertensionWithdrawal from addiction |
| Albuterol | Bronchospasm (beta 2 agonist)Short acting Beta-2 agonist |
| Salmeterol | Bronchospasm (beta 2 agonist)Long-acting Beta 2 agonist |
| Dobutamine | Acute Heart Failure |
| Dopamine | Circulatory Shock |
| Formoterol | Bronchospasm (beta-2 agonist)Long-acting Beta 2 agonist |
| Cromolyn | Bronchospasm (NSAID)Inhibits Mast Cell granulization |
| Montelukast (Singulair) | Leukotriene receptor antagonists |
| Zafirlukast (Accolate) | Leukotriene receptor antagonist |
| Zileuton (Zyflo) | 5-lopoxygenase inhibitor for maintenance therapy of asthma |
| Ipratropium (Atrovent) | muscarinic receptor antagonists |
| Tiatropium (Spiriva) | muscarinic receptor antagonists - Selectivity for M3 muscarinic receptor on bronchial smooth muscle |
| Prazosin | alpha-1 receptor agonist |
| Propranolol | Beta-1 and Beta-2 blocker |
| Pindolol | Competative Beta-1 antagonist (good for patients who need some sympathetic innervation of the heart) |
| Labetolol | Alpha-1, Beta 1, Beta 2 antagonist |
| Carvetolol (Coreg) | Alpha-1, Beta 1, Beta 2 antagonist |
| Sumatriptan | Migrane Medication |
| Terazosyn, Doxyzosyn, Tamsulosin | alpha-1 specific antagonists |