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Dental Anatomy.1

Tooth Development

QuestionAnswer
Odontogenesis Tooth development
What are the stages of tooth development? Initiation, Bud, Cap, Bell, Apposition & Maturation
When does the primary dentition develop? During both the embryonic & fetal periods.
When is the permanent dentition formed? Most of it is formed during the fetal period but tooth development continues for years after birth until the 2nd or 3rd molars are formed.
What takes place during the initiation stage? INDUCTION (6th - 7th wk)mesenchymal tissues must influence the ectodermal tissues in order for initiation of odontogenesis to occur.
What does the outer portion of the ectoderm that lines the primitive mouth give rise to (become)? The oral epithelium. (two bands of tissue--the future arches)
What forms deep in the oral epithelium by neural crest cells that have migrated to the area? Ectomesenchyme
What separates the oral epithelium & the ectomesenchyme? The basement membrane.
What is the new layer of epithelium that is formed as the oral epithelium grows deeper into the ectomesenchyme? And where does it start to form? Dental lamina -- it starts to form in the midline of both arches & progresses posteriorly.
What is the second stage of odontogenesis? BUD STAGE (8th wk)
What is the main process involved in the bud stage? PROLIFERATION(growth) of the dental lamina into buds that penetrate into the ectomesenchyme.
What structural changes occur during the bud stage? None, there is only proliferation (or growth) of the tissues during this stage.
What is the third stage of odontogenesis called? Cap stage (9th - 10th wk)
What main processes are involved in the cap stage? Proliferation, differentiation, Morphogenesis
What is the predominant physiological process during the cap stage? morphogenesis
What forms in the deepest part of each tooth bud of dental lamina? Enamel organ (or a cap)
What is the role of the enamel organ? It will produce enamel.
What type of product is enamel? (endoderm, ectoderm, mesoderm?) It is an ectodermal product -- because the enamel organ was originally derived from ectoderm.
Dental papilla? A dense, ectomesenchyme tissue within the concavity of the cap of the enamel organ.
What will the dental papilla produce in the future? Dentin & pulp tissue for the inner portion of the tooth.
What type of product are dentin & pulp tissue? mesenchymal -- because the dental appilla is originally derived from ectomesenchyme which is influenced by neural crest cells.
What structure is between the enamel organ & dental papilla? The basement membrane.
What does the basement membrane become? The dentinoenamel junction.
What happens to the remaining ectomesenchyme surrrounding the outside of the cap (enamel organ)? It condenses and takes on a capsulelike appearence it's called -- DENTAL SAC
What will the dental sac produce in the future? The periodontium-- the supporting tissues of the tooth: cementum, periodontal ligament & alveolar bone
What type of product are the supporting dental tissues? Mesenchymal -- the dental sac is originally derived from ectomesenchyme.
Tooth germ? And when is it present? The enamel organ, dental papilla, & dental sac. (These embryological structures are all formed by the end of the cap stage)
What is the fourth stage of odontogenesis? Bell Stage (11 - 12th wk)
What processes are involved in the bell stage? continuation of proliferation, differentiation, & morphogenesis
What is the most prodominant process of the bell stage? DIFFERENTIATION -- ENAMEL ORGAN now has four different types of cells -- so the enamel organ takes on a bell shape -- dental papilla (W/I the concavity of the enamel organ) now consists of two types of tissues or layers
Name the 4 types of cells found in the enamel organ during the bell stage. *Inner enamel epithelium *Outher enamel epithelium * stellate reticulum *stratum intermedium
OEE *outer cuboidal cells of the enamel organ *protective barrier of the enamel organ during enamel production
IEE *innermost tall columnar cell of the enamel organ * will differentiate into ameloblasts that form enamel matrix
Stellate reticulum *star-shaped network of cells *more outer middle layer of the enamel organ *support the production of enamel
Stratum intermedium *compressed layer of flat to cuboidal cells *more inner middle layer of the enamel organ *support the production of enamel.
Outer cells of the dental papilla *layer of the dental papilla *will differentiate into dentin-secreting cells (odontoblasts)
Central(or Inner) cells of the dental papilla differentiates into pulp tissue
Dental sac during the bell stage. *increasing amt of collagen fibers forming around the enamel organ * will differentiate into cementum, periodontal ligament, & alveolar bone
What is the fifth stage of odontogenesis? Apposition
What happens during the apposition stage? Enamel, dentin, & cementum are secreted in successive layers. SECRETED AS A MATRIX
Matrix an extracellular substance that is partially calcified yet serves as a framework for later calcification.
What processes are involved in the apposition stage? Induction & proliferation
What is the 6th stage of odontogenesis? Maturation -- when the dental tissues fully mineralize to their mature levels.
What is the role of the basement membrane? *It serves as a boundary between the cells of the enamel organ & the dental papilla *It also conveys communications between between enamel organ, dental papilla & dental sac allowing these tissue interations
List the events in the production of enamel & coronal dentin. *The formation of preameloblasts, *odontoblasts, *dentin matrix, *ameloblasts *dentinoenamel junction *enamel matrix
Cellular repolarization It is the movement of all the nuclei in the IEE cells to the position farthest away from the basment membrane. This changes IEE cells into preameloblasts.
What is the role of preameloblasts? They will induce dental papilla cells to differentiate into odontoblasts.
Repolarization of odontoblasts. The nuclei of the odontoblasts move from the center to a position in the cell farthest from the basment membrane.
dentinogenesis Odontoblast make dentin matrix (or predentin) on their side of the basement membrane.
Why is the dentin layer in any location in a developing tooth slightly thicker than the corresponding layer of enamel matrix? Because the odontoblasts start making dentin before the ameloblast start making enamal.
What makes the preameloblast differentiate into ameloblasts? The basment membrane disintegrates so the preameloblasts come into contact with dentin that the odontoblasts produced this induces the preameloblast to differentiate into ameloblasts.
Amelogenesis? Ameloblasts lay down enamel matrix on their side of the now disintegrating basement membrane.
Tomes' process A tapered portion of each ameloblast where enamel matrix is secreted from. It faces the disintegrating basement membrane.
Dentineonamel Junction (DEJ) Mineralization of the disintegrating basement membrane marks the inner junction between the dentin & enamel tissues
Attached cellular extensions in the length of the predentin that odontoblasts leave. Odontoblastic process
Where are odontoblastic processes contained? Dentinal tubule --a mineralized cylinder
What happen to the cell bodies of odontoblasts? The will remain within pulp tissue.
What will become of cell bodies of the ameloblasts? They will be involved in the eruption and mineralization proces but will be lost after eruption.
When does root deveopment take place? After the crown is completely shaped & the tooth is starting to eruptinto the oral cavity.
What structure is responsible for root development? Cervical loop
Cervical loop? *is the most cervical portion of the enamel organ, *a bilayer rim that consists only of IEE & OEE
HERS Hertwig's epithelial root sheath *a membrane that shapes the root & induces dentin formation in the root area so that it is continueous with coronal dentin.
Where does HERS come from? *it is formed by the cervical loop from dental papilla tissue (the cerv. loop grows deeper into the ectomesenchyme of the dental sac, elongating & moving away from the newly completed crown to enclose more of the dental papilla tissue and forms HERS)
Why isn't there enamel in the root? HERS induces odontolastic differentioation but doesn't induce enamel-forming ameloblasts.
Why doesn't HERS induce ameloblasts? Because HERS consists only of the OEE & IEE it does not contain Stratm intermedium & Stellate reticulum.
What happens to the root sheath after root dentin formation is complete? HERS is disintegrated and the basement membrane that seperates the the IEE & odontoblasts of the root area.
What happens to the cell bodies of HERS? These groups of epithelial cells become located in the mature periodontal ligament. (they can become cystic later and cause problems)
Enamel pearls? Small spherical enamel projections on the root surface from misplaced ameloblasts. (usually in CEJ area or fucation area if present)
What happens when undifferentiated cells of the dental sac come in contact with newly formed surface of root dentin? The undifferentiated cells are induced to become immature CEMENTOBLASTS & cementogenesis begins.
Cementogenesis? cementoblasts move to cover the root dentin & lay down a cementum matrix(also called cementoid)
Cementocytes? Cementoblasts that become entrapped by the cementum the produce.
Cementum? Calcification of cementocytes that are surrounded by the cemntoid (the cementum matrix)
DEJ Dentinoenamel junction -- Junction between the dentin & enamel formed by the mineralization of the disintegrating basement membrane.
Periodontal ligament? (PDL) is the ligament surrounding the teeth that supports & attaches the teeth to the bony surface of teh alveoli.
How is the PDL developed? Collagen fibers are formed for the ectomesenchyme of the dental sac.
Where are the collagen fibers of the PDL located? One end of the fiber bundles is inserted into the outer portion of the cementum & the surrounding alveolar bone to support the tooth.
Alveolar bone? Tooth sockets formed by the mineralization of the ectomesenchyme of the dental sac.
Concrescence? The roots of 2 or more teeth join as a result of excessive cementum deposition.
Describe the development of a root with more than one root branch. The cervical loop of the enamel organ elongates & horizontal epithelial extensions develop which divides the usual single cervical opening into two or three openings.
Created by: riosalado
 

 



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