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Mlt renal test
| Question | Answer |
|---|---|
| A decrease in this protein will result in an emphysema-like condition. | alpha1- antitrypsin |
| A protein that is increased or normal in nephrotic syndrome is | alpha2- macroglobulin |
| A technologist obtains a BUN value of 61 mg/dL and a serum creatinine value of 3.5 mg/dL on a patient. The BUN/creatinine ratio indicates | Renal Failure |
| All of the following conditions are associated with hyperuricemia | malignancy, renal failure, and primary "essential" overproduction of uric acid |
| an elevated BUN usually indicates | Kidney disease |
| Bromcresol Green (BCG) may be used in the dye-binding assay of | albumin |
| Ceruloplasmin is an alpha2-globulin that contains | copper |
| creatinine is formed from the | oxidation of creatine |
| creatinine reacts with strong alkaline picrate to form a yellow-red compound. This reaction is | Jaffe reaction |
| Dipstick reactions for blood are based on | the peroxidase activity of hemoglobin |
| high serum total protein but low albumin is usually seen in | multiple myeloma |
| in agarose gel electrophoresis of human serum at pH 8.6, the slowest moving fraction is | gamma-globulin |
| in an acute phase reaction (M.I., etc.) there is a(n) | Decrease in albumin, increase in alpha1-globulin, alpha2-globulin, and alpha3-globulin |
| Increased uric acid is found in each of the following conditions | gout, Lesch-Nyhan syndrome, renal failure |
| Leukocyte reagent strips are used to detect leukocyte | esterases |
| Myeloma (bence-jones) protein is most often found electrophoretically in the area of | gamma-globulins |
| normal values for urea are generally expressed as urea nitrogen. If it is necessary to convert urea nitrogen values to urea, the concentration may be calculated easily by multiplying the urea nitrogen value by | 2.14 |
| protein is approximately _________ nitrogen | 16% |
| Renal azotemia is found in | nephrotic syndrome |
| serum urea nitrogen and serum creatinine determinations are frequently requested together so that their ratio may be evaluated. what is the range of the normal ratio of urea nitrogen to creatinine? | 12/1 and 20/1 |
| The chemical bond between amino acids in the primary structure of proteins are | peptide bonds |
| the chief source of error in kidney evaluation using the excretion rate of substance is | the timing and completeness of collection |
| the common ingredients of all biuret reagents are | sodium potassium tartrate, copper sulfate, and sodium hydroxide |
| the principal protein for transport of iron from the intestine to the liver, bone marrow, or spleen for storage is | transferrin |
| the protein section of the reagent strip is most sensitive to | albumin |
| Uric acid may be determined with | both the enzyme uricase and formation of a blue color with phosphotungstic acid |
| which condition is associated with the fusion of the betta-gamma bridging | cirrhosis |
| which condition is associated with massive proteinuria | nephrotic syndrome |
| which is the most abundant gamma-globulin | IgG |
| what condition is usually associated with an acute inflammatory pattern | myocardial infarction |
| what is not an NPN substance | Troponin T |
| what is one of the proteins that is part of the coagulation cascade? | fibrinogen |
| while scanning the chemistry results on several patients, a tech discovers that Mr.Bob's BUN was 15 mg/dL and his creatinine was 5.0 mg/dL. The tech should | repeat both tests because the results do not correlate |
| where are most proteins synthesized | in the liver |
| which protein fraction normally accounts for 50-65% of the total protein | albumin |
| why is the biuret method not suitable for CSF and urine protein testing | method is not sensitive at low levels |
| At a pH of 8.6 proteins are __________ charged | negatively |
| At a pH of 8.6 proteins migrate toward the | anode |
| Alpha-1 antitrypsin typically migrates to | the alpha 1 region |
| Beta-2 macroglobulin typically migrates to | the beta region |
| C-reactive protein typically migrates to | the beta region |
| ceruloplasmin typically migrates to | the alpha 2 region |
| fibrinogen typically migrates to | the beta region |
| Immonoglobulins (IgG, IgM, ect,) typically migrate to | the gamma region |
| Haptoglobin typically migrates to | the alpha 2 region |
| transferrin typically migrates to | the beta region |
| the complement protein typically migrates to | the beta region |
| what is alpha-1 antitrypsin's function/description? | it inhibits proteolytic enzymes; decreased in congenital emphysema |
| what is beta-2 macroglobulin's function/description? | sensitive indicator of renal nephropathy in diabetes |
| What is C-reactive protein's (CRP) function/description? | acute phase reactant that is used as a non specific marker of inflammatory conditions |
| what is ceruloplasmin's function/description? | transports copper and Is an acute phase reactant |
| What is fibrinogen's function/description? | coagulation factor |
| what is haptoglobin's function/description? | binds and transports free hemoglobin; decreased in hemolytic episodes |
| what is IgG's function/description? | most abundant immunoflobulin in serum |
| what is IgM's function/description? | largest immunoglobulin; increased in Waldenstrom's macroglobulinemia |
| What is prealbumin's function/description? | used to evaluate nutritional status |
| What is transferrin's function/description? | transports iron |
Created by:
Mwortman