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Chlamydia
MedMicro 2006 UTHSCmed
| Question | Answer |
|---|---|
| Chlamydia trachomatis Shapeq | Small bacillus |
| Chlamydia trachomatis Aerobicity | Aerobic |
| Chlamydia trachomatis Motility | nonmotile, no pili |
| Chlamydia trachomatis Pathophysiology | Life cycle: EB infects, RB divides |
| Chlamydia trachomatis reservoir | Humans |
| Chlamydia trachomatis Diseases | STD's, Trachoma (eyes), LGV, PID; cna be asymptomatic in women |
| Chlamydia trachomatis Specimen | Exudate |
| Chlamydia trachomatis Bab Diagnosis | giemsa stain, specific culture, DNA probe, serology, PCR (best one) |
| Chlamydia trachomatis Treatment | Azithromycin(one dose), doxycycline(2 wks), clarithromycin (kids, 95% efficacy), Erythromycin(neonates and children) |
| Chlamydia trachomatis Prevention/Control | Safe sex, screening, notify partners, abstinence |
| Chlamydia trachomatis NOTES: | Leading preventable cause of blindness, #1 STD in US, Obligate intracellular anaerobe, No peptidoglycan cell wall |
| C. psittaci Shape | Small bacillus |
| C. psittaci Aerobicity | Aerobic |
| C. psittaci Motility | Non-motile, no pili |
| C. psittaci Reservoir | Birds, animals |
| C. psittaci Diseases | Parrot fever, pneumonia, complications |
| C. psittaci Lab diagnosis | Giemsa stain, DNA prbe, PCR, serology |
| C. psittaci Treatment | Axithromycin, Doxycycline |
| C. psittaci Prevention | Care with bird wast |
| C. psittaci NOTES: | Obligate intracellular parasite, No peptidoglycan in cell wall |
| C. pneumoniae Shape | Small bacillus |
| C. pneumoniae Aerobicity | Aerobic |
| C. pneumoniae Motility | NON-motile, no pili |
| C. pneumoniae Reservoir | Humans |
| C. pneumoniae Diseases | Pneumonia, atherosclerosis |
| C. pneumoniae Lab Diagnosis | Giemsa stain, DNA probe, PCR, serology |
| C. pneumoniae Treatment | Axithromycin |
| C. pneumoniae NOTES: | Obligate intracellular parasite, No peptidoglycan in cell wall |
| Chlamydiae | Originally thought to be viruses, but are not: Gram (-) cell envelope, contain DNA and RNA, ribosomes, susceptible to antibiotics, make own proteins, nucleic acids, lipids |
| General Properties: Chlamydiae | Obligate intracellular parasites, Very small, Not culturable outside host cell, no peptidoglycan in the cell wall, NON-motile, nonpiliated, (All these same as viruses) |
| Why are Chlamydiae Bacteria? | Gram (-) cell envelope, has DNA & RNA, has prokaryotic ribosomes, Synthesizes its own protein, nucleic acids, lipids, Susceptible to several antibodies. |
| Why Chlamydiae and NOT Rickettsia? | No cytochromes, No ATP, Don't require arthropods for transmission |
| EB (elementary body) | Small(.2-.4 mM diameter), extracellular, metaboically inactive, cannot proliferate, infectious |
| RB (reticular body) | .6-1.0 mM diameter, intracellular, metabolically active, divides by binary fission, noninfectious |
Created by:
Garzilla