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Cellular Regulation
| Question | Answer |
|---|---|
| What is Cellular Regulation? | Refers to all functions carried out with a cell to maintain homeostasis, includes responses to extracellular signals. |
| Benign? | Non-cancerous, doesn't go anywhere. |
| Malignant/Metastasis? | Cancerous, travels through blood system, become vascular. |
| Mitosis? | Two identical daughter cells |
| Meiosis? | Gametes/sex cells. |
| Consequences of Malignant Neoplasia? | Fear, stress, anxiety, fatigue, weight loss, pain, organ failure, death, changes in family dynamics, financial changes, and changes in self-image and interpersonal relationships. |
| Risk factors of Malignant Neoplasia? | Smoking/tobacco, poor nutrition, excess weight, sedentary lifestyle, genetics, infectious agents, and exposure to environmental carcinogens such as; sunlight, pollutants in the air, soil, water, or food. Medical treatments, or radiation. |
| What are examination findings commonly associated with Neoplasia? | Visible lesions, physical asymmetry, palpable masses, presence of blood in stool or on pelvic examination. |
| What are some infectious agents? | Viruses, some bacteria, H. pylori, HPV, Hep B and C. |
| What are some common diagnostic tests for Neoplasia? | X-rays, MRI, CT, ultrasound, Direct visualization, Lab tests, Pathology. |
| What are some primary preventions for Neoplasia? | Healthy diet, regular physical activity, smoking cessation, avoidance of excessive exposure to sunlight, and prophylactic surgery. |
| What does T mean on a TNM classification? | T= tissues. |
| What does N mean on a TNM classification? | N= lymphnodes |
| What does M mean on a TNM classification? | M=Metastasize. |
| What screening can be done for neoplasia? | Mammogram, prostate-specific antigen, colonoscopy, guaiac test for occult blood, |
| When do you test every 5 years? 3 years? | 5 years= no history 3 years= genetic history |
| What are a few treatment goals for someone with Neoplasia? | Curative, control of the disease, and palliative. |
| Why is surgery an intervention for neoplasia? | Diagnoses, staging, debulking (reducing size), and can be curative if removed before it metastasizes to other tissues. |
| Why debulk a neoplasia? | To shrink down to a more manageable size for chemotherapy. |
| What is chemotherapy? | Pharmacological agents used to prevent cancer cells from multiplying, invading, or metastasizing. |
| What provides systemic treatment to someone with Neoplasia? | Chemotherapy. |
| Radiation side effects? | Burns, hair loss, GI issues, infertility, or affects what areas associated with exposure, fatigue. |
| What is Radiation therapy? | Energy used to damage and kill cancer cells. |
| What is used to specifically target a tissue area for treatment of Neoplasia? | Radiation therapy. |
| What is targeted therapy? | Use of molecular and genetic biology linked to cell functioning. |
| What is biologic therapy? | Use of biological agents to activate the immune system as cancer treatment such as; vaccines, gene therapy, angiogenesis, nonspecific immunomodulating agents. |
| Hormonal therapy? | Used to treat hormonal responsive cancers, breast, prostate, uterine. |
| What is bone marrow and stem cell transplantation? | Replaces diseased or destroyed cells from the bone marrow with normal healthy cells. |