click below
click below
Normal Size Small Size show me how
Cell Bio
Beginning
| Question | Answer |
|---|---|
| When you multiply exponents, you _______ exponents | add |
| When you divide exponents, you _________ exponents | subtract |
| Milli | 10^-3 |
| Micro | 10^-6 |
| Nano | 10^-9 |
| Hydrogen and water are ______________ whereas water is a _________________ | elements; compound |
| Weight/formula weight = ? | mole |
| H and O are discrete particles called what? | atoms |
| H20 is a ____________, meaning it consists of a discrete particle made of atoms stuck together by _________ bonds | covalent |
| Atomic weight refers to what? | Weight of the element/atom |
| Molecular weight refers to what? | Weight of the molecule/compound |
| What is the mass of a proton? | 1 amu |
| What is the mass of a neutron? | 1 amu |
| The number of protons per atom refers to what? | Atomic number |
| The sum of the number of protons and neutrons per atom refers to what? | Atomic weight or mass |
| How many grams does one proton or neutron weigh? | 1/6.02x10^23 grams |
| 6.02x10^23 neutrons or protons weighs what? | 1 gram |
| Since a hydrogen atom has only one proton, the weight of one mole of H is ? | 1 gram |
| The weight of one mole of anything else weighs one gram times what? | the total number of protons and neutrons per nucleus |
| What have a concentration of 1 mole of the substance in 1 liter of solution? | Molar solution |
| A _________ is X grams of a substance where X is its relative molecular mass | Mole |
| Solute + _________ = solution | Solvent |
| The idea that atoms can separate into negative and positive parts (proposed by Faraday) | Ionization |
| What can spontaneously move from one water molecule to another, creating two ionic species? | Positively charged Hydrogen ions |
| Pure water contains a steady-state concentration of ______________ ions and _____________ ions which are both 10^-7 M | hydrogen; hydroxyl |
| Substances that release hydrogen ions into solution | acids |
| A _____________ like HCl completely dissociates | strong acid |
| Many acids important in the cell are only partially dissociated, and are therefore ______________ | weak acids |
| All reactions are ______________ but some such as dissociation of NaOH are less so | reversible |
| Substances that reduce the number of hydrogen ions in solution | bases |
| Some bases such as ammonia combine ____________ with hydrogen ions | directly |
| Some bases such as sodium hydroxide reduce the number of H+ ions ______________, by making ____________ ions | indirectly; OH- |
| Many bases found in cells are partially dissociated and are called ____________ | weak bases |
| Compounds that contain an amino group (-NH2) which has a weak tendency to reversibly accept H+ ions from water are considered ____________________ | weak bases |
| -log [H+] = ? | pH |
| The acidity of a solution is defined by the concentration of _____________ it possesses | H+ ions |
| What is the pH of pure water? What is it's [H+] value? | pH of 7, [H+] is 10^-7 moles/liter |
| For each 1 unit pH increase, there is a ________ fold ____________ in [H+] | 10; decrease |
| The product of [H+] and [OH-] is always ______________ whether in a neutral, basic, or acidic solution | 10^-14 |
| -log [OH-] = ? | pOH |
| pH + pOH = ? | 14 |
| If the starting stock concentration was 1.0M, a 1/10 dilution makes it? | 0.1M |
| If 1.0ml of stock + 1.0ml water, it is called a _____________________ | 1/2 dilution |
| What structures are found in plant cells but not animals cells? | Chloroplasts, cell walls, fluid-filled central vacuole |
| cytosol + organelles = ? | cytoplasm |
| Sequence of genetic programming? (central dogma of bio) | DNA --> RNA --> Protein |
| What process makes RNA from DNA, and where? | Transcription, nucleus |
| What process makes protein from RNA, and where? | Translation, ribosomes |
| The section of DNA that codes for a specific protein is called what? | gene |
| Type of cell in which DNA exists free in the cell | Prokaryote |
| DNA that exists in a prokaryotic cell is in a clump called the ________________ | nucleotide |
| Type of cell in which DNA is in a membrane-bound nucleus | Eukaryote |
| Bacteria is what type of cell? | Prokaryotic |
| What are examples of eukaryotic cells that don't have a nucleus? | Red Blood cells, ER, golgi apparatus, mitochondria |
| What shape is the DNA of bacteria? | A Ring |
| What shape is the DNA in eukaryotes? | Rods |
| What type of cells can receive genetic material from others, but not a complete extra set? | Prokaryotes |
| Eukaryotes have more?/less? genetic material than prokaryotes? | More |
| Eukaryotes have their genetic material complexed with? | protein |
| At some stages, what type of cell can have more than one complete set of chromosomes (one maternal and one paternal?) | Eukaryotes |
| Microtubules and microfilaments are examples of what? Found in what type of cells? | Cytoskeletal structures, eukaryotes |
| What is the site of protein synthesis? | Ribosomes |
| What type of cells have larger ribosomes? | Eukaryotes |
| Eukaryotes divide by what process? | Mitosis |
| Prokaryotes divide by what process? | Simple fission |
| In cellular reproduction, what are features found in eukaryotes but not prokaryotes? | Compacted chromosomes, spindle apparatus, composed of microtubules |
| What are the three mechanisms of locomotion in eukaryotes? | Cytoplasmic movement, cilia, flagella |
| What is the mechanism of locomotion in prokaryotes? | Flagella (different in form and mechanism from eukaryotic) |
| What type of cells have membrane-bounded organelles? | Eukaryotes |
| What did Schleiden and Schwann propose? | All organisms are composed of cells, cell is the structural unit of life |
| What did Virchow propose? | Cells can arise only by division from a pre-existing cell |
| Who discovered cells by looking at cork through a compound microscope? | Robert Hooke |
| The process in which the cell membrane pulls away from the cell wall as the cell shrinks is called what? | Plasmolysis |
| What type of cells have plasmolysis? | Plant cells |
| What happens to the cell as water moves out? | It shrinks |
| What refers to plant cells with normal turgor pressure? | Hypotonic |
| What refers to plant cells with no turgor pressure? | Hypertonic |
| What do all cells have? | cell membranes, protoplasm (cytoplasm) |
| What does the nuclei break down into before the cell divides? | Chromosomes |
| What happens to chromosomes before the cell divides? | They split laterally |
| Where is genetic material found in the cell? | Nucleus and chromosomes |
| Sperm and eggs are _____________ cells. During fertilization, they fuse. | Single |
| What membrane-bound organelles are important for intracytoplasmic transport and packaging? | ER, golgi, lysosomes |
| What membrane-bound organelles are important for aerobic respiration? | Mitochondria |
| In plants, what organelles are important for photosynthesis? | Chloroplasts |
| What do prokaryotes have that connect their chromosomes to the plasma membrane? | Mesosomes |
| What membrane system does cyanobacteria have that are infoldings of the plasma membrane? | Photosynthetic membrane systems |
| Prokaryotic organisms are usually single-celled but can exist in ____________ ____________ | Multicellular groupings |
| What are examples of eukaryotic organisms that are single-celled? | yeast, protists |
| Different cells in a multicellular organism have the same _________________ (set of genetic information) | genome |
| As cells with the same genetic information _____________________, some genes are turned off. | Differentiate (specialize) |
| Eukaryotes ingest things by _____________________ and egest them by _____________________ | endocytosis; exocytosis |
| As cells endocytose, they take in their own ___________________________________ | plasma membrane |
| Since Eukaryotes are much bigger than prokaryotes, they need an _______________________ for intracellular transport | Internal membrane system |
| The membrane of a eukaryote pinches off and the surface fuses to form __________________ | internal membraneous vesicles |
| _______________________ is endocytosis of large food, such as other cells (eating) | Phagocytosis |
| ___________________ is endocytosis of small food and liquids (drinking) | Pinocytosis |
| What use oxygen to get maximal energy from their food during respiration? | Aerobes |
| Some, but not all, prokaryotes are (anaerobic?/aerobic?) | Aerobic |
| What do many prokaryotes use for respiration? | Plasma membranes |
| What theory attempts to explain why mito and chlor have both an outer and inner membrane? | Endosymbiant theory |
| Endosymbiotic theory says _________________ arose when an ancestral anaerobic cell engulfed an aerobic prokaryote | Mitochondria |
| Chloroplasts have _____________ membranes | double |
| Animal eukaryotes and somem prokaryotes are ______________ -- must eat other organisms | heterotrophic |
| __________________ can make their own food (some prokaryotes do this by using specializations of their plasma membranes) | Autotrophs |
| __________________ are thought to have arisen when an ancestral heterotrophic eukaryote engulfed autotrophic bacteria which survived inside the host, making the host cell autotrophic | Chloroplasts |
| Mitochondria and chloroplasts duplicate (independently?/dependently?) of the cell nucleus | Independently |
| Cells engulf other cells, symbiotic relationships are common, mitochondria and chloroplasts duplicate independently of the cell nucleus are evidence of what? | endosymbiotic theory |
| Mitochondria and chloroplasts have their own __________ and ______________, both of which are more similar to those of prokaryotes than to those of eukaryotes | DNA and ribosomes |
| Why are viruses not considered alive? | They have DNA but don't have the means to use it? |
| Any virus that infects a bacteria? | bacteriophage |
| Viruses are made up of? | Protein coat and nucleic acid (DNA or RNA) |
| Prokaryotic and eukaryotic cells have a similar appartus for conserving chemical energy as ___________ | ATP |
| Prokaryotes conserve chemical energy in the _________________________ | plasma membrane |
| Eukaryotes conserve chemical energy in the ______________________________________ | mitochondrial membrane |
| Cyanobacteria and green plants have similar mechanisms for what? | Photosynthesis |
| Viruses lack ___________, the cellular structures that provide the machinery for converting the genetic information from RNA | ribosomes |
| Viruses and cell parts CAN grow and produce ________________________, but cells can | in vitro |
| A proton or neutron has a mass of one ____________________ | dalton |
| All elements commonly found in living organisms have _______________________________________ and hence can participate in chemical reactions. | unfilled outermost shells |
| Covalent bonds have a definite _____________ so there is just the right amount of attraction | length |
| Covalent bonds have a definite _________ causing molecules to have definite shapes | orientation |
| CH3 | Methyl |
| H2PO3 | Phosphate |
| OH | hydroxyl |
| COOH | carboxyl |
| SH | sulfhydryl |
| In polar covalent bonds, electrons are shared _____________ | unevenly |
| O and N attract electrons less/more? strongly than C or H? | more |
| In water, H has a partial +/-? charge and O has a partial +/-? charge | +, - |
| In O2, electrons are shared ______________. This is a _________________ covalent bond. | Equally, nonpolar |
| Are hydrogen bonds covalent or non-covalent? | Non-covalent |
| _______________________ form between an atom in one polar covalent bond and an atom in another polar covalent bond when a _______ atom is sandwiched between two electron-attracting atoms. | Hydrogen bonds, hydrogen |
| Hydrogen bonds are easily broken by ___________ | heat/movement |
| Hydrogen bonds occur between __________ charged atoms | partially |
| What kind of interactions are distance dependent and are very weak individually but many together are strong? | Van der Waals |
| What make membranes fluid through an exclusion from water, but are not specific bonds? | Hydrophobic aggregations |
| Because they are polarized, two adjacent H2O molecules can form a linkage known as a __________________ bond | Hydrogen |
| Hydrogen bonds have only about ___________ the strength of a covalent bond | 1/20 |
| Hydrogen bonds are strongest when _____ atoms lie in a ________________ | 3, straight line |
| A hydrogen bond length is approximately __________ as opposed to a covalent bond which is ____________ | .27 nm, .10 nm |
| Many substances such as sugar ______________ in water. This means their molecules separate from each other and become surrounded by water molecules | Dissolve |
| When a substance dissolves in a liquid, the mixture is a ? | solution |
| The dissolved substance in a solution is? | solute |
| The liquid that does the dissolving? | solvent |
| Water is an excellent solvent for many substances because of its ________________ bonds | polar |
| Water can hydrate __________, __________ compounds and dissolve them | soluble, polar |
| Substances that dissolve readily in water are termed hydro____________ | philic |
| ______________________ molecules are composed of ions or polar molecules that attract water molecules through electrical charge effects. Water molecules surround each ion or polar molecule on the surface of a solid substance and carry it into __________ | hydrophilic, solution |
| Water breaks _________ and __________ bonds between other substances | ionic, hydrogen |
| ________ substances dissolve because ____________ molecules are attracted to the positive or negative charge of each ion | Ionic, water |
| ___________ substances such as urea dissolve because their molecules form ______________ bonds with surrounding water molecules | Polar, hydrogen |
| What are the two worlds in a cell? | Polar, aqueous, hydrophilic; non-polar, lipid-like, hydrophobic |
| Which world of the cell has water soluble compounds? | Polar, aqueous, hydrophilic |
| Which world of the cell accounts for cell membranes? | Non polar, lipid-like, hydrophobic |
| Cytoplasm, nucleoplasm, matrix of mitochondria, lumen of ER, golgi, or lysosomes are examples of what world of the cell? | Polar, aqueous, hydrophilic |
| In general, if a compound is much more hydrophobic than hydrophilic, it is a __________ and most likely seen in a ____________ or _________________ | lipid, membrane, fat droplet |
| If a compound is much more hydrophilic than hydrophobic, it is _________________ and most likely seen in an ________________ area | water soluble, aqueous area |
| ______________ means "two natures" where one end is ________________ and the other end is _______________, and one end is _______________ while the other end is _______________ | Amphipathic, polar, nonpolar, hydrophilic, hydrophobic |
| Anionic detergents in water are _______________ where their hydrophilic head ________ the water and their hydrophobic tails ____________________ the water. | Amphipathic, face, face away from |
| Where would you see an asymmetric amphipathic compound if it is more hydrophobic than hydrophilic? | lipid in a membrane |
| Where would you see an asymmetric amphipathic compound if it is more hydrophilic than hydrophobic? | water soluble detergent |
| _____________ is the length of one cycle in the absorption of light | Wavelength |
| _____________ depends on the number of photons in the absorption of light | Intensity |
| Absorption of light by a compound increases/decreases? the intensity of the reflected and transmitted light | decreases |
| What is Beers law? | A = kcI |
| In beers law, the A stands for _______________, k is the ___________________, c is the _________________, and I is _____________ | absorption, constant, concentration, path length |
| A spectrophotometer measures __________________ as the intensity of a selected wavelength of light that is detected traveling through a sample | transmittance |
| __________ means the concentration in moles per liter of hydrogen ions in solution | [H+] |
| When a molecule gains an electron in an aqueous solution, is also ____________ a H+ from solution to balance the charge | picks up |
| In any redox reaction, the molecule that gains Hs has been ________________ | reduced |
| What are the four main types of organic macromolecules? | Carbohydrates, proteins, nucleic acids, lipids |
| What are the building blocks of polysaccharides? | Sugars |
| What are the building blocks of fats/lipids/membranes? | fatty acids |
| What are the building blocks of proteins? | Amino acids |
| What are the building blocks of nucleic acids | Nucleotides |
| In the case of all building blocks of the cell except for fatty acids, the building blocks are converted to the larger units through ______________________ by ____________________ | Covalent polymerization by dehydration |
| How do fatty acids build up to become fats/lipids/membranes? | they cluster via hydrophobic interactions |
| Covalent bonds formed by ______________ reactions hold together the ____________ of macromolecules | condensation, monomers |
| ___________________ interactions are important in interaction of the macromolecule with other molecules and with different parts of itself | Non-covalent |
| Sugars and the molecules made of them are called __________________. The simplest sugars are called ________________ and have the formula __________________. They are usually polar/nonpolar?? | carbohydrates, monosaccharides, C6H1206, polar |
| In condensation, water is _____________ | expelled |
| In hydrolysis, water is _____________ | consumed |
| _____________ and __________ are metabolic sugar polymers that have the storage form of _____________ | Glycogen, starch, glucose |
| __________ is the structural sugar polymer of glucose in cell walls of plants | Cellulose |
| Large linear and branched molecules can be made from simple repeating units where short chains are called ____________________ and long chains are called _________________________. | oligosaccharides, polysaccharides |
| ______________ in animals and _____________ in plants are for energy storage. | Glycogen, starch |
| In plants, a polysaccharide of glucose form cellulose which is important for? | structure and support |
| _________________ can be complex, meaning they are composed of different types of sugar, and are usually linked to _____________ or ____________ | oligosaccharides, proteins, lipids |
| Amino acids come together by __________________ to form ______________ | polymerization, proteins |
| There are __________ different amino acids in cells and the _________________ determines which amino acid it is | 20, side group |
| Proteins are held together by special covalent bonds called ____________________ | peptide bonds |
| Myoglobin is an example of a _____________ | protein |
| _____________ means the 3-D shape of a molecule | Conformation |
| The ____________ of a molecule determines its function. A change in _______________ can inactivate a protein | structure, conformation |
| What are the 4 general groups of amino acids based on? | The side chain (R group) |
| What are the 4 general groups of amino acids? | Polar and full charged, polar uncharged, nonpolar, miscellaneous |
| Polar and full charged amino acids at pH 7 are hydro_________________ | philic |
| Polar but uncharged amino acids at pH 7 are hydro__________ | philic |
| Nonpolar amino acids at pH 7 are hydro__________ | phobic |
| At neutral pH, the amino group is __________ and the carboxyl group is ___________ on a free amino acid | positive, negative |
| Often, charged amino acids may be on the ____________ of soluble proteins where the contribute to the ____________ of the protein in solution. | outside, charge |
| Charged amino acids may interact with each other in the interior of soluble proteins to help a protein ___________________ | fold properly |
| ___________ tend to take H+ out of solution, sometimes by holding protons. At pH 7, these are _________________ charged | Bases, positively |
| ___________ tend to release H+ into solution. At pH 7 these are ______________ charged | Acids negatively |
| A base will lose its ____________ if H+ gets low enough | proton |
| An acid will lose its proton even if the _________ is high | [H+] |
| Water solubility depends on _____________ hydrophobicity | relative |
| What determines which other side chains are ionized and relative hydrophobicity? | The pH of the solution |
| In general, nonpolar (hydrophobic) amino acid side chains can be seen in two places on proteins, where? | Inside protein (hidden away from water), on the outside of membrane proteins (facing membrane lipids) |
| Can a water-soluble protein have many nonpolar amino acids on the outside of it? | Yes, it depends on the relative amount of hydrophobic and hydrophilic groups exposed to the water |
| ________________ bonds stabilizes the folded form of a protein by holding two portions of the protein together, biasing towards folded topology | disulfide |
| The reduction state of a protein cannot/can? affect its conformation? | can |
| The unfolding of a protein is generally oxidation/reduction? and the refolding is generally oxidation/reduction? | Reduction, oxidation |
| What are 5 ways of holding proteins together in proper conformation? | Van der Waals, hydrogen bonds, ionic bonds, hydrophobic aggregations of nonpolar side chains, covalent bonds (peptide, disulfide) |
| Protein-protein interactions can be dependent upon proper _______________ | conformation |
| Formation of an _____________________ requires the right conformation of the enzyme | enzyme-substrate complex |
| Many, but not all proteins are ___________ | enzymes |
| There are ___ different deoxynucleotides in DNA (which are ?) and ________ different nucleotides in RNA (which are ?) | 4, ATGC, 4, AUGC |
| Nucleotides polymerize into nucleic acids by ________________ (loss of water) to form DNA or RNA | condensation |
| What are the three main parts to a nucleotide? | phosphate group, sugar, base |
| The _________ is different in RNA and DNA. If the 2' is an OH, it is a pentose sugar called ___________ and it is the sugar in RNA/DNA?. If the 2' of the sugar is an H, it is called __________ and is the sugar in RNA/DNA? | sugar, ribose, RNA, deoxyribose, DNA |
| Nucleotides are joined together by a _____________________________ between 5' and 3' carbon atoms to form nucleic acids. | Phosphodiester linkage |
| Phosphates of nucleic acids are normally joined to the _________________ of the ribose or deoxyribose sugar. | C5 hydroxyl (5') |
| The phosphate makes a nucleotide ___________ charged | negatively |
| Purines pair with ________________ | pyrimidines |
| ______________ bonding occurs between base pairs of nucleotides. AT and AU have ___ bonds and CG have ___ bonds. | Hydrogen, 2, 3 |
| _________ carry chemical energy in their easily hydrolyzed phsphoanhydride bonds | Nucleotides |
| ___________ are used as signaling molecules in the cell (example: cyclic AMP) | Nucleotides |
| Replication is _______ --> ________. This is DNA _________ | DNA, DNA, synthesis |
| Transcription is _________ --> ________. This is RNA ____________ | DNA, RNA, synthesis |
| Translation is ___________ --> ____________. This is protein _______________ | RNA, protein, synthesis |
| ______________________ can make DNA from RNA | Reverse Transcriptase |
| What are the 3 major types of RNA? | Ribsomal, Transfer, Messenger (rRNA, tRNA, mRNA) |
| 80 to 90% of total RNA is _________ which is never ______________; it is part of the ribosome | rRNA, translated |
| ____________ RNA is never translated, it carries ____________________ to the ribosome | Transfer, amino acids |
| __________ RNA is translated | messenger |
| RNA can be _______________ in RNA viruses and RNAi | double stranded |
| Concentrated solutions of very hydro___________ molecules have little effect on plants cells because the molecules move in so rapidly | phobic |
| Concentrated solutions of substances that don't move in quickly cause ______________ where the cell membrane pulls away from the cell wall as the cell shrinks. | plasmolysis |
| Concentrated solutions of intermediate hydrophobicity cause ________________ followed by _______________ as the hydrophobic solutes moved in. | plasmolysis, deplasmolysis |
| Particles that pass through the lipid bilayer very rapidly have great/little? effect on the shape of cells? | little |
| In plasmolysis/deplasmolysis?, the cell shrinks because water moves out. In plasmolysis/deplasmolysis?, water moves in but the cell can't expand because of the cell wall | plasmolysis, deplasmolysis |
| In an isotonic solution, the concentration of water molecules in solution is ____________ inside the cell and net diffusion will/will not? occur | the same as, will not |
| In a hypertonic solution, the concentration of water molecules in solution is ____________ outside the cell, so water moves _____ and the cell ___________ | lower, out, shrinks |
| In a hypotonic solution, the concentration of water molecules is ____________ outside the cell, so water moves _________ and the cell __________ | greater, out, swells |
| If a cell bursts from hyptotonic swelling, it is called ___________ | lysis |
| Hexane and water don't mix, allowing you to extract? | Lipids from cells |
| Why is tPhospholipids held together in membrane by ____________________ interactions | hydrophobic |
| What does a phospholipid molecule consist of? | Hydrophilic head, two hydrophobic fatty acid tails |
| ______________________ of phospholipids into a bilayer in water makes the membrane ______________ because there are no covalent bonds holding phospholipid to phospholipid | Hydrophobic aggregation, fluid |
| If fatty acids have one or more double bonds in their hydrocarbon tail they are said to be ____________________. | Unsaturated |
| If fatty acids have no double bonds, they are said to be ____________________ | saturated |
| A __________________ in a fatty acid tail can be rigid and create a kink in the chain. The rest of the chain is free to rotate about the other ________________ bonds. | Double bond, C-C |
| _______________________ add kinks and disorder to the packing of fatty acids and side chains, making them more/less? fluid because there is more/less? room to move? | Double bonds, more, more |
| If a fatty acid is more fluid, it has a higher/lower? melting point? | lower |
| Increasing the unsaturation of a fatty acid raises/lowers? the melting point? | lower |
| If a fatty acid is at a temperature above/below? its melting point, it will be more fluid. | above |
| A fatty acid that is not covalently attached to anything. Can be of various lengths. | Free fatty acid |
| A fatty acid that is covalently attached to something (like a triglyceride, phospholipid, or protein) | Fatty acid side chain |
| A fatty acid with no double bonds and is the least fluid. | Saturated fatty acid or saturated side chain |
| Fatty acid with many double bonds, the most fluid. | Polyunsaturated |
| Fatty acid with at least one double bond, a little fluid. | Unsaturated |
| The surface area of the plasma membrane of RBCs are about 50% _____________ and 50% ____________ | phospholipid, protein |
| Biological membranes are _________________ with many proteins moving around freely in the membrane | fluid mosaics |
| Spanning membrane proteins can acts as _____________ through the lipid membrane to let hydro___________ things across. Protein ________ can also help move big things. | channels, philic, transporters |
| Passive transport of glucose is facilitated by a ______________________________. The energy comes from the ____________ gradient | membrane protein carrier, glucose |
| _________________ are membrane proteins that can either let solutes that can't cross the lipid bilayer flow down their concentration gradient through them (passive transport). Examples? | Transporters, ion channels and facilitated diffusion |
| Transporters are membrane proteins that can let solutes that can't cross the lipid bilayer move against their concentration gradient using energy from where? | ATP, sun, coupling the uphill flow of one substance to the downhill flow of another |
| Membranes use __________________ to change energy from one form into another. | Energy transduction |
| Membranes use _____________________ where membrane receptors transmit information across membranes. | Signal transduction |
| Membranes are important for the ________________ of solutes. | Transport |
| Membranes are important for ______________________ (keeping all the parts of the cell together), _________________ for biochemical activities, and has a _____________________ to keep good things in and filter bad things out. | Compartmentalization, scaffold, selective permeability barrier |
| __________________ are small, amphipathic, lipid-like molecules that have both a hydrophilic and a hydrophobic region. They have a single _______________________ which makes them more cone-shaped than lipids. | Detergents, hydrophobic tail |
| Detergents tend to aggregate into small clusters called _________________ rather than forming a bilayer. | Micelles |
| When mixed with membranes, the hydro_____________ parts of detergents bind to the hydro____________ parts of phospholipids and proteins. This association tends to __________ the lipids and the proteins | Phobic, phobic, solubilize |
| ________ is ionic while _________ is non-ionic. Ionic detergents not only displace proteins from lipid bilayers, but unfold the proteins as well due to ___________ of charges. | SDS, Triton, repulsion |
| __________________ are proteins with covalently attached sugars. The sugars face the inside/outside? of the cell when they are on the plasma membrane. Not all membrane proteins are this but most _______________ are if they face the outside of the cell. | Glycoproteins, outside, receptors |
| _______________ are lipids with covalently attached sugars. The sugars face the inside/outside? of the cell when they are on the plasma membrane. | Glycolipids, outside. |
| _____________ are defined as the water-insoluble molecules in cells that are soluble in organic solvents. Two common types are _______________ and __________________ which are both made from isoprene units. | Lipids, steroids, polyisoprenoids. |
| Cholesterol is a ______________________ but testosterone is not. | membrane sterol |
| Steroids have a common _________________ structure. | Multiple-ring |
| Cholesterol, testosterone, and estrogen are examples of _________________, which are not found in prokaryotes. | Sterols |
| Which type of lipid is usually in membranes, usually amphipathic, and include phospholipids and sterols? | Structural lipids |
| What type of lipids are not found in membranes, are hydrophobic, and usually in fat droplets? | Metabolic lipids (triglycerides) |
| What kind of membrane protein is not soluble in water and stays on the membrane in high salt? | Integral |
| What kind of membrane protein is attached to the membrane by ionic bonds and can be solubilized (removed) from the membrane with high salt.They can be one either side of the membrane and attached by ionic bonds to what? | Peripheral, proteins, lipids, or sugars |
| What kind of membrane protein is covalently attached to a membrane lipid and is not peripheral? | Lipid-anchored |
| You can tell if a protein membrane is peripheral or integral using what process? If the protein is in the pellet, it is ________. If the protein is in the supernatant, it was ______________. | centrofugation with high salt, integral, peripheral. |
| Membranes can be _______________, meaning they do not always have the same phospholipids in both halves of the membrane bilayer | Asymmetrical |
| What is the use of cholesterol in membrane permeability? | It prevents 'leakiness' of fluid membranes |
| Membrane fluidity is important for providing a ______________ environment for integral membrane proteins | Solvent |
| Membrane fluidity is important for membrane movement during what processes? | Growth, motility, endocytosis, fusion, etc |
| Why does the percentage of mosaics increase at higher temperatures? | As temp rises, fluidity increases and membranes mix more. |
| In a protein, the ___________ and ____________ are tied up in the peptide bond so are not charged. | Alpha amino and carboxyl |
| ______________ are polymers of amino acids. | Proteins |
| Free amino acids all have a ________________ group and ________________ group | amino, carboxyl |
| Amino acids are covalently attached by ____________ bonds between neighboring ________ and __________ groups. | Peptide, amino, carboxyl |
| The charge on the protein is dependent on the _______ | pH |