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AP2 Blood
Blood
| Question | Answer |
|---|---|
| Albumins regulate water movement between ___ and ___ ___ | blood, interstitial fluid |
| Fibrinogen is responsible for forming ___ ___ | blood clots |
| Dehydration means decreased ___. | plasma |
| Plasma is ___*% water. | 92 |
| The smallest and most abundant plasma proteins are ___. | albumins |
| Erythrocyte is a formed element because it lacks a ___ and ___ | nucleus, organelles |
| Leukocyte that is S-Shaped, Secretes histamine & Heparin | basophil |
| Leukocyte very active during bacterial infection. First WBC to respond to tissue damage | neutrophil |
| Leukocyte that will migreate in blood and become macrophages. | monocyte |
| The life span of an erythrocyte is ___ days. | 120 |
| Plasma is similar to interstitial fluid in that it has similar concentrations of ___ and ___. | nutrients, electrolytes |
| _________ are proteins produced by white blood cells, aka B-lymphocytes. | Antibodies |
| ______________, a hormone, stimulates megakaryocyte production in bone marrow and formation of platelets. | Thrombopoietin |
| Thrombocytopenia is an abnormally small number of ___. | platelets |
| Type A blood has what antigen? | A only |
| Type B blood has what antigen | B only |
| Type AB blood has what antigen | Both A and B |
| Type O blood has what antigen | none (neither a nor b) |
| Type A blood has what Antibodies? | B Antibodies in the plasma |
| Type B blood has what Antibodies | A Antibodies in the plasma |
| Type AB blood has what Antibodies | No Antibodies in the plasma |
| Type O blood has what antibodies | BOTH A & B Antibodies in the plasma |
| Universal Blood RECIPIENT has what blood type | AB+ |
| Universal blood DONOR has what blood type | O- |
| inhibits blood clot formation | Heparin |
| The process of engulfing & ingesting microorganisms, antigens, and cellular debris (“cell eating”) | Phagocytosis |
| Anything foreign (non-self), or perceived as foreign | Antigen |
| Phagocytes, cytoplasm appears 'grainular', multi-lobed nuclei | Granulocytes |
| Cytoplasm does not appear granular, single-lobed nuclei | Agranulocytes |
| The Composition of Whole Blood: plasma proteins, other solutes and water make up | Plasma |
| The Composition of Whole Blood: plasma makes up 46%-___% of blood | 63 |
| The Composition of Whole Blood: Plasma is ___% water | 92 |
| The Composition of Whole Blood: Formed elements of blood make up 37%- ____%of blood | 54 |
| The Composition of Whole Blood: 99% of formed elements of blood consists of | RBCs |
| The Composition of Whole Blood: Formed elements of blood include RBCs, Platelets, and ______ | WBCs |
| Stages of RBC Maturation: Day 1 | proerythroblast |
| Stages of RBC Maturation: Day 2 | basophilic erythroblast |
| Stages of RBC Maturation: Day 3 | polychromatophilic erythroblast |
| Stages of RBC Maturation: Day 4 | Normoblast |
| Stages of RBC Maturation: Day 5-7 | Recticulocyte |
| Stages of RBC Maturation: nucleus is ejected on day | 4 |
| Found in circulating blood | Recticulocytes |
| is in the middle of each heme | Iron (Fe) |
| a plasma protein that transports iron ions in the plasma. | Transferrin |
| Antibodies against Rh antigen are only generated after a _____pregnancy. | first |
| become macrophages, which engulf pathogens. | Monocytes |
| reduce inflammation and release cytotoxic enzymes. | Eosinophils |
| stem cells differentiate separately from the myeloid stem cell, which gives rise to all the other blood cells. | Lymphoid |
| Which of the pathways will occur within a damaged vessel | Both the intrinsic and the common pathways |
| characteristic of all leukocytes | they are nucleated |
| Blood is classified as a(n) __________ tissue | Connective |
| Visible cytoplasmic granules are NOT present in | monocytes |
| When viewing a blood smear under a microscope, the cells with the visible nuclei are ___________. | leukocytes |
| ________________ is the substance of the red blood cell (erythrocyte) that binds to oxygen and carbon dioxide. | Hemoglobin |
| granular leukocytes (BEN) | Basophils, Eosinophils, and Neutrophils |
| Platelets, which are involved with blood clotting, are fragments of which cells? | Megakaryocytes |
| B cells and T cells are classified as | lymphocytes |
| When neither anti-A sera nor anti-B sera clump on a blood plate with donor blood, the blood is Type | O |
| may induce erythroblastosis fetalis | Rh-negative mother; Rh-positive fetus |
| Administering _____________ can prevent an Rh-negative mother from producing anti-Rh antibodies (anti-D) following exposure to the Rh antigen. | RhoGam |
| A ________________ measures the percentage of total blood volume that is occupied by red blood cells. | Hematocrit test |
| The normal hematocrit for a woman is between 37% and 47%. A hematocrit of 25% indicates | anemia |
| A low hematocrit would impair | Oxygen transport |
| During coagulation, insoluble protein threads called ___________ trap platelets to help form a clot. | Fibrin |
| Heparin is an ________________that can be administered to patients to prevent blood clotting or can be used to prevent blood clotting in clinical equipment and tubing, such as those used for dialysis and open heart surgery. | anticoagulant |
| A patient with a slower-than-normal coagulation time might be at risk for | Hemorrhage |
| The heme units of old RBCs are converted into ____________________. | biliverdin |
| If you have type A blood, your plasma holds circulating __________ that will attack __________ erythrocytes. | anti-B agglutinins; Type B |
| The plasma proteins found in the highest concentrations are ____________________. | albumins |
| The rate of platelet formation is regulated by ____________________. | Thrombopoeitin, interleuikin, and Multi-CSF |
| In addition to water and proteins, the plasma consists of: | electrolytes, nutrients, and organic wastes |
| Monocytes leave the circulation to become ____________________. | macrophages |
| The part of the hemoglobin molecule that directly interacts with oxygen is: | the iron ion |
| The major components of whole blood are ____________________. | plasma and formed elements |
| Erythropoiesis occurs in ____________________. | red bone marrow |
| contain histamine that exaggerates the inflammation response at the injury site | Basophils |
| The three primary classes of plasma proteins are: | albumins, globulins, fibrinogen |
| The most abundant blood cells are ____________________. | erythrocytes |
| Plasma cells are responsible for ____________________. | antibody production |
| The plasma protein which plays an important role in blood clotting is ____________________. | fibrinogen |
| The process of hemostasis includes the ____________________. | Vascular phase, Platelet phase, Coagulation phase |
| The major components of the cardiovascular system are the: | blood, heart, blood vessels |
| The most common circulating white blood cells are ____________________. | neutrophils |
| Megakaryocytes are specialized cells of the bone marrow responsible for: | formation of platelets |
| The lifespan of a typical RBC is about ____________________. | four months |
| Formed elements of blood are produced through the process of | hemopoiesis/hematopoiesis |
| Normal blood volume for a male adult: | 5-6 Liters |
| Normal blood volume for a female adult: | 4-5 Liters |
| PH of blood | 7.35-7.45(alkaline) |
| temperature of blood | 100.4 F/38 C |
| hormone binding proteins, Metalloproteins, Apolipoproteins, and steroid-binding proteins are examples of transport | globulins |
| A patient has an infected puncture wound to her foot. Which type of white blood cell would you expect to be elevated in a differential white cell count? | neutrophils |
| A person's blood type is determined largely by the presence of ____________ ____________ on the cell membrane | specific glycoproteins |
| People with type AB blood are considered the "universal recipient" for transfusions because their blood lacks A or B | agglutinins |
| Eosinophils function in destroying | antibody-labeled antigens |
| The blood cells involved in specific immunity are the: | lymphocytes |
| The function of platelets is to assist in the process called | hemostasis |
| During a bacterial infection you would expect to see increased numbers of |