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pharmacology 2

Proton Pump Inhibitor Therapy

QuestionAnswer
Which statement by the nursing student about the mechanism of action of proton pump inhibitors (PPIs) requires further intervention? "PPIs work by blocking histamine2 receptors, which reduces gastric acid secretion."
In which time frame would a patient expect to experience effects from esomeprazole? 1 Hour
Which statement regarding the pharmacodynamic profile of omeprazole is accurate? The elimination half-life of omeprazole is 0.5 to 1 hour.
Which medical conditions would a nurse recognize that oral esomeprazole may be used to treat? Gastroesophageal reflux disease (GERD) Duodenal ulcers Nonsteroidal antiinflammatory drug (NSAID)-induced ulcers Zollinger-Ellison syndrome
Which patients would a nurse determine require cautious use of or avoidance of esomeprazole? A 70-year-old Asian patient with hypertension A 73-year-old Caucasian patient with osteoporosis A 29-year-old Hispanic patient who is breastfeeding A 54-year-old Caucasian patient with alcoholic cirrhosis
Which outcome would a nurse anticipate from the drug interaction that may occur in a patient who is receiving diazepam and has been newly prescribed omeprazole? Increase in serum concentration of diazepam
patient who is receiving omeprazole has been prescribed clopidogrel following stent placement. Which outcome does a nurse alert the health care provider about resulting from the drug interaction? Decrease in activation of clopidogrel
93yr-old patient with GERD is prescribed esomeprazole. The patient is immobile in a skilled nursing facility, is frail, and experienced a stroke a year ago. Which adverse effects of esomeprazole will the nurse be concerned about in this patient Dementia Pneumonia Osteoporosis Hip or vertebral fracture
Created by: colby.caswell
 

 



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