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Resp. Pharmacology I

Pharmacology Cards

QuestionAnswer
Albuterol -Proventil(HFA) Ventolin ProAir Accuneb -Sympathomimetic short acting bronchodilator relaxes muscles/^ airflow SNV:0.5%-0.5ml UNIT DOSE:2.5mg tid,qid MDI:90mcg/puff, 2puffs tid TAB:2,4,8mg bid,tid,qid SYRUP:2MG/ML 1-2 tsp tid,qud -onst15 Pk30 Dur 5-8
Arformoterol -Brovana -Sympathomimetic, long acting, causes bronchodilator -15mch/2ml BID via HHN -onset 15 min Peak 1Hr Dur 12 Hr
Intal -Cromolyn Sodium -Corticosteroid,mast cell stabilizer -mast cell inhibitor,mediates inflammation -2mg/puff >5yr 2pf QID (SVN 20mg/2ml QID for SVN) -onset 15-30 Peak 90-120 Dur 4-6 hr
Formoterol -Foradil -sympathomimetic, B2 selective agonist, long acting bronchodilator -DPI 12mch/puff bid -onset 15 minutes Peak 30-60 Dur 12 H
Ipatropium & Albuterol Combination -Combivent, Duoneb -Parasympatholytic, Sympathomimetic -Bronchodilator, blocks bronchoconstriction --MDI 18(I)/90(A)mcg/puff, 2 puffs qid -onset 15 minutes Peak 1-2 hr Dur 4-6 Hr
Levalbuteral -Xopenex, Xopenex HFA -Sympathomimetic, short acting adrenergic bronchodilator, R Isomer of albuteral -SVN: 0.32/3ml tid or 1.25 mg/3ml tid or 1.25mg/0.5ml tid MDI:45mcg/puff, 2 puffs Q4-6 -Onset 15 min Peak 30-60 Dur 5-8 Hr
Salmeterol -Serevent -Sympathomimetic, B2 long act. bronchodilator *sustained protection /bronchoconstriction -DPI: 50mcg/blister bid -onset 20 min Peak 3-5 Hr Dur 12 Hr
Ipatropium Bromide -Atrovent (HFA) -parasympatholytic, Nonselective M1,2,3 w/2releasing earlier -SVN: 0.02% or 0.2mg/ml) 500mcg tid, qid MDI: 18mcg/pf, 1 pf qid (HFA MDI 17mch/pf, 2 fls qid) -onset MDI 15mn(SNV 1-5mn) Peak 1-2hr Dur 4-8hr
Tiotropium Bromide -Spiriva -parasympatholytic, anticholinergic prevents bronchospasm -bronchitis, emphysema, COPD -DPI: 18 mcg/pf, 1pf daily -onset 30 min Peak 3Hr Dur 24 hr (longest on market)
Fluticasone -Flovent Discus -Corticosteroid -MDI 44,110,220 mcg/pf >12yr 88-880 mcg bid DPI: 50,100,250 mcg bid 100-1000 bid (<12 yr 880 DPI/50 discus) -onset 24 peak 1-2 wks dur 24 hrs
Triamcinolone -Azmacort (CFC) -Corticosteroid -100 mcg/pf, Adult 2pf bid, children 2 pf bid do not exceed 16 daily -onset rapid peak 1.5-2hr Dur 12 hr
Fluticasone with Salmeterol Xinafoate -Advair, Advair HFA -Corticosteroid/B2 agonist, long term maintenance of asthma > 4yrs, maintenance COPD & chronic bronchitis -DPI:100,250,500mcg +50 salmeterol/Pf -onset 30-60 min Pk 3 hrs Dur 12 hrs
Acetylcysteine -Mucomyst -mucolytic breaks down inspissated mucus -3-5ml of 20% sol (or 6-10 ml 10% sol) tid qid -onset 1 min peak 5-10 min dur 2-3 hrs
Dornase Alfa -Pulmozyme -mucolytic, breaks down mucus, adjunct in CF -2.5 mg qid bid via nebulizer (Ped>5yr same) -onset 15min peak 3-8 days dur once daily
Epinephrine -Adrenalin, Adrenalin CL -Sympathomimetic bronchodilator, vasopressor -SVN 1%/0.25-0.5mL (2.5-5.0 mg) qid SVN- 0.25-0.5 ml of 1% strength qid or as ordered MDI- 0.22mg/pf as ordered -onset 3-5min peak 5-20min Dur 1-3hr
Formoterol Fumarate Dihydrate -Performist -sympathomimetic Long acting bronchodilator -Beta2 adrenergic agonist -SVN/Neb: one 20 mcg/2ml fil /12hr
Pirbuterol -Maxair Autohaler -Sympathomimetic -MDI 200 mcg/pf 2 pfq4-4 hours -breath actuated -onset 5min peak 20 min Dur 5 hr
Racemic Epinephrine -microNefrin, Asthma Nefrin -Sympathomimetic ultra short acting adrenercig bronchodilator -Epiglotitis, croup, bronchiolitis -SVN 2.25% sol, 0.25-0.5ml qid (5.63-11.25mg) -Onset 3-5min Peak 5-20min Dur 1-3hr
Terbutaline Sulfate -Terbutaline, Brethine -Sympathomimetic bronchodilator -Adult PO 2.5-5mg tid max 15mg/24hr IND 0.25 mg SQ lateral deltoid repeat 15-30min if necessary max 1.5mg/4hr. -Onset 30 min Peak 2-3 hr Dur 4-8hr
Created by: HeatherPIMA
 

 



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