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Hema 2 tests

QuestionAnswer
NV of clotting time Capillary blood: slide and drop- 2 to 4 mins Whole blood: Lee and White- 5 to 15 mins
NV for PT 10-12 seconds
NV for Stypven time 6-10 seconds
NV for APTT 20-45 seconds
NV for TcT 10-14 seconds
NV for Reptilase test 10-15 seconds
Screening test for factor 13 def Duckert’s test or 5 M Urea solubility test
BP cuff of Ivy method 40mmHg
Begin time for clot formation in PT and APPT, when After addition of calcium chloride
Specimen used in PT and APTT PPP which is centrifuged from Citrated blood
Results of PT is reported as INR
PT rgts is assessed by: ISI/ International Sensitivity Index
INR of 2.0-3.0 Pulmonary embolism, DVT, transient ischemic attack
INR of 2.5 to 3.5 Mechanical or prosthetic heart valves
INR of 2.0 to 4.5 Recurrent DVT, pulmonary embolism, MYOCARDIAL INFARCTION, arterial disease
Test that uses activators added to its rgt APTT
Test for factor 1/fibrinogen deficiency Thrombin time or TcT & Reptilase test
Test for common pathway deficiency Stypven time or Russel Viper Venom Time
Standard ISI with best sensitivity Equal to 1
Has ISI equal to 1.0 Manchester’s reagent
APTT reagent Phospholipids, CaCl and activator
PT reagent Tissue thromboplastin and CaCl
Activators used in APTT rgt Silica, Ellagic acid, Celite, Kaolin (SECK)
Factor 1 def test that is unaffected by Heparin Reptilase test
Factor 1 def test that is prolonged with Heparin Thrombin time or ThromboClotting Time
Test for screening Fibrinolytic activity Euglobin lysis time
Euglobin is protein made up of Plasmin, Plasminogen, Plasminogen activator, Fibrinogen
Normal fibrinolytic activity of Euglobin lysis >2 hrs So there is normal finrinolysis
Result of increased fibrinolysis in Euglobin lysis time <2 hours, lysed faster. Increased fibrinolysis = Bleeding
Reptilase source Enzyme found in venom of Bothrops athrox snake
Stypven source From the venom of Vipera Ruselli
Reptilase rgt Atroxin
Clotting time test that is not preferred cause it causes MT injuries Capillary tube/Dale and Laidlaw’s
Yes or No. Is a normal clot soluble to urea within 24 hrs? No
Screening test for Factor 13 deficiency Duckerts Test or 5 M urea solubility test
Test that bypasses coagulation by directly activating Factor X Stypven Time or Russel Viper Venom Time
Test for increased fibrinysis Whole Blood Clot Lysis Time
Detects the presence of fibrin monomers in the plasma Protamine Sulfate Test and Ethanol Gelation Test
More sensitive test that detects the presence of fibrin monomers in the plasma Protamine Sulfate test
More specific test that detects the presence of fibrin monomers in the plasma Ethanol Gelation Test
Created by: Rikkalodeon
 

 



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