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vits

Biochemistry: Water-soluble Vitamins

QuestionAnswer
Mnemonic for water soluble vitamins' B# The Rich Never Pan Pyrite From Creeks (1,2,3,5,6,9,12)
Beri-Beri is due to which vit deficiency Thiamine (B1-->Ber1 Ber1)
What are dry and wet beri beri dry = neurological manifestations. wet = high output CHF due to vasodilation
Enzyme affected with B1 deficiency that leads to Wernicke Korsakoff? transketolase
What cutaneous manifestation occurs due to B2 (riboflavin) deficiency Cheilosis (fissuring of angles of mouth)
_________------>niacin tryptophan
Niacin deficiency is called __________. It's 3 symptoms are __________,_____________, and ______________. Pellagra. Diarrhea, dementia, dermatitis.
Why do corn eaters get pellagra? Corn has no tryptophan (t/f no niacin production)
Which vitamin helps form CoA (for methyl transfer) Panthothenoic acid (aka B5)
Pyridoxal Phosphate is used for what reactions? transaminations, heme synthesis
INH causes drops in what 2 vitamin levels? Niacin and Pyridoxal Phosphate
Folate is used in what reactions? purine/pyrimidine synthesis (as THF)
Storage form of folate? N-methyl folate
Excess folate ingestion can lead to deficiency in ________ B12, because it is used in folate--->THF
What 2 reactions is B12 involved in Homocystein+methyl-THF------>Methionone+THF MethylmalonylCoA---->SuccinylCoA
R binders come from what region? They bind to B12 in the ________ come from salivary glands, bind to B12 in stomach
2 GI problems that can cause low B12 absorption Crohns, Celiac sprue
Created by: jsad
 

 



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