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AP Bio A-5-7

Unit five lesson seven

QuestionAnswer
anchorage dependence The requirement that a cell must be attached to a substratum in order to initiate cell division.
benign tumor A mass of abnormal cells with specific genetic and cellular changes such that the cells are not capable of surviving at a new site and generally remain at the site of the tumor’s origin.
cell cycle control system An ordered sequence of events in the life of a cell, from its origin in the division of a parent cell until its own division into two. The eukaryotic cell cycle is composed of interphase (including G1, S, and G2 phases) and M phase (including mitosis and
checkpoint A control point in the cell cycle where stop and go-ahead signals can regulate the cycle.
cyclin A cellular protein that occurs in a cyclically fluctuating concentration and that plays an important role in regulating the cell cycle.
cyclin-dependent kinases A protein kinase that is active only when attached to a particular cyclin.
density-dependent inhibition The phenomenon observed in normal animal cells that causes them to stop dividing when they come into contact with one another.
G0 phase A nondividing state occupied by cells that have left the cell cycle, sometimes reversibly.
growth factor (1) A protein that must be present in the extracellular environment (culture medium or animal body) for the growth and normal development of certain types of cells. (2) A local regulator that acts on nearby cells to stimulate cell proliferation and differ
malignant tumor A cancerous tumor containing cells that have significant genetic and cellular changes and are capable of invading and surviving in new sites. Malignant tumors can impair the functions of one or more organs.
metastasis The spread of cancer cells to locations distant from their original site.
MPF Maturation-promoting factor (or M-phase-promoting factor); a protein complex required for a cell to progress from late interphase to mitosis. The active form consists of cyclin and a protein kinase.
transformation (1) The process by which a cell in culture acquires the ability to divide indefinitely, similar to the division of cancer cells. (2) A change in genotype and phenotype due to the assimilation of external DNA by a cell. When the external DNA is from a memb
Created by: Jason Stanwood
 

 



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