Save
Upgrade to remove ads
Busy. Please wait.
Log in with Clever
or
show password
Forgot Password?
Don't have an account?  Sign up 
Sign up using Clever
or
Username is available taken
show password


Make sure to remember your password. If you forget it there is no way for StudyStack to send you a reset link. You would need to create a new account. Your email address is only used to allow you to reset your password. See our Privacy Policy and Terms of Service.

Already a StudyStack user? Log In

Reset Password
Enter the associated with your account, and we'll email you a link to reset your password.
focusNode
Didn't know it?
click below
 
Knew it?
click below
Don't Know
Remaining cards (0)
Know
0:00
edit
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.

  Normal Size     Small Size show me how

coagulation cascade

QuestionAnswer
Tissue factor binds with what activated clotting factor VIIa
VIIa/TF need what two cofactors Ca2+ and phospholipid
VIIa/TF, Ca2+ and phsopholipid can combine with what two clotting factors to produce activated clotting factors IX and XIa to make IXa or X and IXa to make Xa
IXa can activate what clotting factor Xa
XII requires what two cofactors to become activated High molecular weight kininogen and prekallikrein
XIIa uses high molecular weight kallikrein to activate what clotting factor XIa
Xa converts what clotting factor to active form without requiring cofactors VIII to VIIIa
Xa requires cofactors Ca2+ and phospholipid to convert what clotting factor to an active form VII to VIIa
Prothrombin requires what cofactor and what activated clotting factor to produce thrombin Phospholipid and Xa
What are the cofactors the clotting cascade requires in order to function Tissue factor, Ca2+, Phospholipid, Tissue factor, high-molecular weight kininogen and prekallikrein
Thrombin converts what clotting factor to its active form V to Va
Fibrinogen requires what to form a fibrin monomer Thrombin
Fibrin polymer requires what clotting factor to form crosslinked fibrin polymer XIIIa
XIII can be converted to an active form by what two methods 1. Thrombin 2. Xa
The coagulation cascade is initiated by what mechanism Tissue factor release at the site of injury
Tissue factor complexes with what factor at the site of injury Factor VIIa
Amplification of the clotting cascade involves what factors Thrombin: activates platelets and cofactors V and VII. VIIIa, Va, and IXa assemble on the surface of activated platelets
Propagation of the clot occurs via what process The complexes on activated platelets continue the cascade and prothrombinase converts PT to thrombin which converts fibrinogen to fibrin and then clot stabilization by polymerization of fibrin monomers
Created by: 746660120
 

 



Voices

Use these flashcards to help memorize information. Look at the large card and try to recall what is on the other side. Then click the card to flip it. If you knew the answer, click the green Know box. Otherwise, click the red Don't know box.

When you've placed seven or more cards in the Don't know box, click "retry" to try those cards again.

If you've accidentally put the card in the wrong box, just click on the card to take it out of the box.

You can also use your keyboard to move the cards as follows:

If you are logged in to your account, this website will remember which cards you know and don't know so that they are in the same box the next time you log in.

When you need a break, try one of the other activities listed below the flashcards like Matching, Snowman, or Hungry Bug. Although it may feel like you're playing a game, your brain is still making more connections with the information to help you out.

To see how well you know the information, try the Quiz or Test activity.

Pass complete!
"Know" box contains:
Time elapsed:
Retries:
restart all cards