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urinary
| Question | Answer |
|---|---|
| The kidneys filter blood of wastes and excrete them into a fluid called? | Urine |
| What is the scientific study of the anatomy, physiology, and pathology of the kidneys? | Nephrology |
| The branch of medicine that deals with the male and female urinary systems and the male reproductive system is called? | Urology |
| What do kidneys do? | regulate blood volume and composition; help regulate blood pressure, pH, and glucose levels; produce two hormones (calcitriol and erythropoietin); and excrete wastes in urine. |
| What do ureters do? | transport urine from kidneys to urinary bladder. |
| What does urinary bladder do? | stores urine and expels it into urethra. |
| What does the urethra do? | discharges urine from body. |
| Some wastes excreted in urine result from | metabolic reactions |
| What nitrogenous wastes are waste products because they contain nitrogen? | Urea, ammonia, creatinine, uric acid, and urobilin |
| How do the kidneys adjust blood volume? | By conserving or eliminating water in the urine. |
| The kidneys also help regulate blood pressure by secreting which enzyme? | renin |
| Increased renin causes: | increased blood pressure |
| The kidneys produce which two hormones? | calcitrol and erythropoietin |
| What is it called where the ureter emerges from the kidney along with blood vessels, lymphatic vessels, and nerves? | renal hilum |
| What is a floating kidney, is an inferior displacement or dropping of the kidney called? | Nephroptosis |
| What serves as a barrier against trauma and helps maintain the shape of the kidney? | renal capsule |
| What also protects the kidney from trauma and holds it firmly in place within the abdominal cavity.? | adipose capsule |
| Together, the renal cortex and renal pyramids of the renal medulla constitute the functional portion of the kidney called? | parenchyma |
| What are the 1 million microscopic structures in the kidney? | nephrons |
| Each nephron receives one afferent arteriole, which divides into a tangled, ball-shaped capillary network called? | glomerulus |
| What carries blood out of the glomerulus? | efferent arteriole |
| the glomeruli are considered part of which two systems? | the cardiovascular and the urinary |
| The efferent arterioles divide to form what capillaries? | the peritubular capillaries |
| What supply tubular portions of the nephron in the renal medulla? | vasa recta |
| Blood leaves the kidney through which vein, that exits at the renal hilum and carries venous blood to the inferior vena cava? | renal vein |
| Renal nerves are part of which system? | the sympathetic division of the autonomic nervous system. |
| Nephron consists of which two parts? | renal corpuscle and renal tubule |
| The two components of a renal corpuscle are | glomerulus and glomerular capsule |
| What does convoluted mean? | the tubule is tightly coiled rather than straight. |
| The distal convoluted tubules of several nephrons empty into what? | a single collecting duct |
| What connects the proximal and distal convoluted tubules? | nephron loop |
| What makes up about 80-85% nephrons? | cortical nephrons |
| The glomerular (Bowman’s) capsule consists of which layers? | visceral and parietal layers |
| What helps regulate blood pressure within the kidneys? | juxtaglomerular apparatus (JGA) |
| What cells have receptors for both antidiuretic hormone (ADH) and aldosterone, two hormones that regulate their functions.? | principal cells |
| What cells play a role in the homeostasis of blood pH? | Intercalated cells |
| Any increase in kidney size is due solely to what? | the growth of individual nephrons. |
| nephrons and collecting ducts perform three basic processes such as: | glomerular filtration, tubular reabsorption, and tubular secretion |
| What process removes a substance from the blood? | tubular secretion |
| The fluid that enters the capsular space is called? | glomerular filtrate |
| The fraction of blood plasma in the afferent arterioles of the kidneys that becomes glomerular filtrate is called? | filtration fraction. |
| What sandwichlike assembly permits filtration of water and small solutes but prevents filtration of most plasma proteins and blood cells? | filtration membrane |
| Glomerular endothelial cells are quite leaky because they have what? | large fenestrations |
| What contractile cells help regulate glomerular filtration? | mesangial cells |
| What layer of acellular material between the endothelium and the podocytes, consists of minute collagen fibers and negatively charged glycoproteins.? | basement membrane |
| What extends across each filtration slit and permits the passage of molecules having a diameter smaller than 0.006–0.007? | slit membrane |
| What is the use of pressure to force fluids and solutes through a membrane? | filtration |
| Glomerular filtration depends on what three main pressures? | Glomerular blood hydrostatic pressure (GBHP), Capsular hydrostatic pressure (CHP), Blood colloid osmotic pressure (BCOP), |
| What is the total pressure that promotes filtration? | net filtration pressure NFP |
| The amount of filtrate formed in all renal corpuscles of both kidneys each minute is called? | glomerular filtration rate (GFR) |
| The mechanisms that regulate glomerular filtration rate operate in two main ways: | by adjusting blood flow into and out of the glomerulus and (2) by altering the glomerular capillary surface area available for filtration |
| What three mechanisms control GFR? | renal autoregulation, neural regulation, and hormonal regulation. |
| Renal autoregulation and consists of what two mechanisms? | the myogenic mechanism and tubuloglomerular feedback. |
| What occurs when stretching triggers contraction of smooth muscle cells in the walls of afferent arterioles? | myogenic mechanism |
| Norepinephrine causes vasoconstriction through the activation of what? | a1 receptors |
| α1 receptors are particularly plentiful in the smooth muscle fibers of what arterioles? | afferent arterioles |
| This lowering of renal blood flow has two consequences: | (1) It reduces urine output (2) It permits greater blood flow to other body tissues. |
| What reduces GFR? | Angiotensin II |
| What increases GFR? | atrial natriuretic peptide (ANP) |
| Apical membrane contacts which fluid? | tubular fluid |
| Basolateral membrane contacts which fluid? | interstitual fluid |
| Fluid can leak between the cells in a passive process known as? | paracellular reabsorption |
| What membrane proteins that move two or more substances in the same direction across a membrane? | symporters |
| WHat is it that moves two or more substances in opposite directions across a membrane? | antiporters |
| Water reabsorbed with solutes in tubular fluid is termed ? | obligatory water reabsorption |
| Facultative water reabsorption is regulated by antidiuretic hormone and occurs mainly in the what? | collective ducts |
| When the blood concentration of glucose is above 200 mg/mL, the renal symporters cannot work fast enough to reabsorb all the glucose that enters the glomerular filtrate. As a result, some glucose remains in the urine, a condition called ? | glucosuria |
| The fluid that drains from papillary ducts into the renal pelvis is called? | urine |
| The largest amount of solute and water reabsorption from filtered fluid occurs in the ? | proximal convoluted tubules |
| Most solute reabsorption in the proximal convoluted tubule (PCT) involves ? | Na+ |
| Na+ symporters are located where? | apical membrane. |
| What do PCT cells produce that's needed to keep the antiporters running ? | H+ |
| The nephron loop thus sets the stage for independent regulation of both what? | volume and osmolarity of body fluids. |
| The movement of positively charged K+ into the tubular fluid through the apical membrane channels leaves the interstitial fluid and blood with what charges? | negative |
| Reabsorption of Na+ and Cl− occurs by means of ? | Na+–Cl− symporters |
| The principal cells reabsorb___ and secrete ___ | Na+ and K+ |
| What 5 hormones affect the extent of Na+, Ca2+, and water reabsorption as well as K+ secretion by the renal tubules? | angiotensin II, aldosterone, antidiuretic hormone, atrial natriuretic peptide, and parathyroid hormone. |
| Juxtaglomerular cells secrete which enzyme when blood volume and blood pressure decrease, the walls of the afferent arterioles are stretched less? | renin |
| Angiotensin II affects renal physiology in what three main ways: | It decreases the glomerular filtration, It enhances reabsorption of Na+, It stimulates the adrenal cortex to release aldosterone |
| Within principal cells are tiny vesicles containing many copies of a water channel protein known as : | aquaporin-2 |
| What system involving ADH regulates facultative water reabsorption ? | negeative feedback system |
| When the body is dehydrated, the concentration of ADH in the blood ____ | increases |
| When the body is overhydrated (too much water intake), the concentration of ADH in the blood _______ | decreases |
| ANP also suppresses the secretion of _____ and _____ | aldosterone and ADH. |
| a lower than normal level of Ca2+ in the blood stimulates the parathyroid glands to release_________ | parathyroid hormone (PTH) |
| What controls whether dilute urine or concentrated urine is formed? | ADH |
| The ability of ADH to cause excretion of concentrated urine depends on the presence of an _________ of solutes in the interstitial fluid of the renal medulla. | osmostic gradient |
| What are the three major solutes that contribute to this high osmolarity? | Na+, Cl−, and urea. |
| What is the flow of fluid in opposite directions called? | countercurrent |
| Two types of countercurrent mechanisms exist in the kidneys: | countercurrent multiplication and countercurrent exchange. |
| What are substances that slow renal reabsorption of water and thereby cause diuresis, an elevated urine flow rate, which in turn reduces blood volume? | diuretics |
| What is an analysis of the volume and physical, chemical, and microscopic properties of urine called? | urinalysis |
| What makes the color of urine? | urochrome (pigment produced from breakdown of bile) and urobilin (from breakdown of hemoglobin) |
| Typical solutes normally present in urine include filtered and secreted electrolytes that are not reabsorbed called: | urea, creatinine , uric acid , urobilinogen , and small quantities of other substances, such as fatty acids, pigments, enzymes, and hormones. |
| What test measures the blood nitrogen that is part of the urea resulting from catabolism and deamination of amino acids? | blood urea nitrogen (BUN) test |
| what results from catabolism of creatine phosphate in skeletal muscle? | plasma creatinine |
| What is the volume of blood that is “cleaned” or cleared of a substance per unit of time? | renal plasma clearnace |
| What is the separation of large solutes from smaller ones by diffusion through a selectively permeable membrane? | dialysis |
| When directly filtering the patient’s blood by removing wastes and excess electrolytes and fluid and then returning the cleansed blood to the patient is called? | hemodialysis |
| What dialysis uses the peritoneum of the abdominal cavity as the dialysis membrane to filter the blood? | peritoneal dialysis |
| What transports urine from the renal pelvis of one kidney to the urinary bladder? | ureters |
| What pushes urine toward the urinary bladder, but hydrostatic pressure and gravity also contribute? | peristaltic contractions |
| What layer of areolar connective tissue contains blood vessels, lymphatic vessels, and nerves that serve the muscularis and mucosa? | adventitia |
| The prostatic urethra contains: | the openings of (1) ducts that transport secretions from the prostate and (2) the seminal vesicles and ductus (vas) deferens, |
| What gland empties into the spongy urethra? | bulbourethral glands or Cowper’s glands |
| What is a lack of voluntary control over micturition called? | urinary incontinence |
| What is the most common type of incontinence in young and middle-aged females, and results from weakness of the deep muscles of the pelvic floor? | Stress incontinence |
| What is the most common type of incontinence in older people and is characterized by an abrupt and intense urge to urinate followed by an involuntary loss of urine? | Urge incontinence |
| What incontinence refers to the involuntary leakage of small amounts of urine caused by some type of blockage or weak contractions of the musculature of the urinary bladder? | overflow incontinence |
| What incontinence is caused by urine loss resulting from the inability to get to a toilet facility in time as a result of conditions such as stroke, severe arthritis, or Alzheimer’s disease? | functional incontinence |
| Three pairs of kidneys form within the intermediate mesoderm in succession: | the pronephros, the mesonephros, and the metanephros |
| During development, The first kidney to form and is the most superior of the three and has an associated pronephric duct is called? | the pronephros |
| The second kidney during development that replaces the pronephros is called? | the mesonephros |
| What is the condition called when only one kidney develops (usually the right) due to the absence of a ureteric bud? | unilateral renal agenesis |
| What is it called when the crystals of salts present in urine occasionally precipitate and solidify into insoluble stones ? | renal calculi or kidney stones |
| What is the procedure that uses high-energy shock waves to disintegrate kidney stones and offers an alternative to surgical removal? | Shock-wave lithotripsy |
| What is an inflammation of the kidney that involves the glomeruli? | Glomerulonephritis |
| What is a decrease or cessation of glomerular filtration called? | Renal failure |
| What is the procedure for direct examination of the mucosa of the urethra and urinary bladder and prostate in males called? | cystoscopy |