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Ch 33
| Question | Answer |
|---|---|
| B cells and T cells are examples of: | lymphocytes |
| Cell-mediated immunity involves: | T cells. |
| The T cell subsets that are clinically important in diagnosing AIDS are: | CD4 and CD8. |
| An antibody consists of: | two heavy and two light polypeptide chains |
| The amount of antibodies in a person’s blood in response to exposure to a pathogen is called: | titer. |
| The most abundant circulating antibody is: | IgG. |
| The specific cells that secrete antibodies are: | plasma cells. |
| T cells are sensitized by: | presentation of an antigen by an antigen- presenting cell. |
| Complement can best be described as: | an enzyme in the blood plasma. |
| The chemical messengers that T cells release into inflamed tissues are called: | cytokines. |
| Antibodies are proteins of the family called ___________________. | Immunoglobulin |
| _______________ is the predominant class of antibody produced after initial contact with an antigen. | IgM |
| The first vaccination was against the _______________ ______________ | Cowpox virus |
| Some vaccines use ___________________ (weakened) pathogens. | Attenuated |
| _________________ ___________________ generally lasts longer than passive immunity. | Active immunity |
| Abnormal antigens or _________________ __________________ are present in the plasma membranes of some cancer cells in addition to self-antigens. | Tumor markers |
| _______________ is elevated in both benign and malignant prostate disease. | PSA |
| Helper T cells and suppressor T cells help regulate ___________________ ___________________ function by regulating B cell and T cell function. | Adaptive immune |
| A fetus receives protection from the mother through ___________________ ___________________ immunity. | Natural passive |
| A vaccination provides _________________ _________________ immunity. | artificial active |
| ______ Stem cells are missing or unable to grow properly | SCID |
| ______ Retrovirus | HIV |
| ______ Inhibits symptoms of AIDS | AZT |
| ______ Chronic autoimmune inflammatory disease of the joints, blood vessels, skin, kidney, and nervous system | SLE |
| _____ Involved in transplant rejection | HLAs |
| T cells do which of the following? | develop in the thymus |
| Acquired immune deficiency syndrome is characterized by which of the following? | all of the above |
| B cells do which of the following? | all of the above |
| Which of the following kills invading cells by drilling a hole in their plasma membrane? | complement |
| What is a rapidly growing population of identical cells that produce large quantities of specific antibodies called? | monoclonal |
| Which of the following is a form of passive natural immunity? | An infant receives protection through its mother’s milk. |
| Hypersensitivity of the immune system to an environmental antigen is known as an ___________________. | Allergy |
| Drugs used to relieve the symptoms of allergies are called ___________________. | antihistamines |
| Adaptive immunity is also known as __________________ ___________________. | specific immunity |
| A ___________________ is a powerful poison that acts directly and quickly to kill any cell it attacks. | lymphotoxin |
| The human immunodeficiency virus has a profound impact on a person’s number of CD12 subset of T cells. T or F? | False |
| Once inside a cell, HIV uses its viral RNA to produce DNA; this process is called reverse transcription. T or F? | True |
| A common autoimmune disease is SLE or “lupus.” T or F? | True |
| SCID is an immunosuppressive drug. T or F? | False |
| Glomerulonephritis is an autoimmune disease of the neuromuscular junction. T or F? | False |
| Antibody-mediated immunity is sometimes referred to as (humoral or cellular) immunity. | Humoral |
| Antibodies are proteins of the family called (lymphotoxins or immunoglobulins). | immunoblobins |
| Complement attacks antigens by (cytolysis or clonal deletion). | cytolysis |
| The chemical messengers released by T cells are called (interleukins or cytokines) | cytokines |
| Vaccinations are (active or passive) forms of gaining immunity. | active |