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MRCS

QuestionAnswer
What is the floor of the inguinal canal? Inguinal ligament
Which rotator cuff muscle inserts onto the lesser tubercle? Subscapularis, the rest insert on the lesser tubercle
Where does the long head of triceps insert? Infraglenoid tubercle of the scapula
Which zones are affected in a)prostrate cancer b)BPH? a)peripheral zone, b)transitional zone
Which muscles are innervated by the obturator nerve? Gracillis, adductor brevis, adductor longus, obturator externus, part of adductor magnus
What is the inferior border of the epiploic foramen? First part of duodenum
Which nerve supplies pectineus? Femoral nerve
Where would uterine tumours spread to? Internal iliac nodes
Which nerve supplies cricothyroid? External laryngeal nerve
What measures FEV1? Spirometry
Which sterile technique kills all organisms including TB, viruses and heat resistant spores? Autoclave
Which sterilisation technique would be used to clean sutures and single use items? Ethylene oxide
Which method would be used for cleaning large amounts of items such as syringes or catheters? Gamma radiation
What method is used to clean endoscopes? 2% glutaraldehyde
What sort of bilirubin builds up in Gilbert's Syndrome? Unconjugated
What factors increase bone resorption? Glutocorticoids, androgens, TSHm prostaglandins, PTH
Which muscle abducts the true vocal cords? Posterior cricoarytenoids
Where do most branchical cysts originate from? 2nd branchical cleft- 75%
What is a cancer marker for breast cancer? Ca 15-3
Which chemo drug works by causing non classical alkylation causing cross linking of DNA strands Cisplatin C, Carboplatin
Which chemo drugs are antimetabolites and interfere with purine/pyrimidine synthesis and interfere with DNA synthesis? Methotrexate, 5FU, Gemcitabine
Which chemo drug is an anthracycline and intercalates DNA strands Doxorubicin
Whcih chemo drug acts by inhibiting mitosis and preventing spindle formation? Vincristine
Which chemo drug inhibits mitosis through stabilisation of microtubules? Docetaxel, Paditaxel
Which chemo drug inhibits topoisemerase I Irintecan
Which facial fracture features: epistaxis, crepitus, severs tooth part of maxilla from upper maxilla Le Fort I
Which facial fracture affects the middle part of the face? Le Fort II
Which facial fracture extends into the anterior fossa via the superior orbital margins? Le Fort III
Flexes the elbow C5
Extends the wrist C6
Extends the elbow C7
Flexes the fingers C8
Flexes the hip L2
Extends the knee L3
Dorsifelxes the foot L4
Wiggles the toes L5
Which fracture causes blow out of C1-usually caused by axial loading Jefferson #
Which # is of the proximal ulna with dislocation of the radial head. Usually caused by fall on forced pronation or forearm, or direct blow to back of the upper forearm? Monteggia
Which # is caused by a fall on the hand causing # to the radial shaft and dislocation of the distal ulna Galeazzi
Where do gluteus medius and minimus insert? Lateral side of greater trochanter
Where does the psoas muscle insert? Lesser trochanter
Where do the external rotators of the hip attach? Lateral side of the greater trochanter
Where does gluteus maximus insert? Gluteral tuberosity of the femus
How much cardiac output does the skin receive? 9%
What is the commonest benign tumour? Leiomyoma
Which chromosome is bladder cancer associated with? 9
Damage to which nerve would cause drooling of saliva and drooping of corner of mouth? Marginal mandibular branch of facial nerve
Where do the inferior parathyroid glands develop from? 3rd pharyngeal pouch, superior develop from 4th
Injury to the radial nerve at the axilla, would cause... Loss of elbow extension, loss of wrist extension and loss of finger extension
Injury to the radial nerve at the spiral groove would cause.... only loss of wrist and finger extension. Elbow extension would be preserved
Which artery supplies the levator scapulae, rhomboids, and trapezius? Dorsal scapular
Where are the areas of oesophageal constriction? Cricopharyngeal sphincter 15cm, aortic arch 22cm, left main bronchus 27cm
A patient presents with bleeding from the posterior gastric wall, which vessel is involed? Splenic artery
What causes Kerr's sign on the left? Splenic rupture
What crosses the ureter at the pevicuteric junction? Vas deferens or broad ligament of the uterus
What is the most common type of hypospadiasis? Glandular hypospadiasis (1 in 300)
What measures the extrinsic pathway? Prothrombin Time, usually 1-13 seconds, prolonged by Warfarin, Liver disease and DIC
What measures the intrinsic pathway? APTT, usually 35 seconds, prolonged by haemophillia A&B, Heparin and DIC
When should tamoxifen be stopped pre op? 4 weeks
Which factors does heparin inhibit? IIa, IXa, Xa, XIIa
Which muscle relaxant is used for rapid tracheal intubation? Suxamethonium
Which vitamin is involved in collagen cross linking? B6
Which vitamin is involved in hydroxylation of proline and lysine? C
What is the risk of getting the following post needlestick injury? Hep B, Hep C, HIV 30%, 3%, 0.3%
Which dressing is good for exudating wounds? Aquacel
Which scan is used for? Thyroid Parathyorid HPB Myocardial perfusion Iodine 12B Technetium sestamic HIDA Thallium 20
What is the most abundant cell? Neutrophil
What is the largest leukocyte? Monocyte
What is the normal CVP? 8-12 mmHg
Where is a central chemoreceptor and what does it do? Detects changes in pH/CO2 crossing the BBB
What do peripheral chemoreceptors detect? Changes in PaO2, carotid body via CNIX, aoritc arch via vagus
Which fibres transmit acute sharp pain? A, C fibres transmit slow chronic pain
Where do A fibres terminate? Lamina 1 and 5 in the dorsal horn
Where do C fibres terminate? Lamina 2&3 in the substantia gelatinosa
What does afferent vasoconstriction cause? Reduced GFR and glomerular plasma flow
What does efferent arteriolar vasoconstriction cause? Increased GFR
What are the differences between endotoxin and exotoxin? Endotoxin remains within cell wall of bacteria, exotoxins are actively secreted by bacterium
Which inotrope activates beta recptors and increases intracellular camp? Adrenaline
Which inotrope affects predominantly B1 and HR and increases force of contraction? Dobutamine
Which inotrope increases SVR? Noradrenaline
Which trope increases cardiac relaxation? Lusitropes
Which deficiency is linked with bacterial infections? C3
Which complement deficiency is linked with recurrent neisseria infections? C5-8
What are examples of exotoxins? Gram +ve bacteria like clostridium
What are examples of enterotxins? Staph A, E Coli
Which herpes virus is linked with a)EBV, b)CMV? a:4, b:5
Where would giardia lamblia accumulate? Duodenum
Where does cryptosporidium lodge? Brush border of villi
Which antigens are on all platelets and nucleated cells? Class I Class II are on all dendritic cells, macrophages, b lymphocytes and activated T cells
Which interlukin stimulates proliferation of B and T cells? 2
Which interleukin promotes differentiation of CD4 and B cells 4
Which interleukin stimulates activation of eosinophils 5
Which disease as antibodies against parietal cells? Atrophic gastritis
What is anti-centromere associated with? CREST syndrome
What is Anti Scl 70 associated with? Scleroderma
Where are indirect hernias in relation to the inferior epigastric vessels? Lateral
What are the boundaries of calot's triangle? Superior-inferior edge of the liver, lateral- cystic duct, medial- common hepatic duct
Where does the aortic arch end T4
Where does SCC arise from? Stratum spinosum and epidermal appendage. Needs a 4mm margin to be clear and 6mm if high risk
What are the 4 steps of skin graft healing? Adherence, plasmatic imbition, revascularisation, maturation
What forms the lateral wall of the femoral triangle? Sartorius
What symptoms is campylorbacter jejuni associated with? Severe abdominal pain and diarrhoea
Where is most dietary iron absorbed? Duodenum
What is mcKeown's procedure? Total oesophagectomy
What runs medially to the pars flaccida? Chorda tympani
Which study would use relative risk? Cohort study
Which study would use odd's ratio? Case-control
Which muscle relaxant can cause malignant hyperthermia? Suxamthonium
What is the most posterior structure at the hilum of the right kidney? Ureter
What are psammonal bodies? Clusters of microcalcification mainly seen in papillary carcinoma
Which bacteria stain purple? Gram +ve
Which bacteria have LPS in outer membrane? Gram -ve
Which fibres lead to contraction at the apex before the base? Purkinje
What does the cystic artery arise from? right hepatic
Which cells produce VIP? Pancreatic D
What are the contents of the cavernous sinus? ICA, CN VI, blood
Which nerve provides parasympathetic innervation to the parotid salivery gland? Glossopharyngeal via auriculotemporal
When is fusion of the ilium, ischium and pubis at the acetabulum complete? 23 years
What can the kidneys generate bicarbonate from? Glutamine
What is the volume capactiy of the gallbladder? 50ml
Where is 70% sodium reabsorbed? PCT, 20% ascending loop of henle, 10% DCT
What is the left gastroepiploic artery a branch of? Splenic
What is the most radiodense stone? Calcium phosphate
What is the commonest cause of filarisis? W. Bancrofti
Which cranial nerves carry parasympathetic finres? X, IX, VII, III (1973)
What are the main flaps used in BKA? Skew flaps or Burgess long posterior flap
Which type of amputation preserves the patella?? Gritti stokes
What is Hadfield's procedure? Total duct excision
What is Mondor's disease? Superficial thrombophlebitis of s/c veins of the chest
Which antibodies are elevated in Grave's disease? Thyroid receptor
Which antibodies are elevated in hypothyroidism? Thyroid peroxidase
Which thyroid tumour is TSH dependent? Papillary and follicular
Which ligament prevents abduction above the knee? Medial collateral
Which technique analyses DNA? Southern Blotting
Which technique uses mRNA as the target nucleic acid? Northern Blotting
Which technique analyses proteins seprated by electrophoresis? Western Blotting
Which heart sound coincides with QRS complex? 1st
When would you see high numbers of Auer Rods? AML
Which cells in the adrenal medulla release adrenaline? Chromaffin
Which nerve wraps around Wharton's Duct? Lingual
What promotes gastrin release? Distended stomach
Whait is released by S cells in the upper small intestine and reduces gastric acid? Secretin
What inhibits gastric acid and pepsinogin? VIP
What stimulates bile and pancreatic juice production? Secretin
What is the commonest cause of infrarenal outflow obstruction? Posterior urethral valves
Which suture lasts up to 3 months? PDS
How is biliary atresia managed? Roux en Y portojejunostomy aka Kasai Procedure
What lesion causes Erb's palsy? c5, c6
Which virus is linked with anal cancer? HPV 16
Which stoma is formed after low anterior resection? Loop ileostomy
Which stoma is formed after large bowel obstruction? Loop colostomy
Which stoma is formed after subtotal colectomy? End ileostomy
How is blood stained nipple discharge managed? Microdochectomy
What is the substrate for renin? Angiotensinogen
What skin graft would be used for a full thickness burn? Split thickness graft
When would trans metartarsal amputation be indicated? Diabetic gangrene
Where does the axillary artery become the brachial? Lower border of teres minor
Which artery stenosis causes intermittent claudication? Superficial femoral
Aortoiliac disease is treated with which bypass?- presents with buttock and hip pain Aortobifemoral
Which bypass would be used in isolated external iliac disease? Ileofemoral bypass
If only one iliac artery is blocked and the pt is unfit for abdominal surgery which graft is used? Fem-fem crossover graft, if both arteries are occluded then axilofemoral graft
What causes horseshoe kidney? The kidneys fuse at the infeior pole and fail to ascend
Which embryological structure becomes the functioning kidney? Metanephros
Where do the bladder and urethra descend from? urogential sinus
Which cells produce mullerian inhibitory substance? Sertoli Cells, this causes regression of the parameseonephric ducts
What is the most common malignant brain tumour in children? Medulloblastoma
Which hernia occurs with the appendix within the inguinal hernia sac? Amyand's
Where do the Vas Deferens develop fron? Mesonephric ducts
What is a remnant of allantois? Urachus
Where does the male urethra develop from? Cloaca
Where is the internal iliac artery in relation to the ureter and vein? Ureter is anterior, the vein lies posterio
Where does the body of the uterus drain? Iliac lymph nodes
Where is the isthmus of the thyrpid? 2nd-4th tracheal rings
Where is oesophageal opening in the diaphragm? t10 in the right crus
Where is the vena cava opening in the oesophagus? Central tendon T8
What is the function of the femoral canal? Allows expansion of the femoral vein
What does an orbital floor fracture cause? Enophthalamos and diplopia
What does the Hawkin's test test? Subacromial impingement
What does Jobe's test test? Suprapsintaus injury
What is the equation for cerebral perfusion pressure? CPP=MAP-ICP
What happens to SVR in septic shock? Reduces it due to increased bacterial exotoxins causing peripheral vasodilatation
What is the arterial supply to the prostate? Inferior vesical artery
Where does the uterine artery run? Base of broad ligament, it is branch of the internal iliac
Where are the roots of the brachial plexus? Between scalene anterior and medius
What is a typicial chemo regime in breast ca? Cyclophosphamide, methotrexate, 5FU
What is the gold standard for detecting renal calculi? CT urogram
What is the risk of repeat MI if operation is 3-6 months after a MI? 6%
Which test is used for autoclaving efficacy? Bowie-Dick
How many sections are in the WHO checklist? 3
Where does the SVC enter the right atrium? Behind right C3
How much tibia is required to fit a prosthesis? At least 8 cm
What is the protien count of CSF compared to plasma? 0.5%
When does the diaphragm form? 9-2 weeks
Which nerve is at risk during submandibular duct ligation? Lingual
What level is the ureteropelvic junction? L2
Herniation of which disc affects dorsiflexion? L4/5
Herniation of which disc affects plantarflexion and decreased ankle jerk? Lf/21
Where do oesophageal veins drain? Azygous veins
Which ligament is in direct contact with the vertebral foramen? Ligamentum flavum
Where does the dural sac end? S2
What is the action of latissimus dorsi? Adduction and medical rotation of the humerus
What level in adults is lumbar puncture performed at? L4/5
Where do the external genitalia drain? Superficial inguinal nodes
Which arteries are within the spermatic cord? Cremasteric, tesitular, artery to vas
What forms the trauma triad of death? Hypothermia, coagulopathy, metabolic acidosis
Where is the larynx in children, adults C3-4, C4-5
Which nerves are parasympathetic? CNIII, CN VII, CN IX, CN X, S2-s4
Which receptor is noradrenaline more potent than isoprenaline? alpha, but vice versa at beta
What is sensitivity? Measure of true positives
What is specificity? Measure of true negatives
Which neurotransmitter is usually released at post ganglionic sympathetic endings? Noradrenaline, at eccrine sweat glands it is ACh
Which hormone does bronchial cancer produce? Calcitonin
Which hormones are produced by testicular teratomas? BHCg, thyroxine, AFP
Which nerve is anterior to the lung root? Phrenic
Which necrosis occurs post MI? Coagulative
What level does the azygous drain into the SVC? T4
Where does the thoracic duct drain? Confluence Left jugular and subclavian veins
What toxin does E.coli 0157 produce? Enterotoxin
What signifies active or chronic hep b? S antigen
Which antigen signifies active replication and high infectivity of hep B? e antigen
What is the proper name of chinese liver fluke? Clonorchic Sinesis
Which bacteria produce hyalurinidase? S.Aureus, S. Pyogenes, C. Perfringenes
Which stage of the cell cycle are cells not actively replicating? G1
Which toxin in tobacco is associated with bronchogenic ca? Napthylamine
What is compliance? Change in volume for a given change in pressure
How quickly does the exudative phase develop in ARDS? 30 minutes, characterised by interstitial oedema, alveolar haemorrhage, the oedema leads to alveolar collapse
What is the main site of absroption of amino acids and lipids? Ileum
What are the features of the jejunum compared to ileum? Thicker wall, more vasculare, more circular folds, fewer lymph aggregates
Where does the cystic artery arise from? Right hepatic artery
Which amino acids are a major stimulant for gastric secretion? Phenylalanie and tyrosine
What does the portal vein develop from? Vitteline venous plexus
Where are 90% of bile salts absorbed? terminal ileum
What is the lateral coticospinal column responsible for? Motor function
What is the posterior spinal column responsible for? Position, vibration, and deep pressure sensation
What are the features of spinal shock? Paralysis, hypotonia, areflexia
Which ligament is affected in Jefferson's fracture? Transverse ligament rupture
Which herniation causes Cushing's Triad? Cerebellar tonsil
Which artery supplies the sciatic nerve? Inferior gluteal
What does the Y waveform on JVP show? Ventricular filling
What is at risk in axillar node clearance? Thoracodorsal trunk
Which organisms are lactose fermenting? E.Coli, Klebsiella
What causes amoebiasis? Entmceba histolytica
Which nerve supplies sensation to the inferior part of the ear? C3- greater auricular nerve
What are the strap muscles? Sternohyoid, thyrohyoid, styrohyoid, omohyoid
Which dermatome is the shoulder tip? C4
What are the nerve roots of the musculocutaneous nerve and what does it supply? C5-C7, corachobrachialis, bicpeps brachia, brachialis
Which nerve root is damaged in Klumpke's palsy? T1
Where is the radial nerve in relation to the axillary artery? Posterior to it
What are iodine dressings used for? Infection/ exudative wounds
What is the risk of CBD injury in cholecystectomy? 0.5%
What are the features of neurogenic shock? Bradycardia, warm peripheries, no response to fluids
Where does anterior tongue cancer spread? submental, submandibular, deep cervical nodes
Where does posterior tongue cancer spread? bilaterally to lymph nodes
Which hormone is increased in the menopause? FSH
What is the medial border of the femoral canal? Adductor longus
What is the lateral border of the femoral canal? Sartorius
What is the superior border of the femoral canal? Inguinal ligament
Which bone cell does PTH directly act on? Osteoblasts
Where are Brunner's glands located? Submucosa of the duodenum
What are the roots of the ankle reflex? S1, S2
What does LMWH inhibit? Factor Xa
What is the management of recurrent duct ectasia? Total duct excision
What is normal cerebral blood flow? 55ml/minute for every 100 gram of brain tissue. Ischaemia occurs when it falls below 20ml/min
What is Sistrunk's procedure? Excision of thyroglossal cyst
Which nerve injury causes difficulty in vocal pitch? Superior laryngeal
Diphonia and dysphagia is caused by injury to which nerve? Unilateral inferior laryngeal nerve
What can be used to treat GI parasitic worms? Mebendazole
Which enzyme activates trypsinogen? Enterokinase
What is the most commonly displaced carpal bone? Lunate
Which receptor does dobutamine bind? B1
Which stain is used in amyloidosis? Congo-Red-stains apple green
What would deficiency in production of J Chain produce? Decreased serum IgA and IgM
Which virus causes myocarditis? Coxsackie B
Which nerve is secreto-motor to the lacrimal gland? Facial
Which organism produces urease which can form staghorn calculi? Proteus mirabilis
What is contained in the lienorenal ligamanet? Splenic artey and tail of pancreas
Which virus can complicate blood transfusion? CMV
Which chromosomes are involved in Hirschspring disease? 10 and 13
What is the function of quadratus lumborum? Pulls the ribcage inferiorly and lateral flexion
What structures are posterior to the medial malleolus? Tibialis posterior Flexor digitorum longus Posterior Tibial artery Tibial nerve Flexor hallicus longus
What is Barton's fracture? Distal radius fracture with radiocarpal dislocation
What aDDucts the vocal cord? Lateral cricoarytenoid
Which vessel may be encountered during tracheostomy? Anterior jugular vein
What forms the posterior wall of the femoral canal? Pectineal
Where is the vomiting centre located? Medulla oblongata
How is anatomical dead space measured? Fowler's Method
Which structure is most posterior at the lung root? Vagus nerve
Which cells indicate follicular cancer? Hurtle Cell tumours
What causes Lynch syndrome? Microsatellite instability of DNA repair genes
What is the neurotransmitter for Purkinje neurons? GABA
What does ondansetron block? CTZ in postrema
Which tendon lies closest to hamate in the carpal tunnel FDP
Which finger does not have palmar interosseous? Middle finger
Which muscle is penetrated by the parotid duct? Buccinator
Which sinus empties into the IIJV? Sigmoid
What is the terminal branch of the inferior alveolar nerve? Mental
How do you treat insulinoma? Enucleation of the lesion
What is a Hangman's fracture? Traumatic spondylothesis of C2 on C3
What is medial epicondylitis aka? Golfer's elbow
Which part of the urethra is the narrowest? Membranous
How should you investigate a neonate with bilious vomiting? Upper GI contrast study
How would a ureteric stone <2cm be managed? Lithotripsy
What innervates the long head of biceps femoris? Branch of sciatic nerve
What innervates the shorthead of biceps femoris? Common fibular branch of the peroneal nerve
Which drain would be used post mastectomy? REdivac suction drain
Which artery supplies Broca's area? Middle cerebral artery
Where does the prostate gland drain? Internal iliac nodes
What innervates the prostate? Inferior hypogastric plexus
What is the main pancreatic duct aka? Wirsing's duct
What is the accessory pancreatic duct aka? Santorini duct
What nerve supplies sensation to the suprapubic skin? Illiohypogastric
Which tongue papilla grip food? Fuliform
Which tongue pailla tastse sweet/salty food? Fungiform
Which tongue pailla detect sour tastes folate
Which vein arises in the anatomical snuff box? Cephalic vein
Where does the submandibular duct lie? Between mylohyoid and hypoglossus. It opens into the floor of the mouth adjacent to the frenulum
Where does the tongue develop from? 1st and 3rd branchial arch
What does PTH do? Increases calcium from bone and kidney, increases vit d
What does neutrophils produce? Hydrogen peroxide
Which nerve supplies aBDuctor pollicis longus? Posterior interosseous nerve
What nerve supplies aBDuctor pollicis brevis? Median nerve
When does the descending colon become sigmoid? L3,L4
What attaches periosteum to bone? Sharpey's fascia
Where does the vagus nerve leave the medulla? At the olivary nucleus and inferior to the cerebellar peduncle
What are the layers of the scrotum? Skin Dartos External spermic fascia Cremasteric muscle and fascia Internal spermatic fascia Tunica Vaginalis
What is the initial mangement of congenital talipes equinovarus? Ponsetti method- serial casting
What supplies the anterior digastric muscle? Mylohyoid nerve
What supplies the posterior digastric muscle? Facial nerve
What induces satiety? Leptin
What induces hunger? Grehlin
Where does the trigeminal nerve originate? Pons
What is the lateral border of the adductor canal? Vastus medialis
How long can you store FFP? 36 months
What are the contents of the adductor canal? Saphenous nerve, superficial branch of femoral
Which nerve innervates the nail bed of the index finger? Median nerve
Which ligament seprates the IV discs from the spinal cord? Posterior longitudinal ligament
Where does the posterior ethmoidal sinus drain? Superior meatus
Where do the frontal and anterior ethmoidal cells drain? Infundibulum of the middle meatus
Where do the maxillary sinus and middle ehtmoidal cells open? Middle meatus
What are the features of O'Danaghue's unhappy triad? Tear ACL Tear MCL Meniscal tear
What is the most radiosensitive testicular tumour? Seminoma
What is normal portal vein pressure? 5-10mmHg, portal HTN develops at 12mmHg
How much does 1gram nitrogen loss equate to lean muscle loss? 36 gram
What vein does the basillic drain into? Axillary
Which cells are affected by poliomyelitis? Anterior horn cells= lower motor neurone palsy
Which anaesthetic is used in brier's block? Prilocaine
Which anaesthetic is used in spinals/epidurals? Bupivacaine
What dermatome signifies inguinal ligament? T12
Which hormone is responsible for ion exchange in the salivary glands? aldosterone
Which structure is deepest in the popliteal fossa? Popliteal artery
Which muscles insert onto the superior medial tibial shaft? Sartorius, gracilis, semitendinous
What nerve can be compressed by anterior dislocation of lunate? Median nerve
Which stain identifies toxoplasmosis gonadii? Giemsa
Which vitamin deficiency can cause bladder calculi? A- causes desquamation which causes nidus formation
Which kidney infection causes alkaline urine? Proteus
Which hormone do small cell lung cancers produce? ACTH
Which oepration is used for ingrown toenails? Zadik's
Which muscles flex the hip? Sartorius Tensa fascia latae Rectus femoris Iliopsaos Pectineus
What is normal pulmonary artery wedge pressure? 18mmHg
What group is strep pyogenes in? Lancefield group A
What can be used to monitor follicular cnacer? Thyroglobulin
What is used to monitor medullary cancer? Calcitonin
Which level is the xiphoid process? T7
Which clotting factor forms a complex with tissue factor? 8
What position is used for nephrectomy? Lateral decubitus position
What is vital capacity? Volume of air that is expelled from max inspiration to max expiration
Which reflex prevents overinflation of the lungs? Hering-Breuer reflex
When does renal autoregulation fail? SBP <80mmHg
What is most common toxin from cat bite? Paseurella multicida
What is most common pathogen in THR infection? Staph epidermidis
What supplies the first web space in the hand? Superficial radial nerve
What innervates pronator quadratus? Anterior interosseous nerve
What forms the medial wall of the axilla? Serratus anterior
What is afterload? MEasure of tension in the left ventricular wall during systole
What is the anterior border of the epiploic foramen? Portal vein
What is transmitted by the anterior spinothalamic tract? Crude touch
What is Jenkin's rule Length of suture if 4 times the length of the wound
How does picolax work? It is magnesium sulphate, stimulates release of CCK which promotes intestinal motility
What are the pro-inflammatory cytokines that also cause pyrexia? TNF-a, IL-1, IL-6, IL-8
Which fascia covers the sacrum and coccyx? Waldeyer's
Which procedure can be used for adult hydrocele? Jaboulay/Lord's
What is the management of pleiomorphic adenoma? Superifical parotidectomy
Which amputation uses skew flaps? BKA
How would you mangafe obstructed infected calculi? Broad spectur abx, percutaneous nephrostomy
What forms the roof of the adductor canal? Sartorius
What forms the posterior wall of the adductor canal? Adductor longus and magnus
What is the resting muscle membrane potential? -90
What is the commonest presentation of ulcerative colitis? Priaprism
Which artery winds around midshaft of the humerus? Brachial artery
Which cells form the primary callous in #healing? Osteoblasts
What condition happens post cardiac surgery? Acute mediastinitis
What is the incidence of cleft lip and palate? 1 in 600 live briths
What is Parotid duct known as? Stenson's duct, opens adjacent to 2nd molar teeth, mainly serous saline fluid
What is likely to have developed if patient becomes suddenly anuric post transplant? Renal artery thrombosis
What forms the roof of the inguinal canal? Conjoint tendon
What forms the posterior wall of the inguinal canal? Transversalis fascia
What forms the anterior wall of the inguinal canal? External oblique aponeurosis
What forms the floor of the inguinal canal? Inguinal ligament
What is first line for varicose veins? Endothermal ablations
What is a congential cause of lymphoderma? Milroy's disease
What are the features of aortoliac obstruction? Claudication in both buttocks, thighs, calves
What are the features of iliac obstruction? Unilateral claudication in thigh, calf and buttocks, bruit over iliac regions, unilateral absence of femoral and distal pulses
What are the features of femoropopliteal obstruction? Unilateral calf claudication, palpable femoral pulse, absent unilateral distal pulse
At McBurnley's point, which structure is encountered first in dissection? External oblique aponeurosis
Where does the cervix drain? Internal iliac nodes
Where is water mainly absorbed? Jejunum
what marks junction between duodenum and pylorus? Vein of Mayo
What is normal inspiratory reserve volume? 3000ml
which foramen connects the 2 lateral ventricles with the 3rd ventricle? Foramen of Munro
What causes ACL damage? Twisting of slightly flexed knee- netball- pop sounds
What causes MCL damage? Blow to lateral aspect of knee
Posterolateral disc protrusion causes/// nerve root pain and sciatica
Where are level I breast nodes? Lateral to pectoralis minor
Where are level II breast nodes? Behind pectoralis minor
Where are level III breast nodes? Medial to pectoralis minor
How does UV light act as antimicrobial? Causes formation of pyrimidine dimers
Which nerve is likely to be injured after deep laceration to the thenar eminence? Recurrent branch of median
Which nerve is tested by Froment's test? Anterior interosseous nerve
What is the most common testicular cancer in maldescended testis? Seminoma
What is the commonest cause of blood stained nipple discharge? Intraductal papilloma
What is the intrabdominal pressure in critically ill patients? 5-7 mmHg
Where is zinc mainly absorbed? duodenum and jejunum
What are the contents of the right atrium? Fossa ovalis, opening of coronary sinus, crista terminalis, musculi pectinati
Which muscles tenses the vocal folds? Cricothyroid
How does HIV establish persistance? Antigenic variation
Which clotting pathway is affected by haemophillia A Intrinsic
Which amino acid produces nitric oxide? Arginine
What syndrome is posterior cricoid tumour associated with? Plummer Vinson
Where is the primary visual cortex located? Brodmann area 17
What is the oldest part of the brain? Limbic system
Which artery supplies ACL? Middle geniculate artery
Which nerve carries fibres for lacrimation? Greater petrosal
Which renal stones are radiolucent? Urate, xanthine
Which immunoglobulin is first secreted in infection? IgM
Which IL stimulates production of eosinophils? IL-5
where is the Meissner's plexus? Submucosa
Which abx inhibit DNA synthesis? Quinolones
Which cells are the main source of IL-12? B cells
What does tranexamic acid inhibit? Plasmin
What does string sign of Kantor represent? Narrowing of the terminal ileum
When is AP resection indicated? Cancer <4cm from anal verge
Which graft has the best patency? Above knee anastomosis using long saphenous vein
where does the upper anus drain? internal iliac nodes, supplied by superior rectal artery and vein
Where does the inferior anus drain? Superficial inguinal nodea
What is Goodsall's rule for posterior fistula? Always have internal opening at 6 oclock- curved tract
Which repair is preferred for herniaS? Tension free Lichenstein rather than sutured shouldice
What is the repair for paraumbilical hernias? Mayo repair
Which hernia passes through linea semiluminaris/ Spigelian
What is factor II aka? Prothrombin
What is HbcAG a marker of? Ineffectivity
What effect do prostaglandins have on renal flow? Increase renal blood flow and GFR?
Where is fat mainly absorbed? Proximal small intestine
Which chromosome is the APC gene found? Chromosome 5
What is the main method intracellular pH is regulated? Cytoplasmic proteins
What are non absorbable sutures? Polyprolene, silk, nylon, pvdf, steel
What is the commonest germ cell testicular cancer? seminoma
What is marantaric endocarditis aka? non bacterial thrombotic endocarditis
What is dartos fascia a continuation of? scarper's fascia
What is gluconeogenesis? Formation of glucose from non carbohydrate sources-glycerol, lactate, amino acids
Which nerve is involved in Frey's syndrome post parotidectomy? Auriculotemporal
What are the features of spermatocele? Fluid filled cyst at the upper pole of the testis
What does specific gravity test? Concentration
What lies in the retrovesical space in men? Seminal vesicles
What are the effects of thyroxine? Increases tissue oxygen consumption Stimulates protein synthesis Decreases plasma cholesterol Causes a net reduction in lipid stores
What is the treatment for thyroid storm? Intravenous hydration Intravenous propranolol Propylthiouracil and sodium iodide
When could a HCW infected with Hep B perform procedures? 1. e-antigen negative 2. Baseline viral load less than 105 geq/ml and 3. Viral load should fall below 103 geq/ml while taking antiviral therapy
What is the minimum amount of Hep B vaccine required? 3 doses
What colour can propofol turn urine? Green
What is the treatment for malignant hyperthermia? Dantrolene
What is the most prominent extracellular ion Sodium
What is the most prominent intracellular ion potassium
What does calcitonin do? Calcitonin acts to oppose PTH, so causing increased renal excretion and reduces bone resorption
What is the most common cause of vasodilatory shock? Sepsis
What is the absolute maximum pressure of a tourniquet? 350mmHg
What are the lowest effective tourniquet pressures in arm and leg? Use the lowest effective pressure 100 mmHg over systolic BP for arm !50 mmHg over systolic BP for leg
What are the main symptoms of fat embolism? Petechiae, hypoxaemia, confusion
What is the mechanism of Basiliximab ? immunosuppression induction agent.
Which drugs are calcineurin inhibitors? cyclosporine and tacrolimus. These agents both inhibit calcineurin, an important enzyme in the T-cell activation pathway.
What are the side effects of calcineurin inhibitors? nephrotoxic. chronic allograft nephropathy and graft loss. narrow therapeutic -blood levels must be monitored. neurotoxicity, htn, hyperlipidaemia and glucose intolerance. New-onset diabetes- tacrolimus Cyclosporine -hirsuitism &gingival hyperplasia.
What are the side effects of antimetabolites? The most important side effect of azathioprine and mycophenolate mofetil is bone marrow suppression, and the full blood count must be monitored.
What are the features of cell mediated acute rejection? Peritubular infiltration with monocytes and foamy macrophages
What are the features of Chronic allograft nephropathy? Interstitial fibrosis with arteriolar smooth muscle hypertroph
What is an Orthotopic graft? Implanted in the position of the native organ/tissue
What is an Heterotopic graft? Implanted in a position different from the native organ/tissue
Which solution is used to preserve the kidneys? Marshall’s solution (Soltran™)
Which solution is used to preserve abdominal organs? University of Wisconsion solution (ViaSpanâ„¢
Non-absorbable skin closure 3-0 polyprolene
What are the stages of wound healing? Haemostasis (Day 1) Inflammation (Days 1-7) Proliferation (Days 3-21) Remodelling (Day 14-12 months)
What is the spring ligament? The spring ligament or plantar calcaneonavicular ligament, is a support for the medial longitudinal arch on which the head of the talus rests. It is a major restraint preventing the head of the talus moving medially and collapsing inferiorly.
Rupture of which tendon causes flat foot deformity? Rupture of tibialis posterior tendon leads to a severe secondary flat foot deformity.
Which clotting factor stabilises fibrin? Factor XIII
What forms the anterolateral border of the adductor canal? Vastus medialis
Which vertebrae are predominantly coronal? thoracic
Where is the internal venous plexus of the spine? Extradural fat
What is the role of FSH in men? Stimulates synthesis of androgen binding protein
Which muscle is crucial to hindfoot position? Tibialis posterior
What is a tributary of IJV? Middle thyroid vein
What percentage of gallstones can be seen on plain xray? 15%
What can increase renal blood flow and GFR? Prostaglandins
What percentage of developing breast cancer do people with BRCA1 have? 50% by age of 50
Where is the fossa navcularis in the penis? Small dilatation in the distal penile urethra
What are features of Men2a? Medullary thyroid cancer, phaecochromocytoma and parathyorif hyperplasia
Who should have BRCA testing? Women <35 with triple negative breast cancer
Which fracture is associated with posterior hip dislocation? acetabulum
What is Liddle syndrome? Rare AD, hypokalaemia and hypertension, unrestrained sodium reabsorption
What is the ophthalmic artery a branch of? Internal carotid artery
What is the best test for acromegaly? Oral glucose tolerance with GH levels
What is the first heart sound? Closing AV valves
How does calcitonin work? Inhibits bone resorption by inhibiting osteoclasts.
What is the action of co-amoxiclav? Inhibits cell wall synthesis
what is the most common cause of epididyitis in children? e.coli
Where is the aortic apperture? Behind the median arcuate ligament. In the mid-line.
What is the course of the thoracic duct? The thoracic duct extends from L2 to the root of the neck & lies immediately posterior to the esophagus & may be injured while mobilizing the esophagus in the neck.
Which muscle is the main extensor of the hip? Gluteus maximus
Where does quadriceps femoris insert? Tibial tuberosity
Which muscles inserts on the base of the 5th metatarsal? Peroneus brevis
What are the 3 components of the femoral sheath? 1. The medial is called the femoral canal. 2. The middle contains the femoral vein. 3. The lateral contains the femoral artery.
What are the components of Hunter's canal? 1. Femoral artery & vein. 2. Saphenous nerve. 3. Nerve to vastus medialis
What does the sphenoid bone contain? The optic foramen, superior orbital fissure, foramen rotundum, ovale & spinosum.
What is the arterial supply of the adrenal glands? 1. Superior supra-renal from inferior phrenic artery. 2. Middle supra-renal from abdominal aorta. 3. Inferior supra-renal from renal artery
Which nerve transmits pain from anal fissure? inferior rectal nerve
Which cell type is increased in patients with hydatid cysts? Eosinophils
What is the most abundant immunoglobulin? IgG
Which complement activates membrane attack complex? C5b
What can pass through the blood brain barrier? 1. Lipid-soluble substances (O2, Co2, ethanol & steroid hormones). 2. Substances having transport systems (sugars & some amino acids). 3. Serotonin (5HT).
What is the management of testicular tumours? orchidectomy via an inguinal approach. This allows high ligation of the testicular vessels and avoids exposure of another lymphatic field to the tumour.
Where are the greatest proportion of musculi pectinati found? right atrium
What is the treatment for intestinal malrotation? Ladd's procedure
hich of the structures separates the subclavian artery and vein? Anterior scalene muscle
A 6 day old child is suspected of having a malrotation and requires urgent abdominal exploration. What is the most appropriate surgical approach? Transverse supra umbilical abdominal incision
A 32 male presents with a swollen RTscrotum which has developed over 3 weeks after being kicked in the groin area. There is a non tense swelling of the right scrotum and the underlying testis cannot be easily palpated. What is the most likely diagnosis? Hydrocele
Which of these nerves passes through the greater and lesser sciatic foramina? Pudendal nerve Internal pudendal artery Nerve to obturator internus
Which lung cancer is more common in non smokers?? adenocarcinoma
How does a patent urachus present? umbilical urinary discharge
At which of the following levels does the inferior thyroid artery enter the thyroid gland? C6
What is the arterial blood supply to the lacrimal apparatus? Ophthalmic artery
Which of structures lies posterior to the femoral nerve in the femoral triangle? iliacus
Where do lesions below the dentate line drain? Lesions distal to the dentate line drain to the inguinal nodes.
From which structre is the tunica vaginalis derived from? The tunica vaginalis is derived from peritoneum, it secretes the fluid that fills the hydrocele cavity.
What is the reciprocal of absolute risk reduction? Number needed to treat
What is the sensory nerve supply to the angle of the jaw? Greater auricular nerve (C2-C3)
Which of the fascial layers will be divided during the surgical approach to the axilla? Clavipectoral fascia
A 25 year old man is undergoing respiratory spirometry. He takes a maximal inspiration and maximally exhales. Which of the following measurements will best illustrate this process? Vital capacity
A 17-year-old girl presents with a swelling over her right knee. Movements of her knee are restricted. A plain x-ray of the affected site shows multiple lytic and lucent lesions with clearly defined borders. What is the most likely diagnosis? OSteoclastoma
What is the largest branch of the brachial artery? Profunda brachii artery
A 38 year old lady is due to undergo a parathyroidectomy for hyperparathyroidism. At operation the inferior parathyroid gland is identified as being enlarged. A vessel is located adjacent to the gland laterally. This vessel is most likely to be the: Common carotid artery
A 23 year old man presents with blunt abdominal trauma and a splenic bleed is suspected. He is commenced on an infusion of tranexamic acid. Which of the following best describes its mechanism of action? Inhibition of plasmin
Which of the following muscles inserts onto the lesser tuberostiy of the the humerus? Subscapularis
Approximately what proportion of salivary secretions is provided by the submandibular glands? 70%
Which nerve wraps around Wharton's Duct? Lingual nerve wraps around Wharton's duct.
Which of the following nerves conveys sensory information from the laryngeal mucosa? Laryngeal branches of the vagus
What is the function of sartorius? Flexor of the hip and knee, slight abducts the thigh and rotates it laterally It assists with medial rotation of the tibia on the femur. For example it would play a pivotal role in placing the right heel onto the left knee
Which of the following structures passes through the quadrangular space near the humeral head? Axillary nerve
A 22 year old lady presents with symptoms and signs of hyperthyroidism. Her diagnostic work up results in a diagnosis of Graves disease. Which of the following best describes the pathophysiology of the condition? Formation of IgG antibodies to the TSH receptors on the thyroid gland
What is omphalitis? This condition consists of infection of the umbilicus with Staph a. may spread rapidly through the umbilical vessels in neonates with a risk of portal pyaemia, and portal vein thrombosis.
Which of the following structures separates the ulnar artery from the median nerve? Pronator teres
How is aanatomical dead space measured? Anatomical dead space is measured by helium dilution
Which nerve supplies abductor pollicis longus? radial nerve
Which of the following structures separates the posterior cruciate ligament from the popliteal artery? Popliteus tendon
Brown tumours of bone are associated with which of the following? Hyperparathyroidism
Through which of the following foramina does the genital branch of the genitofemoral nerve exit t Deep inguinal ring
In which electrosurgical mode is the electrode held away from the tissue, where the current utilises a low amplitude and high voltage? fukgration
How long will it take for the serum PTH levels to fall if the functioning adenoma has been successfully removed?he abdominal cavity? 10 minutes
A 56 year old man is left impotent following an abdomino-perineal excision of the colon and rectum. What is the most likely explanation? Damage to the hypogastric plexus during mobilisation of the inferior mesenteric artery
What do central chemoreceptors respond to? Central chemoreceptors: Respond to increased H+ in BRAIN INTERSTITIAL FLUID to increase ventilation.
A 54 year old lady has her serum calcium measured. Assuming her renal function is normal, what proportion of calcium filtered at the glomerulus will be reabsorbed by the renal tubules? 95%
What causes glucagon release? Glucagon is a protein comprised of a single polypeptide chain. Produced by alpha cells of pancreatic islets of Langerhans in response to hypoglycaemia and amino acids. It increases plasma glucose and ketones.
What is the main component of colloid in the thyroid gland? thyroglobulin
Which of the following stimulates prolactin release or action? Thyrotropin releasing hormone
A 39 year old lady has recurrent attacks of biliary colic. What is the approximate volume of bile to enter the duodenum per 24 hours? 500ml
Which one of the following would cause a rise in the carbon monoxide transfer factor (TLCO)? Pulmonary haemorrhage
Which receptor does noradrenaline mainly bind to? a1
Which of the following is responsible for the rapid depolarisation phase of the myocardial action potential? Rapid sodium influx
Which ligament keeps the head of the radius connected to the radial notch of the ulna? Annular (orbicular) ligament
At which of the following vertebral body levels does the common carotid artery typically bifurcate into the external and internal carotid arteries? c4
A 19 year old man is playing rugby when he suddenly notices a severe pain at the posterolateral aspect of his right thigh. Which of the following muscle groups is most likely to have been injured? Long head of biceps femoris
Which of the following overlies the outer muscular layer of the intrathoracic oesophagus? Loose connective tissue
Which nerve lies medially on the thyroid gland, in the groove between the oesophagus and trachea? Recurrent laryngeal nerve
Which of the following nerve roots contribute nerve fibres to the ansa cervicalis? c1,c2,c3
A 23 year old lady is undergoing a trendelenberg procedure for varicose veins. During the dissection of the saphenofemoral junction, which of the structures listed below is most liable to injury? The deep external pudendal artery runs under the long saphenous vein close to its origin and may be injured.
A 28 year old man has a pleomorphic adenoma and the decision is made to resect this surgically. Which of the following structures is least likely to be encountered during surgical resection of the parotid gland? Mandibular nerve
Which of the nerves listed below is at greatest risk of injury with a laceration to the upper lateral margin of the popliteal fossa? Common peroneal nerve
What supplies the posterior scalp? C2,C3`
n inspecting the caecum, which of the following structures is most likely to be identified at the point at which all the tenia coli converge? Appendix base
A 36 year old male is admitted for elective surgery for a lymph node biopsy in the supraclavicular region. Post operatively the patient has difficulty shrugging his left shoulder. What is the most likely reason? Accessory nerve lesion
Which cranial nerve supplies the motor fibres of styloglossus? The hypoglossal nerve supplies motor innervation to all extrinsic and intrinsic muscles of the tongue. The only possible exception to this is palatoglossus, which is jointly innervated by the vagus and accessory nerves.
What is the normal angle between the femoral neck and the femoral shaft? 130
Which of the following bones is related to the cuboid's distal articular surface? 5th metatarsal
Which of the following nerves is responsible for the innervation of the posterior belly of the digastric muscle? Facial nerve
A 19 year old man undergoes an open inguinal hernia repair. The cord is mobilised and the deep inguinal ring identified. Which of the following structures forms its lateral wall? Transversalis fascis
What is the lymphatic drainage of the membranous urethra? Internal iliac nodes
In a patient with an ectopic kidney where is the adrenal gland most likely to be located? In its usual position
Which cranial nerve provides general sensation to the anterior two thirds of the tongue? Trigeminal
When performing minor surgery in the scalp, which of the following regions is considered a danger area as regards spread of infection into the CNS? Loose areolar tissue
Which of the following structures are at risk of direct injury following a fracture dislocation of the femoral condyles? Popliteal artery
An 82 year old lady presents with a carcinoma of the caecum. Approximately what proportion of patients presenting with this diagnosis will have synchronous lesions? 5%
Which of the following is a recognised tributary of the retromandibular vein? Maxillary vein
mydriasis and diminished direct response to light shone into the affected eye. The consensual response is preserved when light is shone into the unaffected eye. Which of the cranial nerves listed below is responsible for this? Optic nerve
A 28 year old man presents with hypertension and haematuria. Haematological investigations show polycythaemia but otherwise no abnormality. CT scanning shows a left renal mass. What is the most likely cause? Renal adenocarcinoma
A 63 year old man is undergoing a right pneumonectomy for carcinoma of the bronchus. As the surgeons approach the root of the lung, which structure will lie most posteriorly (in the anatomical plane)? Vagus nerve
A 43 year old lady is undergoing an axillary node clearance for breast cancer. The nodal disease is bulky. During clearance of the level 3 nodes there is suddenly brisk haemorrhage. The most likely vessel responsible is: Thoracoacromial artery
A 22 year old is found to have bilateral acoustic neuromas. Which of the disorders listed below is most likely to be present? Neurofibromatosis Type II
Which of the following fingers is not a point of attachment for the palmar interossei? Middle finger
He is well for several months and then develops symptoms of palpitations and facial flushing. Which of the following diagnostic markers should be requested? Urinary 5-Hydroxyindoleacetic acid measurements
A 33 year old man sustains an injury to his forearm and wrist. When examined in clinic he is unable to adduct his thumb. What is the most likely underlying nerve lesion? Deep branch of the ulnar nerve
A 6 year old sustains a supracondylar fracture of the distal humerus. There are concerns that the radial nerve may have been injured. What is the relationship of the radial nerve to the humerus at this point? Anterolateral
Which of the following structures does not pass anterior to the lateral malleolus? Peroneus brevis
A neonate is noted to have colonic obstruction, what is the most likely cause? Meconium plugs
A 4 year old boy is brought to the clinic by his mother. He has a swelling in his right hemiscrotum. On examination, it transilluminates brilliantly. What is the best course of action? Division of the patent processus vaginalis via an inguinal approach
A 16 year old man sustains a basal skull fracture and is suspected of having CSF rhinorrhoea. Which of the following laboratory tests would most accurately identify whether CSF is present or not? Beta 2 transferrin assay
What proportion of patients presenting for cholecystectomy for treatment of biliary colic due to gallstones will have stones in the common bile duct? 10%
Which of the following has the greatest impact on the positive predictive value of a test? Prevalence
During an open Watsons Fundoplication, the inferior pole of the spleen is injured causing troublesome bleeding. What is the best course of action? Use of argon plasma coagulation system
A 72 year old lady has a 4cm basal cell carcinoma excised from her right cheek. There is a rhomboid defect measuring 4cm by 4cm. What is the best option for managing the wound? Full thickness skin graft
A 6 year old boy presents with symptoms of recurrent pruritus ani. On examination, there is evidence of a small worm like structure protruding from the anus. What is the most likely infective organism? Enterobius vermicularis
A 68 year old women with previous rheumatic fever is admitted with pyrexia of unknown origin. Her blood cultures are unhelpful but transoesophageal echocardiography reveals vegetations on the mitral valve. Infectionis most likely? Staph viridans
A cohort study is being designed to look at the relationship between smoking and breast cancer. What is the usual outcome measure in a cohort study? Relative risk
What type of virus is Hepatitis B? Double stranded DNA virus
What is the commonest cause of an amoebic liver abscess? Entamoeba histolytica
A 56 year old lady is admitted with colicky abdominal pain. A plain x-ray is performed. Which of the following should not show fluid levels on a plain abdominal film? descending colon
A 55 year old man has multiple stones of varying size located within the renal pelvis. What is the most appropriate course of action? Arrange a percutaneous nephrolithotomy
A 28 year old man presents with a recurrent inguinal hernia on the left side of his abdomen and a newly diagnosed inguinal hernia on the right side. What is the best course of action? Laparoscopic hernia repairs are specifically indicated where there are bilateral hernias or recurrence of a previous open repair.
Created by: laylag
 

 



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