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pharmacology 2
Antiemetic Drug Therapy
| Question | Answer |
|---|---|
| Which antiemetic can a nurse anticipate having the longest duration of action? | Scopolamine |
| Which antiemetic is excreted in urine, feces, and bile? | Dronabinol |
| Which statement regarding the pharmacodynamic parameters of intravenous (IV) ondansetron is accurate? | Its elimination half-life is 3-5 hrs |
| Which time frame can a nurse expect dexamethasone to reach its peak concentration? | 5-10 minutes |
| Which statement regarding the pharmacokinetic parameters of aprepitant is accurate? | The drug undergoes metabolism mostly by CYP3A4 |
| Which phrase describes how ondansetron works to treat nausea and vomiting? | Blocks the serotonin receptors in the chemoreceptor trigger zone and vagal nerve terminals in the gastrointestinal (GI) tract |
| Which patients would a nurse determine cannot safely receive therapy with promethazine? | A 1-year-old child with profuse vomiting A 31-year-old patient who is breastfeeding |
| caring for patient who'll be using scopolamine patch for motion sickness. additional to scopolamine, patient taking diphenhydramine, an antihistamine, as needed for allergies. Which patient statement about scopolamine requires further intervention? | "I will apply the patch to my upper arm." |
| Which effect would a nurse anticipate might occur from the drug interaction between dronabinol and warfarin? | Increase in warfarin concentration |
| Which electrolyte abnormality would a nurse monitor for in a patient receiving dexamethasone as an antiemetic who is also receiving furosemide, a loop diuretic? | Hypokalemia |
| Which frequency would a nurse anticipate seeing promethazine prescribed for a patient with nausea and vomiting? | every 4-6 hours |
| Which explanation would a nurse provide a patient about the avoidance of alcohol while taking promethazine? | The combination may cause excessive central nervous system (CNS) effects such as sedation. |