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Biochemistry LO1
Structure and function of biological molecules
| Term | Definition |
|---|---|
| Nucleic Acids | Macromolecules built up from nucleotide subunits which are joined together to form long unbranched chains. |
| What are the two types of nucleic acid? | Deoxyribonucleic acid (DNA) & ribonucleic acid (RNA) |
| What are the nucleotide subunits? | A pentose sugar, a nitrogenous base and a phosphoric acid |
| What pentose sugar is found in RNA? | A ribose sugar that has 5 oxygen atoms and the formula of C5H10O5 |
| What pentose sugar is found in DNA? | A deoxyribose sugar that has 4 oxygen atmons (lacking an oxygen on carbon 2) and has a formula of C5H10O4 |
| What are the two purine bases? | Adenine and Guanine |
| What are the three pyrimidine bases? | Cytosine, Thymine (DNA) and Uracil (RNA) |
| There is two condensation reactions to form a nucleoside and then a nucleotide, what type of reactions are these? | Condensation reactions, which both form strong covalent bonds |
| During the formation of a nucleoside, what bond forms? (carbon 1 of the sugar and the nitrogenous base) | N-glycosidic bond |
| What bond forms in the formation of a nucleotide ( carbon 5 of the sugar and the phosphate) | Phosphoester bond |
| What is DNA a polymer of? | Deoxyribonucleotides |
| Nucleotides are joined by carbon-3 of the pentose sugar of one nucleotide and the phosphate group of the next nucleotide, producing a sugar phosphate backbone. What kind of bond joins them? | Covalent bonds |
| The formation of the polynucleotide by a series of condensation reactions results in a which bond forming? | Phosphodiester bond. |
| How many hydrogen bonds are between adenine and thymine? | Two |
| How many hydrogen bonds are between guanine and cytosine? | Three |