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LIVER
| Term | Definition |
|---|---|
| Right Hepatic Vein | Separates right lobe in to Anterior and Posterior segments. - largest |
| Middle Hepatic Vein | Separates the Right and Left lobe of the liver - enters IVC |
| Left Hepatic Vein | Separates the left lobe in to Medial and Lateral segments - smallest |
| Falciform Ligament | Extends from the Umbilicus to the Diaphragm. - Attaches liver to the Anterior Abdominal wall and Diaphragm - SEPARATES Right and Left lobe Anteriorly |
| Ligamentum Teres | Obliterated remnant of the fetal umbilical vein - AKA Round Ligament - Suspended within the Falciform Ligament |
| Ligamentum Venosum | A remnant of the ductus venosus in fetal life - seen as an echogenic line separating the caudate lobe from the left lobe - shunts 1/2 of blood from umbilical vein to the IVC |
| Glissons Capsule | - Covers liver - Layer pf thick connective fibrous tissue - Also covers portal vessels |
| Not Covered in Peritoneum | - Bare area - Hilum (back side of port hepatis) - Gallbladder Fossae |
| Liver | - Intraperitoneal organ - Lies in left and right hypochondrium - BEST acoustic window |
| Mid-Clavicular | - Approximate length 15 - 17 cm |
| Right Lobe of Liver | - Largest Lobe - 3 Fossae: Porta hepatis, GB, IVC - Anatomically separated by the Falciform Ligament |
| Left Lobe of Liver | - Lies in epigastric & left hypochondrium - Always smaller than the RL |
| Caudate Lobe | - Posterior & Superior - Landmark for IVC and ligamentum venosum - right margin (process) extends in a tongue like projection - Has own blood supply |
| IVC | Cuts liver into right and left lobe - located at the posterior portion of the liver |
| Hepatic Veins | -Hepatofugal - Intersegmental & interlobar - NO bright walls - NO high amplitude reflections - ^ Increase in diameter towards diaphragm & IVC - Flow is dependent on activity of Right Atrium |
| Portal Triad | Sonographic "Mickey Mouse" Sign - Portal vein - Hepatic Artery - Common Hepatic Duct |
| Main enzyme of the liver: | Amylase - breaks down starches |
| Liver Functions | - Formation of Bile - Metabolism - Storage - Blood reservoir - Heat production - Detoxification |
| The Liver Excretes: | - Bilirubin - Cholesterol - Drugs - Hormones *Phagocytosis* |
| The Liver Stores: | - Glycogen/ Glucagon - Amino Acids - Fats - Vit. A, D, and B complex - Iron - Copper |
| The liver metabolizes: | - Carbohydrates - Lipids - Proteins |
| Formation of Bile: | 800-1,000 mL per 24 hours Secretes 1-2 L daily |
| AST - Aspartate Aminotransferase (SGOT) | Enzyme found in liver, muscles & TISSUES Increased levels = - Acute Hepatitis - Cirrhosis - Fatty Changes |
| ALT - Alanine Aminotransferase (SGPT) | More specific to the liver - produced in hepatocytes Increased levels = - Dead/ damaged Hepatocytes - Hepatitis - Jaundice - Hepatocellular disease - Biliary tract disease - Shock - Drug toxicity |
| ALP - Alkaline Phosphatase | Enzyme produced in bile ducts, kidneys, bones and intestines Increase levels = - Hepatocellular disease - Biliary obstruction |
| LDH - Lactic Acid Dehydrogenase | Found in ALL tissues - detects myocardial & pulmonary infarction - Elevated = Liver mass |
| Bilirubin | Product of breakdown of old RBC's that are converted to bile pigments - Elevated levels lead to Jaundice |
| Direct - Conjugated Bilirubin | Increase with biliary tract obstruction & hepatocellular disease |
| Indirect - Unconjugated Bilirubin | Increase with hepatocellular disease & disorders causing increase in RBC hemolysis |
| AFP - Alpha Fetal Protein | Antigen found in fetus - presents in more than 50% of patients with hepatomas & hepatoblastomas |
| Normal liver Findings: | - Homogeneous - Isoechoic OR hyperechoic to renal parenchyma - Smooth Contour |
| Diffuse (Parenchymal) | - Heterogeneous - Hepatocellular disease (disease that affects the hepatocytes & interferes w liver function) - Ranges from simple fat changes to hepatitis or cirrhosis |
| Main Portal Vein | Formed by the confluence of the Splenic vein & SMV - Within hepatoduodenal ligament - Bifurcates at the portal hepatis - Anterior to IVC |
| Right portal Vein | Larger, more posterior & caudal than the LPV - branches into A & P divisions |
| Left Portal Vein | Smaller, more anterior & superior than RPV - Abruptly turns anteriorly - Recumbent of H shape |
| Portal Veins | - Enter porta hepatis and decrease in caliber as they course away - Decrease in caliber as they course thru liver - Intrasegmental & Intralobar - Course horizontally - HIGH amplitude reflections - Normal size = 13mm OR 1.3cm 70, 75, 80% |
| Fissures | A groove 1. Main Lobar |
| Hepatic Artery | Carries oxygenated blood from the aorta to the liver - Anterior to portal vein - Adjacent to common bile duct - supply 25% of total blood volume in liver Gastroduodenal Artery - arises from artery |
| Couinaud's Anatomy | - Describes hepatic lesion localization - Hepatic veins divide liver, longitudinally into 4 sections - 8 total segments of liver |
| Reidel's Lobe | - Congenital - NORMAL VARIANT - More common in women - Tongue like projection of the RLL - Extends into iliac crest |
| Situs Inversus | Liver on left side of body |
| Polysplenia/ Asplenia Complex | Liver may be symmetric to midline |
| True Liver Cysts | Congenital - Result from developmental defects in bile duct formation - Contain epithelia lining |
| Acquired Liver Cysts | Lack epithelial lining - Trauma - Parasite - Inflammatory |
| Cysts | Fluid filled mass with epithelial lining - RLL affected 2x as often - ASYMPTOMATIC |
| Adult Polycystic Disease | Incidence: 1 in 1,000 Affects females > men [4:1] - 50/70 years of age |
| Cysts Sonographic Appearance | - Anechoic - Thin walled - Ovoid - Well defined - Posterior acoustic enhancement |
| Cavernous Hemangioma | Asymptomatic - most common benign lesion - more common in women & RLL - Echogenic - Often solitary |
| Liver Cirrhosis | - Alcoholic liver disease - Inflammation & necrosis - Generally Hypoechoic |
| Fatty Infiltration | Acquired, benign reversible disorder of metabolism AKA Steatosis - Asymptomatic - Accumulation of fatty triglycerides - Typically effecting RL - Hyperechoic Alcohol abuse, Obesity |
| Focal Fatty Infiltration | - Non uniform areas - Increase in echogenicity & attenuation |
| Focal Fatty Sparing | - Hypoechoic texture - In medial segment of the LL OR Posterior segment of the RL, Anterior to the GB |
| Hepatitis | - Viruses - Toxins |
| HIV- AIDS | Most common opportunistic infection |
| Schistomiasis | Bacterial infection - from contaminated waters |
| Acute Hepatitis | - Decrease in echogenicity - Hypoechoic - "Starry Night" |
| Chronic Hepatitis | Cirrhosis |
| Hepatitis A | Fecal-oral, or food contamination |
| Hepatitis B | Sexual contact ~ STD - Mother breastfeeding - Contaminated needles |
| The Liver Synthesizes: | - Albumin - Clotting factors |
| Morrison's Pouch | The Hepatorenal recess AKA Subhepatic recess - Space that separates the liver from the Right Kidney - Hepatorenal interface |