Help
Options
Didn't know it?
click below
click below
Knew it?
click below
click below
Don't Know
Remaining cards (0)
Know
retry
shuffle
restart
0:00
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.
Normal Size Small Size show me how
Normal Size Small Size show me how
Perio Module 6
Chapter 13 Host Immunoinflammatory Response to Biofilm
| Question | Answer |
|---|---|
| What are the phases of the bone remodeling cycle? | resorption phase, reversal phase, formation phase, resting phase |
| What do cytokines do? | Send macrophages to the site of infection, could initiate destruction and bone loss in chronic periodontitis, and attracts immune cells to an infection site by increasing vascular permeability |
| What would the first clinical sign of inflammation be if plaque biofilms are present near the gingival tissues? | Redness and swelling |
| Initiation of good patient self-care can result in a return to a healthy periodontium during which stages of disease progression? | initial, early and established lesions |
| In which phase of periodontal disease progression are macrophages first recruited to the gingival connective tissue? | early lesion |
| In which phase of periodontal disease progression are PMNs the most numerous cells at the site of the periodontal infection? | initial lesion |
| In which phase of periodontal disease progression does PGE2 and MMPs initiate collagen destruction but cause no bone destruction? | established lesion |
| In which phase of periodontal disease progression does PGE2 mediate bone destruction by stimulating large numbers of osteoclasts to resorb alveolar bone? | advanced lesion |
| In which phase of periodontal disease progression does RANKL/RANK/OPG pathway participate? | advanced lesion |
| In which phase of periodontal disease progression does the coronal-most portion of the junctional epithelium first detach from the tooth surface? | established lesion |
| In which phase of periodontal disease progression do the increasing numbers of PMNs rush to the site of the periodontal pathogens and in doing so destroy healthy gingival connective tissue? | early lesion |
| In which phase of periodontal disease progression do the PMNs first travel through the bloodstream, exit the bloodstream, and travel through the gingival connective tissue to the gingival sulcus? | initial lesion |
| What do matrix metalloproteinases' (MMPs) do? | Responsible for collagen destruction in periodontal tissue |
| What are osteoblasts? | Osteoblasts are cells that specialize in forming bone. |
| What are osteoclasts? | Osteoclasts are cells that create erosion cavities in the bone. |
| What can contribute to periodontal disease severity? | environmental factors |
| What causes periodontal disease? | periodontal pathogens along with the body's response to these pathogens |
| What do prostaglandins do? | Initiate alveolar bone destruction in periodontal disease |
| What is the resolution of inflammation and return to a noninflammatory state called? | catabasis |
| What can activity by the body's immune system can cause? | tissue destruction |
| How does the body's immune system immune system work? | it protects against invading microorganisms but it is different for every person and every infected area |
| What is the host response? | it is the way in which the body to respond to periodontal pathogens |
| What risk factor category does tobacco smoking fall under? | environmental factor |
| Which cytokines are involved in periodontal disease? | TNF-α, IL-1, IL-6, IL-8 |
| What causes most of the destruction of periodontal tissues? | Immune response to bacterial pathogens |
| What biochemical mediator causes extensive collagen destruction of the periodontal tissues? | Matrix metalloproteinases (MMPs) |
| Which biochemical mediator increases vascular permeability and has the potential to initiate the tissue destruction and bone loss seen in chronic periodontitis? | Cytokines |
| Which biochemical mediator plays the most important role in the bone destruction seen in periodontitis? | RANKL |
| Which phase of periodontal disease progression includes bacterial colonization near gingival margins? | Bacterial accumulation phase |
| When do levels of OPG decrease? | When the periodontium is inflamed |
Created by:
BrendaAlberts